Acupuncture Plus Antidepressants Lowers HAMD Scores in Chinese Depression Patients
Acupuncture combined with antidepressants may improve depression scores
In a network meta-analysis of 7,031 patients in China, adding acupuncture to SSRIs or SNRIs reduced HAMD depression scores more than SSRI mo…
Combining acupuncture with standard antidepressants may lead to greater reductions in depression scores than using antidepressants alone.
Antidepressant use is associated with a 1.34 increased risk of ventricular arrhythmia and sudden cardiac death
Antidepressant use linked to higher risk of sudden cardiac death
This meta-analysis of 9,619,278 patients found that antidepressant use, including SSRIs and TCAs, is associated with a significantly increas…
A massive study of over 9 million people shows a link between antidepressant use and a higher risk of serious heart rhythm problems.
Lower baseline IL-2 and IL-6 levels signal potential antidepressant treatment response in Major Depressive Disorder
Specific markers may help predict response to depression medication
This meta-analysis of baseline peripheral inflammatory biomarkers in adults with Major Depressive Disorder found no significant difference i…
New data suggests that certain inflammatory markers in the blood could help predict which patients will respond to common antidepressants.
Adding Chinese patent medicines to SSRIs improves HAMD scores and response rates in depressive disorder
Chinese Herbal Add-Ons May Boost Antidepressant Effects
This systematic review and network meta-analysis of 5,975 patients found that seven Chinese patent medicine (CPM) combinations with SSRIs si…
Adding certain Chinese patent medicines to standard antidepressants improved depression scores and response rates in a new analysis.
Early Emotional Interventions Boost Stroke Recovery Outcomes
Early Emotional Care After Stroke Boosts Recovery
Meta-analysis of 12,020 patients shows early emotional interventions improve Barthel Index scores, with best results when started within 2 w…
Starting emotional support within 2 weeks of a stroke may improve daily function more than waiting, a new analysis finds.
No significant association between BDNF genotypes and remission in major depressive disorder patients treated with antidepressants
Genetic markers do not predict antidepressant success in major depression
This meta-analysis review examined 599 Caucasian patients with a major depressive episode treated with SSRIs, SNRIs, or TCAs. The analysis f…
A large review found that specific genetic markers do not predict who will recover from depression when taking common antidepressant medicat…
Genotype-Guided SSRI Prescribing Shows No Short-Term Benefit but Higher Remission at 6 Months
Genetic Testing Helps Some Depression Patients Feel Better Long Term
This randomized clinical trial compared genotype-guided SSRI prescribing to usual care in 1460 patients with depression. At 3 months, there …
• Genetic-guided SSRI prescriptions boost six-month remission rates for certain patients • Helps people with specific gene variations affect…
Adjunctive JNJ-42165279 fails to improve depression in SSRI/SNRI inadequate responders
Early trial finds new drug did not help depression in patients already on antidepressants
This phase 2a double-blind RCT tested adjunctive JNJ-42165279 25 mg daily versus placebo in 153 adults with major depressive disorder with a…
A small early study found a new drug did not improve depression symptoms for patients already taking standard antidepressants.
Meta-analysis identifies two genomic loci associated with antidepressant non-response in 135,471 individuals
Why do antidepressants fail for some people? New genetic clues emerge
A genome-wide association meta-analysis of 135,471 individuals prescribed antidepressants identified two novel genomic loci associated with …
Millions struggle to find working antidepressants, but new genetic data reveals why some fail and suggests other drug options for treatment …