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Home › Medications › amitriptyline

amitriptyline

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of amitriptyline

7 trials tracked of amitriptyline: 3 in phase 3 or 4 and 1 with published results. The most-cited published study has 187 citations.

7Trials tracked
3Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 3 Phase 2 3 Other / NA 1
  1. Phase 3 Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS) Completed · 187 cited
  2. Phase 3 Novel Topical Therapies for the Treatment of Genital Pain Completed
  3. Phase 3 Functional Dyspepsia Treatment Trial Completed
  4. Phase 2 Amitriptyline to Prevent Headache After Traumatic Brain Injury Completed
  5. Phase 2 Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD) Completed
  6. Phase 2 Trial of Amitriptyline for Chronic Oral Food Refusal in Children 9 Months to 8 Years of Age Completed
Show 1 more trials
  1. N/A Physiology of GERD and Treatment Response Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Desipramine shows large effect in adolescent MDD while other antidepressants show no significant difference
Psychiatry Meta-analysis
Desipramine shows large effect in adolescent MDD while other antidepressants show no significant difference Analysis shows only one antidepressant outperformed placebo for teen depression
This systematic review and network meta-analysis evaluated five antidepressants for adolescent MDD. While desipramine showed a large effect …
New data reveals that while most common antidepressants showed no significant difference from a placebo for teens with depression.
Frontiers Aug 28, 2026
Proof of concept study uses preSCRIPT framework to annotate prescriptions in UK Biobank
Genetics & Precision Medicine
Proof of concept study uses preSCRIPT framework to annotate prescriptions in UK Biobank preSCRIPT framework identifies genetic links to drug response in UK Biobank
This proof of concept study utilized the preSCRIPT framework to filter and annotate raw prescription data from the UK Biobank, which include…
A proof of concept study in the UK Biobank used preSCRIPT to find genetic links to how people respond to common medications like warfarin an…
medRxiv Apr 30, 2026
Systematic review finds limited evidence for antibiotics in low back pain with Modic changes
Geriatrics & Aging Sys. Review
Systematic review finds limited evidence for antibiotics in low back pain with Modic changes Antibiotics Might Ease Back Pain for Some
A systematic review of 3 RCTs (402 adults) found amoxicillin may slightly reduce pain and disability at 12-14 weeks in patients with low bac…
For people with low back pain and specific MRI changes, antibiotics could treat the root cause instead of just masking the pain.
Cochrane Apr 11, 2026