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Oncology
RCT
Memantine improved neuropathy severity and pain scores versus placebo in CIPN over eight weeks.
Memantine eased nerve pain and tingling for chemotherapy patients in eight weeks
This randomized clinical trial enrolled 176 individuals with chemotherapy-induced peripheral neuropathy. Participants received memantine or …
A new trial found memantine significantly reduced nerve pain and tingling in chemotherapy patients compared to placebo over eight weeks.
Apr 29, 2026
Cardiology
RCT
Memantine reduced PAC burden and new-onset AF in a Phase 2 randomized trial of 241 adults.
Common Heart Flutters May Be Linked to Brain Drug
In this Phase 2 randomized, double-blind, placebo-controlled trial of 241 symptomatic adults with frequent PACs (≥1000/24 h), memantine show…
A new study shows a brain medication may calm frequent heart flutters and lower the risk of more serious heart rhythm problems.
Apr 22, 2026
Anesthesiology & Pain Medicine
RCT
Memantine reduces opioid use but not pain in knee osteoarthritis patients after surgery
This Common Memory Drug Cuts Opioid Use After Knee Replacement
A randomized controlled trial in adults with knee osteoarthritis found memantine did not significantly lower pain scores versus placebo, but…
A drug already approved for Alzheimer's disease may help knee replacement patients rely less on opioids during recovery — even if it does no…
Apr 14, 2026