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Patient Mode — summaries use plain language, avoiding clinical jargon.
Diabetes & Endocrinology
Cohort
Higher third trimester estradiol levels associated with maternal hypothyroxinemia and lower FT4
High Estradiol Levels Link to Low Thyroid Hormone in Late Pregnancy
This cohort study of 200 women at 28 weeks gestation or later found that higher estradiol levels were associated with maternal hypothyroxine…
High pregnancy hormones may explain why thyroid hormone drops in late pregnancy without raising TSH levels.
Frontiers
Apr 30, 2026
Oncology
RCT
Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival
Men with advanced prostate cancer may have fewer hot flashes with a new patch treatment.
This phase 3 randomized trial evaluated 1360 men with locally advanced prostate cancer across 75 U.K. centers. Transdermal estradiol patches…
A new patch for advanced prostate cancer showed similar cancer control to standard shots but caused fewer hot flashes in a large UK trial.
Apr 23, 2026
Diabetes & Endocrinology
Sys. Review
Systematic review finds no progestogen class effect in oral contraception, with varying safety profiles
A Safer Pill? How a New Generation of Birth Control May Lower Your Risk
A systematic review of oral contraception in women found no class effect among progestogens. Progestogen-only pills showed high efficacy and…
New birth control pills using natural estrogens may lower blood clot risks compared to older versions, offering a safer option for millions …
Frontiers
Apr 12, 2026
Neurology
Phase II
Phase 2 trial compares lidocaine/estradiol cream, nortriptyline, and combination for vestibulodynia subtypes
Can a cream or pill help women with chronic pelvic pain?
A 52-month, phase 2, randomized, double-blinded, placebo-controlled trial in 209 women with distinct vestibulodynia subtypes compared 5% lid…
Women with chronic pelvic pain may finally find relief as a new trial compares creams, pills, and combined treatments to personalize care fo…
CT.gov
Apr 3, 2026