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Neurology
Meta-analysis
GABA-modulating pharmacotherapies show inconsistent results for improving symptoms in autism spectrum disorder
New data shows mixed results for medications targeting autism symptoms
This meta-analysis evaluated the impact of bumetanide, arbaclofen, and valproate on various symptom domains in individuals with autism spect…
Research into three specific drugs for autism shows some initial signs of improvement, but the evidence is currently too inconsistent to be …
medRxiv
Aug 25, 2026
Psychiatry
RCT
Bumetanide shows individual-level improvement in heterogeneous neurodevelopmental cohort
Bumetanide helps mood and sleep in kids with sensory issues
In a post-trial access study using a multiple-baseline single-case experimental design, 113 youth (7–19 years) with ASD, ADHD, epilepsy, or …
Kids with autism, ADHD, or epilepsy who feel sensory overload saw better mood and sleep after taking bumetanide.
medRxiv
Apr 24, 2026