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Home › Medications › vitamin E

vitamin E

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of vitamin E

7 trials tracked of vitamin E: 5 in phase 3 or 4 and 2 with published results. The most-cited published study has 50 citations.

7Trials tracked
5Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 1 Phase 3 4 Phase 2 2
  1. Phase 3 S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000 Completed · 50 cited
  2. Phase 3 S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000 Completed · 3 cited
  3. Phase 4 Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis Completed
  4. Phase 3 S0000 Selenium and Vitamin E in Preventing Prostate Cancer Completed
  5. Phase 3 Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer Completed
  6. Phase 2 Trental & Vitamin E for Radiation-Induced Fibrosis Completed
Show 1 more trials
  1. Phase 2 Vitamin E Dosing Study Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Cochrane review finds uncertain benefits of drugs for Friedreich ataxia with low-certainty evidence
Cardiology Sys. Review
Cochrane review finds uncertain benefits of drugs for Friedreich ataxia with low-certainty evidence Cochrane review finds little benefit for drugs treating Friedreich ataxia
This Cochrane systematic review evaluated pharmacological treatments for people with genetically-confirmed Friedreich ataxia. The analysis i…
A major review of eight studies found that most drugs for Friedreich ataxia likely make little difference to key symptoms compared to placeb…
Cochrane May 16, 2026
Ketotifen shows significant improvements in hepatic steatosis and fibrosis indices compared with vitamin E in a pilot study of NAFLD
Gastroenterology RCT
Ketotifen shows significant improvements in hepatic steatosis and fibrosis indices compared with vitamin E in a pilot study of NAFLD Ketotifen beats Vitamin E for fatty liver disease in new trial
This randomized pilot study enrolled 60 individuals with non-alcoholic fatty liver disease (NAFLD) and followed them for 6.0 months.
New research shows a common allergy medicine reduces liver fat and scarring more effectively than Vitamin E for people with fatty liver dise…
Apr 27, 2026
Narrative review examines antioxidant metabolites for autism spectrum disorder in children
Drug Pipeline Sys. Review
Narrative review examines antioxidant metabolites for autism spectrum disorder in children Could antioxidant nutrients help children with autism spectrum disorder?
This narrative review evaluates the potential role of antioxidant metabolites from botanical drugs and nutrients, including vitamins E and C…
Antioxidant nutrients like vitamins E and C, plus botanical compounds, may help address oxidative stress linked to autism spectrum disorder …
Frontiers Apr 19, 2026
Oxidative stress drives steroid-induced necrosis of femoral head; antioxidants may help maintain redox balance
Orthopedics & Sports Medicine Sys. Review
Oxidative stress drives steroid-induced necrosis of femoral head; antioxidants may help maintain redox balance Why Steroid Pills Can Quietly Starve Your Hip Bone
This systematic review examined the role of oxidative stress and various antioxidant classes in steroid-induced necrosis of the femoral head…
Steroid pills used for asthma and lupus may quietly starve hip bones of blood through oxidative stress, potentially leading to bone death an…
Frontiers Apr 13, 2026
Phase 2 trial tests three Vitamin E doses versus placebo in 200 adults with NAFLD
Gastroenterology Phase II
Phase 2 trial tests three Vitamin E doses versus placebo in 200 adults with NAFLD Vitamin E dosing study in 200 adults with fatty liver disease completes trial
A phase 2 randomized controlled trial enrolled 200 adults with NAFLD to compare three doses of Vitamin E (200 IU, 400 IU, 800 IU) with place…
A completed trial on Vitamin E for fatty liver disease has finished, but the results showing if the doses helped or caused harm are not yet …
CT.gov Mar 30, 2026