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Home › Medications › prednisone

prednisone

18 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of prednisone

295 trials tracked of prednisone: 102 in phase 3 or 4 and 54 with published results. The most-cited published study has 955 citations.

295Trials tracked
102Phase 3 & 4
0Recruiting
54With published results
Phase distribution
Phase 4 20 Phase 3 82 Phase 2 173 Phase 1 12 Other / NA 8
  1. Phase 3 A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis Completed · 955 cited
  2. Phase 3 Efficacy and Safety of Two Treatment Algorithms in Adults With Moderate to Severe Crohn's Disease Completed · 909 cited
  3. Phase 3 ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas Completed · 721 cited
  4. Phase 3 Efficacy and Safety of Adalimumab in Patients With Active Uveitis Completed · 653 cited
  5. Phase 3 Efficacy and Safety of Adalimumab in Subjects With Inactive Uveitis Completed · 508 cited
  6. Phase 3 Rituximab and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma Completed · 421 cited
Show 44 more trials
  1. Phase 3 Cabazitaxel Versus Docetaxel Both With Prednisone in Patients With Metastatic Castration Resistant Prostate Cancer Completed · 356 cited
  2. Phase 3 SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma Completed · 341 cited
  3. Phase 3 S0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone Metastases That Did Not Respond to Previous Hormone Therapy Completed · 333 cited
  4. Phase 3 Efficacy and Safety Study of Lenalidomide Plus R-CHOP Chemotherapy Versus Placebo Plus R-CHOP Chemotherapy in Untreated ABC Type Diffuse Large B-cell Lymphoma Completed · 268 cited
  5. Phase 3 Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed · 248 cited
  6. Phase 3 Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100 Completed · 247 cited
  7. Phase 3 Study Comparing Orteronel Plus Prednisone in Participants With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer Completed · 230 cited
  8. Phase 3 Study Comparing Orteronel Plus Prednisone in Participants With Metastatic Castration-Resistant Prostate Cancer. Completed · 230 cited
  9. Phase 4 Safety Study of Continued Enzalutamide Treatment In Prostate Cancer Patients Completed · 171 cited
  10. Phase 3 Thalidomide and Prednisone After Autologous Stem Cell Transplantation Multiple Myeloma Completed · 144 cited
  11. Phase 3 A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma Completed · 140 cited
  12. Phase 3 An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA) Completed · 131 cited
  13. Phase 3 Study of Pembrolizumab (MK-3475) Plus Olaparib Versus Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-7339-010/KEYLYNK-010) Completed · 131 cited
  14. Phase 3 Phase 3 Study of Carfilzomib, Melphalan, Prednisone vs Bortezomib, Melphalan, Prednisone in Newly Diagnosed Multiple Myeloma Completed · 129 cited
  15. Phase 4 Effectiveness in Daily Practice of Different Treatment Strategies for Early Rheumatoid Arthritis. Completed · 128 cited
  16. Phase 4 Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis Participants Completed · 125 cited
  17. Phase 3 Finding the Optimum Regimen for Duchenne Muscular Dystrophy Completed · 123 cited
  18. Phase 3 S9921, Hormone Therapy With or Without Mitoxantrone and Prednisone in Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer Completed · 111 cited
  19. Phase 3 TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial Completed · 102 cited
  20. Phase 3 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Completed · 84 cited
  21. Phase 3 A Trial of Antenatal Treatment of Alloimmune Thrombocytopenia Completed · 80 cited
  22. Phase 3 To Demonstrate Equivalence of Pharmacokinetics and Noninferiority of Efficacy for CT-P10 in Comparison With Rituxan Completed · 75 cited
  23. Phase 3 Study of Cyclosporine or Corticosteroids as an Adjunct to Plasma Exchange in Thrombotic Thrombocytopenic Purpura (TTP) Completed · 71 cited
  24. Phase 4 IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA Completed · 70 cited
  25. Phase 4 Cabazitaxel Versus the Switch to Alternative AR-targeted Agent (Enzalutamide or Abiraterone) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients Previously Treated With Docetaxel and Who Rapidly Failed a Prior AR-targeted Agent Completed · 65 cited
  26. Phase 3 GRAVITAS-301: A Study of Itacitinib or Placebo in Combination With Corticosteroids for Treatment of Acute Graft-Versus-Host Disease Completed · 59 cited
  27. Phase 3 Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma Completed · 59 cited
  28. Phase 3 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Completed · 57 cited
  29. Phase 3 Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD) Completed · 52 cited
  30. Phase 3 Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921) Completed · 49 cited
  31. Phase 3 Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Completed · 48 cited
  32. Phase 3 Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed · 46 cited
  33. Phase 3 Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed · 36 cited
  34. Phase 4 Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study Completed · 35 cited
  35. Phase 4 Tocilizumab Plus a Short Prednisone Taper for GCA Completed · 33 cited
  36. Phase 3 A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM) Completed · 32 cited
  37. Phase 3 Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease Completed · 32 cited
  38. Phase 3 Chemotherapy After Prostatectomy (CAP) For High Risk Prostate Carcinoma Completed · 29 cited
  39. Phase 3 A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC) Completed · 29 cited
  40. Phase 3 A Study of PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma Completed · 25 cited
  41. Phase 3 Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer Completed · 20 cited
  42. Phase 3 Methotrexate and Mycophenolate Mofetil for UVEITIS Completed · 18 cited
  43. Phase 3 Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma Completed · 17 cited
  44. Phase 3 Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma Completed · 17 cited

Showing the 50 most-cited and recently-updated of 295 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Attenuated R-THP-COP regimen achieved complete response in an 85-year-old with diffuse large B-cell lymphoma
Oncology Sys. Review
Attenuated R-THP-COP regimen achieved complete response in an 85-year-old with diffuse large B-cell lymphoma Attenuated R-THP-COP regimen shows promise for elderly diffuse large B-cell lymphoma
This case report describes an 85-year-old female patient with diffuse large B-cell lymphoma treated with an attenuated R-THP-COP regimen. Th…
An 85-year-old woman achieved complete radiological response and remained symptom-free for three years on an attenuated chemotherapy regimen…
Frontiers Jun 2, 2026
Meta-analysis of double-expressor lymphoma prognoses and novel therapies
Infectious Disease Meta-analysis
Meta-analysis of double-expressor lymphoma prognoses and novel therapies Double-expressor lymphoma linked to worse survival outcomes in large study
This systematic evaluation meta-analysis of 9,808 patients with diffuse large B-cell lymphoma found double-expressor lymphoma (DEL) is assoc…
A major review finds double-expressor lymphoma patients have worse survival. New drug combinations show promise for better results.
Frontiers May 22, 2026
Tucidinostat plus R-CHOP improves outcomes in MYC/BCL2 double-expressor DLBCL
Oncology RCT
Tucidinostat plus R-CHOP improves outcomes in MYC/BCL2 double-expressor DLBCL New drug tucidinostat improves outcomes for high-risk lymphoma patients
A phase 3 trial found adding oral tucidinostat to R-CHOP significantly improved event-free survival and complete response rates in patients …
A large trial shows adding tucidinostat to standard chemo lowers disease risk and improves survival for patients with aggressive lymphoma.
JAMA May 19, 2026
Ibrutinib plus chemo without ASCT shows survival benefit in mantle cell lymphoma
Oncology RCT
Ibrutinib plus chemo without ASCT shows survival benefit in mantle cell lymphoma Adding stem cell transplant to ibrutinib treatment offered no extra benefit for lymphoma patients
In younger patients with mantle cell lymphoma, adding ASCT to an ibrutinib regimen did not improve outcomes but increased toxicity. Ibrutini…
Adding stem cell transplant to ibrutinib did not improve survival for younger lymphoma patients but increased side effects.
May 16, 2026
Songjiao Dihuang Tang for Immune Checkpoint Inhibitor-Associated Myocarditis: Trial Protocol
Drug Pipeline RCT
Songjiao Dihuang Tang for Immune Checkpoint Inhibitor-Associated Myocarditis: Trial Protocol Chinese herbal formula tested for immunotherapy heart side effect
This protocol describes a multicenter, double-blind RCT of Songjiao Dihuang Tang plus standard care vs placebo in 200 patients with mild ICI…
A new trial will test if a traditional Chinese herbal formula can protect cancer patients from a rare but serious heart complication caused …
Frontiers May 16, 2026
Mycophenolate mofetil non-inferior to prednisone for first-episode nephrotic syndrome in children
Pediatrics RCT
Mycophenolate mofetil non-inferior to prednisone for first-episode nephrotic syndrome in children Mycophenolate Mofetil Offers Alternative to Steroids for Nephrotic Syndrome
This phase 3 non-inferiority trial randomized 272 children aged 1-10 years with first-episode steroid-sensitive nephrotic syndrome to mycoph…
A new trial shows mycophenolate mofetil works as well as prednisone for children with nephrotic syndrome, with fewer steroid side effects.
May 1, 2026
Modified prednisone regimen shows short-term ineffectiveness in infantile epileptic spasms syndrome based on retrospective cohort data
Allergy & Immunology Cohort
Modified prednisone regimen shows short-term ineffectiveness in infantile epileptic spasms syndrome based on retrospective cohort data Blood marker may predict prednisone response in infantile spasms
This retrospective cohort study evaluated 66 IESS patients and 53 age-matched healthy controls.
A blood protein called HMGB1 may help doctors quickly tell if prednisone will work for infantile spasms.
Frontiers May 1, 2026
Niraparib plus abiraterone and prednisone shows mixed results in HRR-mutated mCRPC
Drug Pipeline Cohort
Niraparib plus abiraterone and prednisone shows mixed results in HRR-mutated mCRPC New drug combo extends life for some prostate cancer patients
This retrospective cohort study of 5 patients with HRR-mutated metastatic castration-resistant prostate cancer evaluated niraparib plus abir…
Some men with advanced prostate cancer are living longer with a powerful new drug combo, even when they’re older or too weak for harsh treat…
Frontiers Apr 28, 2026
Low-dose IVIG shows similar efficacy to standard-dose IVIG in adults with AChR-positive generalized myasthenia gravis
Neurology Cohort
Low-dose IVIG shows similar efficacy to standard-dose IVIG in adults with AChR-positive generalized myasthenia gravis Low-Dose IVIG Works as Well as High-Dose for MG
This prospective single-center cohort study evaluated low-dose versus standard-dose intravenous immunoglobulin (IVIG) in 34 adults with AChR…
A much smaller dose of IVIG may relieve severe muscle weakness in myasthenia gravis just as well as the standard high dose—cutting treatment…
Frontiers Apr 28, 2026
Case Report Describes Treatment of Severe Mosquito Bite Allergy and EBV-Associated NK-Cell Lymphoproliferative Disorder
Allergy & Immunology Sys. Review
Case Report Describes Treatment of Severe Mosquito Bite Allergy and EBV-Associated NK-Cell Lymphoproliferative Disorder Why a 70-Year-Old Man’s Mosquito Bites Turned Deadly
This case report details the clinical management of a 70-year-old male with severe mosquito bite allergy and EBV-associated NK-cell lymphopr…
A single mosquito bite can sometimes signal a hidden immune problem, especially in older adults.
Frontiers Apr 23, 2026
Combined Therapy for Febrile Ulceronecrotic Mucha-Habermann Disease in Young Children: Case Report and Review
Pediatrics Sys. Review
Combined Therapy for Febrile Ulceronecrotic Mucha-Habermann Disease in Young Children: Case Report and Review Doctors Heal Rare Skin Condition in Toddler Using Drug Combo
This publication is a case report and literature review focusing on Febrile ulceronecrotic Mucha-Habermann disease in preschool-aged childre…
A rare and painful skin disease in young children may now have a clearer path to recovery.
Frontiers Apr 23, 2026
Mitoxantrone liposome plus CMOP shows high response rates in untreated peripheral T-cell lymphoma patients
Oncology Phase I
Mitoxantrone liposome plus CMOP shows high response rates in untreated peripheral T-cell lymphoma patients New Drug Combo Helps Most Patients With Hard-to-Treat Lymphoma
This phase 1b multicenter clinical trial evaluated mitoxantrone hydrochloride liposome combined with cyclophosphamide, vincristine, and pred…
A new drug combo wrapped in fat bubbles helped 89% of patients with hard-to-treat lymphoma shrink tumors without causing deaths.
Apr 12, 2026

All prednisone Articles