Intravesical aminoglycoside instillations reduce recurrent urinary tract infection risk with an IRR of 0.23
New findings show ways to reduce recurring urinary tract infections
This systematic review and meta-analysis of 25 studies evaluates intravesical instillations for preventing recurrent urinary tract infection…
Doctors are looking at new ways to stop repeat urinary tract infections using local treatments like aminoglycosides or hyaluronic acid.
Gram-negative organisms and multidrug resistance are prevalent in dental unit waterlines
Bacteria in dental water lines show resistance to common antibiotics
This scoping review of 18 studies identifies a prevalence of Gram-negative organisms, such as Pseudomonas spp., in dental unit waterlines. T…
Research shows that bacteria found in dental unit waterlines can resist several common types of antibiotics used to treat infections.
Ampicillin-gentamicin cuts chorioamnionitis risk to 1.9% vs 10.6% with ampicillin alone in PROM
Adding gentamicin to ampicillin cuts infection rates for women with long-term water breaks
This randomized controlled trial in 207 women with term PROM compared intravenous ampicillin-gentamicin to ampicillin alone. The combination…
A trial found that adding gentamicin to ampicillin lowered infection risks for women with prolonged water breaks, offering a clearer path to…
Case report of high-dose ceftazidime in an 84-year-old man with skull base osteomyelitis and type 1 diabetes
High-dose antibiotic shows partial skull base infection resolution
This case report describes an 84-year-old man with type 1 diabetes, vascular comorbidity, and advanced frailty treated for skull base osteom…
An 84-year-old man with diabetes and a rare skull infection saw some improvement with a long antibiotic course, but his condition remained c…
Systematic review and meta-analysis of pneumonia prevalence and antimicrobial resistance in Ghana
Ghana's pneumonia rate hits 22 percent with one region most at risk
This systematic review and meta-analysis synthesizes data on pneumonia prevalence and antimicrobial resistance patterns among participants i…
A new review finds 22 percent of Ghanaians have pneumonia, with children under 5 especially vulnerable and widespread resistance to common a…
Narrative review suggests phytochemicals and phages may augment conventional antibiotics for brucellosis
New plant-based and phage options might help treat stubborn brucellosis infections in people and animals
This narrative review discusses novel strategies for treating brucellosis in humans and animals. The authors note that conventional antibiot…
Standard antibiotics sometimes fail to cure brucellosis, and bacteria are becoming resistant. New methods using plant chemicals and viruses …
Weekend births linked to longer antibiotic exposure in very low birth weight infants with suspected sepsis
Weekend births delay antibiotic stops for fragile newborns
This retrospective cohort study examined antibiotic exposure times in very low birth weight infants with suspected early-onset sepsis and ne…
New research shows babies born on weekends stay on antibiotics longer than those born during the work week.
Genomic analysis shows clonal Campylobacter persistence and gentamicin resistance in two CVID patients
Why Your Chicken Could Be Making You Sick
This observational case series analyzed recurrent Campylobacter bacteremia in two patients with common variable immunodeficiency over 6 to 1…
New DNA testing shows people with weak immune systems get sick from the exact same chicken bacteria strain over many years, likely because t…
Guidelines outline antimicrobial treatment and prophylaxis recommendations for human plague
Health experts issue updated treatment guidelines for plague infections
A guideline document provides recommended best practices for antimicrobial treatment and prophylaxis of human plague in naturally acquired i…
Updated guidelines now tell doctors how to treat and prevent plague infections from natural outbreaks or bioterrorism attacks.