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Home › Medications › paliperidone

paliperidone

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of paliperidone

12 trials tracked of paliperidone: 10 in phase 3 or 4 and 1 with published results. The most-cited published study has 72 citations.

12Trials tracked
10Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 7 Phase 3 3 Phase 2 2
  1. Phase 4 Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy Completed · 72 cited
  2. Phase 4 PaliperidoNe Extended-Release [ER] Dosing and Clinical Response in Acute Schizophrenia Completed
  3. Phase 4 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated Completed
  4. Phase 4 Efficacy Study of Paliperidone to Evaluate Subjective Change in Well-being and Drug Attitude in Schizophrenic Participants Completed
  5. Phase 4 Paliperidone Extended Release(ER) Effectiveness Study to Evaluate the Objective Symptom Change and Symptomatic Remission Completed
  6. Phase 4 Phase 4 Study to Evaluate Efficacy of Paliperidone Extended-Release(ER) in Schizophrenic Participants Completed
Show 6 more trials
  1. Phase 4 Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation Completed
  2. Phase 3 An Efficacy and Safety Study of Paliperidone Extended-Release (ER) Tablets in Participants With Schizophrenia Completed
  3. Phase 3 An Efficacy Study of Paliperidone for the Prevention of Relapse in Participants With Schizophrenia Completed
  4. Phase 3 An Open Label Multicentre Study to Determine the Dose Distribution of Paliperidone ER in Patients With Schizophrenia Completed
  5. Phase 2 A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication Completed
  6. Phase 2 Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder Completed

Showing the 12 most-cited and recently-updated of 12 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Paliperidone ER and LAI show no significant difference in personal and social performance scores
Psychiatry Meta-analysis
Paliperidone ER and LAI show no significant difference in personal and social performance scores Paliperidone Treatment Shows Improvement in Schizophrenia Social Performance
This meta-analysis of 20 RCTs and 38 single-arm trials indicates that both paliperidone ER and LAI significantly improve Personal and Social…
Paliperidone in both oral and injectable forms shows significant improvements in social and personal performance for people living with schi…
Sep 1, 2026
Case report review suggests LAI paliperidone stabilizes behavior in a 9-year-old with TBI over two years
Psychiatry Sys. Review
Case report review suggests LAI paliperidone stabilizes behavior in a 9-year-old with TBI over two years Long-acting shots help a boy control severe brain injury rage
This case report review describes a 9-year-old boy with severe traumatic brain injury and posttraumatic confusional state treated with long-…
A boy with severe brain injury rage found calm after months of failed pills, showing long-acting shots could help when daily medicine fails
Frontiers Apr 29, 2026
Planned trial compares injectable antipsychotics to usual care for psychosis with stimulant use
Psychiatry Phase III
Planned trial compares injectable antipsychotics to usual care for psychosis with stimulant use Hong Kong trial planned to test antipsychotic injections for substance use with psychosis
A trial record describes a planned phase 2/3 study of 165 individuals in Hong Kong with substance use disorders and psychosis.
Hong Kong researchers plan a trial to test long-acting antipsychotic injections for people with substance use disorders and psychosis.
CT.gov Apr 3, 2026