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Home › Medications › amoxicillin

amoxicillin

15 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of amoxicillin

23 trials tracked of amoxicillin: 12 in phase 3 or 4 and 9 with published results. The most-cited published study has 464 citations.

23Trials tracked
12Phase 3 & 4
0Recruiting
9With published results
Phase distribution
Phase 4 7 Phase 3 5 Phase 2 4 Phase 1 3 Other / NA 4
  1. Phase 4 Alternative Antibiotic Regime in the Treatment of GAgP Completed · 464 cited
  2. Phase 3 Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection Completed · 305 cited
  3. Phase 4 Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children Completed · 156 cited
  4. Phase 3 Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis Completed · 93 cited
  5. Phase 4 Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso Completed · 61 cited
  6. Phase 4 Oral Challenge in the Pediatric ED Completed · 37 cited
Show 17 more trials
  1. Phase 4 Penicillin De-labeling in the Pediatric Primary Care Setting Completed · 28 cited
  2. Phase 3 Azithromycin for Uncomplicated Severe Acute Malnutrition in Burkina Faso (Pilot) Completed · 9 cited
  3. Phase 3 A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection Completed · 6 cited
  4. Phase 4 High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population Completed
  5. Phase 4 Treatment of Acute Sinusitis Completed
  6. Phase 3 Amoxicillin Versus Benzyl Penicillin for Treatment of Children Hospitalised With Severe Pneumonia Completed
  7. Phase 2 Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers Completed
  8. Phase 2 A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules Completed
  9. Phase 2 Efficacy and Safety After Multiple Doses of TNP-2198 Capsules, Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules in Helicobacter Pylori Infected-positive Participants Completed
  10. Phase 2 Treatment of Gardnerella Vaginalis Vaginal Colonization With Amoxicillin Completed
  11. Phase 1 A Study of Vonoprazan in Adults With Helicobacter Pylori Completed
  12. Phase 1 TAK-438 Bismuth Drug Interaction Study Completed
  13. Phase 1 Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia Completed
  14. N/A Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota Completed
  15. N/A Compare Sequential and Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea Completed
  16. N/A Antibiotic Efficacy in Pneumonitis Following Paraffin (Kerosene) Ingestion in Children Completed
  17. N/A Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients Completed

Showing the 23 most-cited and recently-updated of 23 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review finds limited evidence for antibiotics in low back pain with Modic changes
Geriatrics & Aging Sys. Review
Systematic review finds limited evidence for antibiotics in low back pain with Modic changes Antibiotics Might Ease Back Pain for Some
A systematic review of 3 RCTs (402 adults) found amoxicillin may slightly reduce pain and disability at 12-14 weeks in patients with low bac…
For people with low back pain and specific MRI changes, antibiotics could treat the root cause instead of just masking the pain.
Cochrane Apr 11, 2026
Vonoprazan-based regimens show higher H. pylori eradication rates than rabeprazole dual therapy in Chinese cohort
Anesthesiology & Pain Medicine Cohort
Vonoprazan-based regimens show higher H. pylori eradication rates than rabeprazole dual therapy in Chinese cohort A New Stomach Infection Treatment Works Where Old Ones Often Fail
A retrospective cohort study of 598 H. pylori-positive outpatients in Guizhou, China, found vonoprazan-based regimens achieved eradication r…
For millions struggling with a common and stubborn stomach bug, a new treatment approach just proved it can succeed where standard care freq…
Frontiers Apr 11, 2026
Adjunctive antibiotics in peri-implantitis surgery reduce bleeding on probing but not other outcomes
Infectious Disease RCT
Adjunctive antibiotics in peri-implantitis surgery reduce bleeding on probing but not other outcomes Antibiotics with surgery reduced gum bleeding around dental implants in small study
A 12-month RCT in 59 patients with peri-implantitis found that adding systemic amoxicillin and metronidazole to access-flap surgery signific…
Adding antibiotics to dental implant surgery reduced gum bleeding around implants, but offered no other benefits after one year.
Apr 3, 2026