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Home › Medications › clarithromycin

clarithromycin

6 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of clarithromycin

30 trials tracked of clarithromycin: 9 in phase 3 or 4 and 3 with published results. The most-cited published study has 284 citations.

30Trials tracked
9Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 1 Phase 3 8 Phase 2 3 Phase 1 13 Other / NA 5
  1. Phase 3 Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection Completed · 284 cited
  2. Phase 3 Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis Completed · 93 cited
  3. Phase 3 A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection Completed · 5 cited
  4. Phase 4 High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population Completed
  5. Phase 3 A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD) Completed
  6. Phase 3 Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia Completed
Show 24 more trials
  1. Phase 3 Asthma Clinical Research Network (ACRN) Trial - Macrolides in Asthma (MIA) Completed
  2. Phase 3 Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia (CAP) Completed
  3. Phase 3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed
  4. Phase 2 Lenalidomide, Dexamethasone, and Clarithromycin in Treating Patients Who Have Undergone Stem Cell Transplant for Multiple Myeloma Completed
  5. Phase 2 Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma Completed
  6. Phase 2 Phase II Study of Thalidomide, Clarithromycin, Lenalidomide, and Dexamethasone for Newly Diagnosed Multiple Myeloma Completed
  7. Phase 1 A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants Completed
  8. Phase 1 CYP3A4 Activity and Mineral Homeostasis Completed
  9. Phase 1 Drug-Drug Interaction Study of Colchicine and Clarithromycin Completed
  10. Phase 1 Clarithromycin 500 mg Tablets Under Non-Fasting Conditions Completed
  11. Phase 1 Clarithromycin 500 mg Tablets Under Fasting Conditions Completed
  12. Phase 1 A Study to Evaluate the Effect of Clarithromycin on LY2216684 Completed
  13. Phase 1 A Study of Vonoprazan in Adults With Helicobacter Pylori Completed
  14. Phase 1 The Effect of Gemfibrozil, Ketoconazole and Clarithromycin on the Amount of LY2409021 in the Bloodstream Completed
  15. Phase 1 Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma Completed
  16. Phase 1 TAK-438 Bismuth Drug Interaction Study Completed
  17. Phase 1 A Study of LY2835219 in Participants With Cancer Completed
  18. Phase 1 The Potential of Givinostat as DDI Victim in Co-administration P-gp Inhibitor (Part 2) Completed
  19. Phase 1 Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies Completed
  20. N/A Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery Completed
  21. N/A Compare Sequential and Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea Completed
  22. N/A Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication" Completed
  23. N/A Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients Completed
  24. N/A Clarithromycin as Adjuvant to Periodontal Debridement Completed

Showing the 30 most-cited and recently-updated of 30 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Susceptibility-guided sequential therapy shows no superiority over empirical therapy for H. pylori eradication
Infectious Disease RCT
Susceptibility-guided sequential therapy shows no superiority over empirical therapy for H. pylori eradication Susceptibility-guided therapy did not beat standard treatment for stomach bug infections
This randomised controlled trial in 500 treatment-naive adults with H. pylori infection compared susceptibility-guided sequential therapy to…
A new trial found that testing for drug resistance before treatment did not improve cure rates compared to standard care for stomach infecti…
Jun 1, 2026
Bismuth quadruple therapy shows higher H. pylori eradication in pediatric patients with clarithromycin resistance
Gastroenterology RCT
Bismuth quadruple therapy shows higher H. pylori eradication in pediatric patients with clarithromycin resistance High-Level Clarithromycin Resistance May Predict Bismuth Success in H. pylori
This observational study of 4,610 pediatric patients with H. pylori infection compared bismuth quadruple therapy to triple therapy. Bismuth …
A simple blood test level may predict which H. pylori infections respond best to bismuth therapy, turning a treatment failure sign into a gu…
medRxiv May 2, 2026
Meta-analysis: Nitazoxanide triple therapy improves H. pylori eradication vs standard triple therapy
Infectious Disease Meta-analysis
Meta-analysis: Nitazoxanide triple therapy improves H. pylori eradication vs standard triple therapy Nitazoxanide triple therapy significantly improves H. pylori cure rates compared to standard treatment
This systematic review and meta-analysis of 1286 participants found that nitazoxanide-based triple therapy significantly improved H.
A large review of 1286 patients found that adding nitazoxanide to standard triple therapy significantly improved H. pylori cure rates and re…
May 1, 2026
Retrospective study compares antibiotic regimens for H. pylori eradication in children
Pediatrics Cohort
Retrospective study compares antibiotic regimens for H. pylori eradication in children Two antibiotic regimens cleared H. pylori in most children within four weeks
This retrospective observational study evaluated two antibiotic combinations for treating Helicobacter pylori infection in children aged 4 t…
A look at two common treatments found that both regimens successfully eliminated the bacteria in most children within four weeks.
Frontiers Apr 23, 2026
Bismuth-containing quadruple therapy associated with higher H. pylori eradication rates compared to triple therapy in children
Pediatrics Cohort
Bismuth-containing quadruple therapy associated with higher H. pylori eradication rates compared to triple therapy in children New Mix Clears Stomach Bugs Better in Children
This retrospective cohort study of 161 pediatric patients compared 14-day bismuth-containing quadruple therapy against triple therapy for He…
A four-drug plan works better than the usual three-drug plan for clearing stomach bacteria in kids.
Frontiers Apr 22, 2026
H. pylori eradication reduces cholesterol and LDL in patients with cardiovascular disease risk
Infectious Disease RCT
H. pylori eradication reduces cholesterol and LDL in patients with cardiovascular disease risk Treating This Stomach Bug May Quietly Lower Heart Risk
A randomized controlled trial in 72 patients with H.
Treating a common stomach infection can lower cholesterol and small dense lipoprotein particles a year later, potentially reducing heart dis…
Apr 15, 2026