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Home › Conditions › Friedreich ataxia

Friedreich ataxia

Part of Hereditary ataxia

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Friedreich ataxia

10 trials tracked for Friedreich ataxia: 2 in phase 3 or 4.

10Trials tracked
2Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 3 1 Phase 2 6 Other / NA 2
  1. Phase 4 An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich Ataxia Completed
  2. Phase 3 A Study to Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich Ataxia Completed
  3. Phase 2 Interferon Gamma-1b in Friedreich Ataxia (FRDA) Completed
  4. Phase 2 FRDA Investigator Initiated Study (IIS) With Elamipretide Completed
  5. Phase 2 Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia Completed
  6. Phase 2 Efficacy of EGb761 in Patients Suffering From Friedreich Ataxia Completed
Show 4 more trials
  1. Phase 2 NAD+ Precursor Supplementation in Friedreich's Ataxia Completed
  2. Phase 2 A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia Completed
  3. N/A Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia Completed
  4. N/A Neurology Measures in FA Children Completed

Showing the 10 most-cited and recently-updated of 10 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Cochrane review finds uncertain benefits of drugs for Friedreich ataxia with low-certainty evidence
Cardiology Sys. Review
Cochrane review finds uncertain benefits of drugs for Friedreich ataxia with low-certainty evidence Cochrane review finds little benefit for drugs treating Friedreich ataxia
This Cochrane systematic review evaluated pharmacological treatments for people with genetically-confirmed Friedreich ataxia. The analysis i…
A major review of eight studies found that most drugs for Friedreich ataxia likely make little difference to key symptoms compared to placeb…
Cochrane May 16, 2026
Longitudinal multimodal MRI identifies Friedreich ataxia progression subtypes in 111 patients and controls
Neurology Cohort
Longitudinal multimodal MRI identifies Friedreich ataxia progression subtypes in 111 patients and controls Three distinct brain patterns linked to Friedreich ataxia progression
This observational cohort study analyzed 111 participants, including 54 Friedreich ataxia patients and 57 controls, using longitudinal multi…
Three distinct brain patterns linked to Friedreich ataxia progression were identified using MRI scans and genetic data in patients.
medRxiv Apr 23, 2026

Research across Hereditary ataxia

Related studies from across the Hereditary ataxia family.

Nicotinamide Riboside Plus Exercise Improves Fitness in Friedreich's Ataxia
Pediatrics RCT
Nicotinamide Riboside Plus Exercise Improves Fitness in Friedreich's Ataxia Combining exercise and nicotinamide riboside improved fitness in Friedreich's ataxia patients
This phase 2 randomized trial in 66 individuals with Friedreich's ataxia found that 12 weeks of nicotinamide riboside plus exercise increase…
A 12-week trial found that combining exercise with nicotinamide riboside improved heart and lung fitness in people with Friedreich's ataxia.
May 1, 2026
Home-Based Core Stability Telerehabilitation Shows Feasibility for Hereditary Ataxia
Physical Medicine & Rehab RCT
Home-Based Core Stability Telerehabilitation Shows Feasibility for Hereditary Ataxia Home-based exercises may help people with hereditary ataxia improve walking and balance confidence
This single-blind pilot RCT tested a home-based core stability exercise telerehabilitation program in 12 individuals with hereditary ataxia.
A small pilot study found that home-based stability exercises improved walking and balance confidence for people with hereditary ataxia, tho…
May 1, 2026