Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
New trial to test azithromycin vs doxycycline for pneumonia
This is a protocol for a planned randomized clinical trial involving 1120 adult patients hospitalized with community-acquired pneumonia. No …
A large trial will compare two antibiotic combos for hospitalized pneumonia patients. Which works better?
Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia
Shorter antibiotics work just as well for pneumonia
This meta-analysis of 21 RCTs found that short-course antibiotic therapy (≤5 days) provides comparable clinical, bacteriological, and radiol…
For adults with pneumonia, 5 days or less of antibiotics works as well as longer courses, with fewer severe side effects.
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia
Shorter hospital stays and fever for kids with pneumonia using steroids
This systematic review and meta-analysis evaluated systemic corticosteroid therapy versus controls in children with community-acquired pneum…
A large review found that adding steroids to standard antibiotics helped children with pneumonia leave the hospital faster and get over thei…
High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions
Community-acquired pneumonia kills one in three ICU patients in low- and middle-income countries
A systematic review and meta-analysis of 48,707 patients reveals stark mortality risks for community-acquired pneumonia in resource-limited …
A massive review shows that one in three patients with pneumonia admitted to ICUs in low- and middle-income countries dies within a month.
FDA approves nuzyra for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections in adults
FDA approves nuzyra for treating bacterial infections in adult patients safely
The FDA granted approval for nuzyra to treat community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections i…
The FDA has approved nuzyra to treat community-acquired bacterial pneumonia and skin infections in adults. This regulatory decision confirms…
Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia
Doctors find amoxicillin works just as well as other drugs for pneumonia
A systematic review and meta-analysis compared amoxicillin and amoxicillin-clavulanate to other antibiotics for community-acquired pneumonia…
New research shows a common antibiotic called amoxicillin works just as well as other options for treating pneumonia in people of all ages.
Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection
Premature birth and wheezing raise severe HMPV pneumonia risk
This retrospective cohort study examined 878 hospitalized children with human metapneumovirus (HMPV)-positive community-acquired pneumonia (…
A study of 878 children finds premature birth and wheezing are strong predictors of severe HMPV pneumonia.
Nemonoxacin shows similar efficacy to moxifloxacin in hospitalized CAP patients
New pneumonia drug saves money while matching standard care results
This retrospective cohort study of 196 hospitalized patients with community-acquired pneumonia found that nemonoxacin injection had 100.0% c…
A new pneumonia drug saves hospital costs while working just as well as the standard treatment for patients.
Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort
Resistant pneumonia keeps kids sicker for days
This retrospective cohort of 71 pediatric patients in China found a 94.4% prevalence of macrolide-resistant M.
In one Chinese hospital, 94% of child pneumonia cases resisted common antibiotics, leading to longer fevers and hospital stays.
Machine learning models outperformed APACHE-II for predicting mortality in severe community-acquired pneumonia patients with respiratory failure
Machine learning models may predict pneumonia death risk better than standard scores in ICU patients
This retrospective cohort study evaluated machine learning models versus the Acute Physiology and Chronic Health Evaluation II (APACHE-II) s…
New computer models predict pneumonia death risk in ICU patients more accurately than standard scores doctors currently use.
tNGS in pediatric LRTIs shows higher Mycoplasma pneumoniae detection in severe vs non-severe CAP
A new test found more germs in severe pediatric pneumonia cases than mild ones
A retrospective, single-center cohort study of 2,299 children with suspected lower respiratory tract infections found that targeted next-gen…
A new test found that severe pediatric pneumonia cases carry more germs than mild ones, revealing a link between specific microbial signatur…
Systemic Immune-Inflammation Index predicts severe community-acquired pneumonia in pediatric patients
High Blood Markers Signal Dangerous Pneumia in Kids
This retrospective analysis evaluated 595 pediatric patients to assess the Systemic Immune-Inflammation Index (SII) for predicting severe pn…
A simple blood test number called SII helps doctors spot dangerous pneumonia in children before their lungs fill with fluid.
Research across Pneumonia
Related studies from across the Pneumonia family.
AI models provide high accuracy for pulmonary inflammation and COVID-19 detection in diverse populations
Artificial Intelligence Shows Promise for Detecting Lung Inflammation
This mini-review synthesizes evidence on artificial intelligence applications for detecting pulmonary inflammation and managing perioperativ…
New research shows that artificial intelligence tools can accurately identify lung conditions like pneumonia and COVID-19 from medical imagi…
Airway clearance techniques triple odds of treatment success in Chinese pneumonia patients
Airway clearance techniques may improve treatment for pneumonia patients
This meta-analysis of RCTs in Chinese adults with pneumonia found that adding airway clearance techniques to conventional treatment signific…
Adding airway clearance to standard care may help Chinese adults with pneumonia breathe better and face fewer complications.
AI diagnostic tools show high accuracy but limited real-world validation in systematic review
Artificial intelligence shows high accuracy in detecting various medical conditions
This systematic review of 24 studies synthesizes evidence on AI and deep learning for disease detection across multiple imaging modalities. …
New analysis of 24 studies shows AI tools can reach over 90% accuracy in spotting everything from lung cancer to skin disorders.
CD4+ T cells and Tim-3 regulate immune responses and cytokine-mediated injury in severe pediatric pneumonia
Immune system hurdles shape severity of severe childhood pneumonia
This narrative review examines how CD4+ T cells, Tim-3 (HAVCR2), and cytokines influence the host immune response in severe pneumonia. The a…
New research explores how specific immune cells and proteins may drive the intense inflammation seen in children with severe pneumonia.
Brain-Lung-Immune-Microbiome Axis replaces biomechanical models in understanding ventilator-associated pneumonia after traumatic brain injury
New Framework Explains Lung Infections After Brain Injuries
This narrative review explores the transition from a traditional biomechanical model of ventilator-associated pneumonia to a multidimensiona…
A new model suggests that brain injuries create a complex immune and microbiome response that leads to lung infections in intensive care pat…
Adrenergic receptor signaling modulates pulmonary innate immunity and barrier integrity in acute lung injury
Understanding How Nerve Signals Influence Lung Health During Severe Respiratory Infections
This systematic review synthesizes the role of adrenergic receptors (ARs) as a molecular interface between the sympathetic nervous system an…
New research explores how specific nerve signals help control inflammation and protect the lungs during severe lung infections.
Colistin-based inhalation regimens rank highest for clinical response in multidrug-resistant Acinetobacter baumannii pneumonia
Colistin Inhalation Tops for Drug-Resistant Pneumonia
This network meta-analysis of 1420 patients with multidrug-resistant Acinetobacter baumannii (MDRAB) pneumonia compared colistin, tigecyclin…
For tough pneumonia, inhaled colistin works best, but sulbactam is a good alternative without the toxicity.
Nebulised Chinese herbal medicine as adjunctive therapy improves clinical effective rate in pediatric pneumonia
Chinese Herbal Medicine Boosts Pneumonia Treatment in Children
This meta-analysis of randomized controlled trials evaluated nebulised Chinese herbal medicine as an adjunctive therapy for pediatric pneumo…
Adding nebulised Chinese herbal medicine to standard care improved pneumonia recovery in children, a meta-analysis of 1,764 patients found.
No risk score outperformed WHO IMCI criteria for predicting pediatric pneumonia mortality
Risk Scores Do Not Outperform Standard Care for Pneumonia
This secondary analysis of a randomized controlled trial evaluated five risk scores in 1010 children with pneumonia across five African coun…
New analysis shows standard clinical tools are just as effective as complex risk scores for predicting pneumonia outcomes in children.
Evaluating the Impact of Rapid Diagnostic Panels on Pediatric Pneumonia Management
New Testing Panel May Help Target Antibiotics for Child Pneumonia
A randomized trial explores how rapid diagnostic panels influence antibiotic adjustments and de-escalation for children with pneumonia.
A new testing panel may help doctors more accurately target antibiotics and reduce unnecessary medications for children with pneumonia.
Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia
Inhaled antibiotics help cure pneumonia and lower death risk in ICU patients
This systematic review and meta-analysis of adjunctive inhaled antibiotics for ventilator-associated pneumonia found significantly improved …
Adding inhaled antibiotics to standard care improved cure rates and reduced death in patients with ventilator-associated pneumonia.
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
Non-invasive ventilation may help patients with Madelung's disease and respiratory failure
This case series describes non-invasive ventilation using a total face mask in two patients with Madelung's disease who experienced acute re…
A small case series suggests non-invasive ventilation can manage acute respiratory failure in patients with Madelung's disease, though more …
Questions about Community-Acquired Pneumonia
What are the risks of co-infection in children with HMPV and severe community-acquired pneumonia?
Co-infection, especially with Mycoplasma pneumoniae, is a significant risk factor for severe CAP in children with HMPV, with studies showing higher rates of co-infection in severe cases.
Full answer →Are children with severe community-acquired pneumonia more likely to have Mycoplasma pneumoniae?
Yes, children with severe community-acquired pneumonia are more likely to have Mycoplasma pneumoniae, with studies showing higher detection rates in severe cases.
Full answer →Can machine learning predict mortality better than APACHE-II for severe community-acquired pneumonia?
Yes, machine learning models, particularly GBDT and XGBoost, have outperformed APACHE-II in predicting mortality for severe community-acquired pneumonia with respiratory failure.
Full answer →What is the severe community-acquired pneumonia rate for children with HMPV?
In a recent study of hospitalized children with HMPV, 28.0% had severe community-acquired pneumonia (CAP).
Full answer →How does the severity of community-acquired pneumonia affect the detection of Mycoplasma pneumoniae in children?
Severe community-acquired pneumonia in children is associated with higher detection rates of Mycoplasma pneumoniae compared to non-severe cases, likely due to higher bacterial load and immune response.
Full answer →Does amoxicillin work just as well as other antibiotics for community-acquired pneumonia?
Current evidence suggests amoxicillin is generally as effective as other antibiotics for community-acquired pneumonia, but the choice depends on local resistance patterns and patient factors.
Full answer →All Community-Acquired Pneumonia Articles
- Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
- Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia
- Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia
- High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions
- FDA approves nuzyra for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections in adults
- Meta-analysis finds no clear difference between amoxicillin and other antibiotics for community-acquired pneumonia
- Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection
- Nemonoxacin shows similar efficacy to moxifloxacin in hospitalized CAP patients
- Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort
- Machine learning models outperformed APACHE-II for predicting mortality in severe community-acquired pneumonia patients with respiratory failure
- tNGS in pediatric LRTIs shows higher Mycoplasma pneumoniae detection in severe vs non-severe CAP
- Systemic Immune-Inflammation Index predicts severe community-acquired pneumonia in pediatric patients
- Pyroptosis endotypes and malnutrition linked to mortality in older adults with community-acquired pneumonia
- Immune dysregulation score predicts mortality and identifies hydrocortisone responders in community-acquired pneumonia
- U.S. pediatric hospitals report increase in Mycoplasma pneumoniae pneumonia discharges in children
- Contezolid shows 80% clinical cure rate in small pneumonia study with good pulmonary penetration