HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Diabetes & Endocrinology
Cohort
Elevated free and bioavailable testosterone linked to non-alcoholic fatty liver disease risk in postmenopausal women
High Free Testosterone Levels May Worsen Liver Disease In Older Women
This prospective cohort study examined 1,705 postmenopausal women over 5,269 person-years. Higher concentrations and percentages of free tes…
High levels of free testosterone in older women may signal a higher risk of developing or worsening fatty liver disease.
Frontiers
Apr 29, 2026
Genetics & Precision Medicine
Sys. Review
Review of scRNA-seq applications in non-alcoholic fatty liver disease and hepatocellular carcinoma research
New sequencing tools map liver disease across many species
This narrative review examines the use of single-cell and single-nucleus RNA sequencing in models of non-alcoholic fatty liver disease, fibr…
Scientists used advanced sequencing to study liver disease in humans and animals. This review maps how the disease changes at a cellular lev…
Frontiers
Apr 28, 2026
Gastroenterology
RCT
Ketotifen shows significant improvements in hepatic steatosis and fibrosis indices compared with vitamin E in a pilot study of NAFLD.
Ketotifen beats Vitamin E for fatty liver disease in new trial
This randomized pilot study enrolled 60 individuals with non-alcoholic fatty liver disease (NAFLD) and followed them for 6.0 months. Partici…
New research shows a common allergy medicine reduces liver fat and scarring more effectively than Vitamin E for people with fatty liver dise…
Apr 27, 2026
Rheumatology
Sys. Review
Narrative Review Suggests Electroacupuncture May Benefit NAFLD with Minimal Side Effects
Electroacupuncture shows promise for non-alcoholic fatty liver disease.
This narrative review summarizes evidence on electroacupuncture for non-alcoholic fatty liver disease (NAFLD). The authors suggest potential…
A review suggests electroacupuncture may help treat non-alcoholic fatty liver disease with minimal side effects, offering a new option for p…
Frontiers
Apr 24, 2026
Rheumatology
Sys. Review
Systematic review links periodontitis to NAFLD progression and HCC risk
Your Mouth Could Be Harming Your Liver—Here’s What to Do
This systematic review finds that periodontitis and oral pathogens like F. nucleatum are independent risk factors for NAFLD progression, cir…
You brush your teeth every day. You might floss sometimes.
Frontiers
Apr 23, 2026
Nutrition & Obesity Medicine
Sys. Review
Narrative review covers IBD, bile acid malabsorption, IBS-D, CRC, obesity, NAFLD, and sepsis-related intestinal injury.
This narrative review discusses bile acid malabsorption and related digestive conditions.
This narrative review examines a broad spectrum of gastrointestinal conditions, including inflammatory bowel disease, bile acid malabsorptio…
Bile acids act as powerful signaling molecules that control gut health, metabolism, and immune responses through a complex network of recept…
Frontiers
Apr 21, 2026
Drug Pipeline
Sys. Review
Literature review synthesizes Schisandra chinensis effects on gut microbiota and metabolic pathways across multiple conditions.
This Ancient Berry May Quiet Inflammation From Your Gut to Your Brain
This literature review examines the potential of Schisandra chinensis regarding gut health and metabolic regulation. The authors synthesize …
An ancient berry used for centuries may rebalance gut bacteria to calm inflammation linked to digestive issues, liver disease, diabetes, and…
Frontiers
Apr 19, 2026
Drug Pipeline
Meta-analysis
Systematic review and meta-analysis of puerarin in experimental non-alcoholic fatty liver disease models
Puerarin May Shield the Liver — Here’s How
This systematic review and meta-analysis evaluated puerarin treatment in 331 animals across experimental non-alcoholic fatty liver disease m…
A natural compound from kudzu root slashes liver fat and inflammation in animal studies, offering hope for millions with fatty liver disease…
Frontiers
Apr 18, 2026
Pediatrics
Cohort
Adipose-inflammatory factors elevated in obese children, correlate with metabolic health and NAFLD severity
Hidden Inflammation in Healthy-Weight Obese Kids
A retrospective cohort study of 500 obese children and 162 lean controls found that levels of leptin, resistin, RBP-4, PGRN, TNF-α, IL-6, an…
Obese children with normal blood sugar still face hidden liver inflammation that current tests often miss, revealing a dangerous risk in pla…
Frontiers
Apr 10, 2026
Diabetes & Endocrinology
RCT
Walking program improves liver enzymes and BMI in children with PKU and NAFLD
Walking program shows improvement in liver health markers for children with PKU and fatty liver
An 8-week RCT in 40 overweight/obese children with PKU and NAFLD found that a free walking program significantly improved BMI, ALT, GGT, ALP…
An 8-week walking program improved liver health markers and BMI in children with PKU and fatty liver disease.
Apr 3, 2026
Gastroenterology
Meta-analysis
High Dietary Inflammatory Index Linked to Increased NAFLD Risk (OR 1.33, CI 1.23-1.44)
Could Your Diet Be Fueling Fatty Liver Disease?
Meta-analysis of 262,468 participants shows high Dietary Inflammatory Index (DII) significantly increases risk of NAFLD (OR 1.33, 95% CI: 1.…
A high-inflammation diet is strongly linked to fatty liver disease and liver scarring in a review of over 262,000 people.
Mar 27, 2026