Meta-analysis finds no stroke benefit but possible bleeding risk with continued OAC after AF ablation
Stopping blood thinners after heart rhythm repair does not lower stroke risk
This meta-analysis evaluated six studies involving patients who met conventional guideline thresholds for oral anticoagulation after apparen…
A large review found that stopping blood thinners after heart rhythm repair did not lower stroke risk and might slightly raise bleeding risk…
Proof of concept study uses preSCRIPT framework to annotate prescriptions in UK Biobank
preSCRIPT framework identifies genetic links to drug response in UK Biobank
This proof of concept study utilized the preSCRIPT framework to filter and annotate raw prescription data from the UK Biobank, which include…
A proof of concept study in the UK Biobank used preSCRIPT to find genetic links to how people respond to common medications like warfarin an…
Network meta-analysis of LMWH and aspirin for high-risk singleton pregnancies with fetal growth restriction
New Treatment Cuts Risk of Dangerous Pregnancy Complication
This network meta-analysis evaluated low-molecular-weight heparin (LMWH) and low-dose aspirin (LDA) in singleton pregnancies at high risk of…
Low-dose blood thinners combined with aspirin significantly reduce the risk of dangerous fetal growth restriction in high-risk pregnancies.
Prospective observational study identifies 2,504 potential drug-drug interactions among hospitalized patients with acute coronary syndrome.
Heart Patients Face Hidden Risks From Common Drug Mixes
This prospective observational cohort study evaluated 371 hospitalized patients with acute coronary syndrome at Assiut University Heart Hosp…
Taking several heart medications at once can create dangerous hidden interactions that increase the risk of treatment failure and hospital s…
Narrative review examines left atrial appendage closure for stroke prevention in atrial fibrillation.
The Tiny Ear-Shaped Pouch in Your Heart That Could Cause a Stroke
This narrative review evaluates left atrial appendage (LAA) closure as an alternative to warfarin, aspirin, or DOAC therapy for adults with …
A small heart implant seals off a stroke-risk pouch for atrial fibrillation patients who can't safely take blood thinners, with success rate…
VerifyNow-guided antiplatelet modification linked to lower stroke recurrence in atherothrombotic or lacunar infarction
Testing Blood Saves Stroke Patients From Recurrence
A retrospective observational study of 243 patients with atherothrombotic or lacunar infarction found that VerifyNow-guided antiplatelet the…
Doctors who adjusted blood thinner choices based on a simple blood test saw far fewer repeat strokes in patients with prior clots.
Cerebral infarction common in tuberculous meningitis and linked to disease severity and arterial occlusion
Could blood thinners or specific treatments make brain strokes worse in severe meningitis?
This secondary analysis of the ACT-TBM randomized trial examined 226 patients with tuberculous meningitis at two tertiary centers in India. …
Patients with tuberculous meningitis and blocked arteries were much more likely to develop strokes, especially if they received modified tub…
Aspirin and NSAIDs show little benefit for colorectal cancer prevention within 15 years but increase bleeding risk.
The Aspirin-Cancer Question Has a Complicated Answer
This Cochrane meta-analysis of randomized controlled trials involving 124,837 participants evaluated aspirin and nonsteroidal anti-inflammat…
A major new review finds that taking daily aspirin to prevent colon cancer offers little benefit for the first 15 years while increasing ble…
Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance.
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
Web of White Blood Cells Linked to Pregnancy Risks
A systematic review of emerging evidence indicates that dysregulation of neutrophil extracellular trap (NET) formation and clearance is stro…
A sticky web of white blood cells meant to fight germs can instead trigger serious pregnancy risks like preeclampsia and preterm birth when …
Ticagrelor Not Noninferior to Prasugrel in Diabetes Patients With Multivessel CAD After PCI
New study shows ticagrelor did not beat prasugrel for heart attack prevention in diabetics
This randomized clinical trial of 1,800 patients with diabetes and multivessel coronary artery disease undergoing PCI compared ticagrelor pl…
For diabetics with heart stents, a new study found ticagrelor offered no clear advantage over prasugrel in preventing death, heart attacks, …
Adding low-dose rivaroxaban to DAPT did not significantly reduce LV thrombus in anterior STEMI patients.
Adding low-dose rivaroxaban to standard heart attack drugs did not clearly prevent blood clots in the heart
This randomized clinical trial evaluated 560 patients with anterior ST-segment elevation myocardial infarction (STEMI) across 29 centers in …
Adding a low-dose blood thinner to standard heart attack drugs did not clearly prevent dangerous clots in the heart, based on a trial of 560…