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Cardiology
Meta-analysis
DOACs reduce stroke, mortality, and major bleeding risk compared to vitamin K antagonists in hemodialysis
DOACs Show Lower Stroke and Bleeding Risk in Dialysis Patients
This meta-analysis evaluated the efficacy and safety of direct oral anticoagulants (DOACs) compared to vitamin K antagonists in patients wit…
Patients with atrial fibrillation on hemodialysis may have lower risks of stroke and major bleeding when using DOACs instead of vitamin K an…
Sep 1, 2026
Cardiology
Meta-analysis
DOACs associated with lower risks of recurrent ICH, ischemic stroke, and mortality in atrial fibrillation
Trial Shows Direct Oral Anticoagulants Reduce Risks for Atrial Fibrillation
This meta-analysis evaluates the efficacy of direct oral anticoagulants (DOACs) compared to vitamin K antagonists (VKAs) in patients with at…
New data suggests that direct oral anticoagulants may lower the risk of stroke and bleeding for patients with atrial fibrillation.
Aug 22, 2026
Cardiology
Meta-analysis
Direct oral anticoagulants reduce thrombotic events and major bleeding in cirrhosis with atrial fibrillation or venous thromboembolism
Direct oral anticoagulants show promise for patients with liver cirrhosis
A meta-analysis of predominantly observational studies compared direct oral anticoagulants with traditional anticoagulants in patients with …
New analysis suggests direct oral anticoagulants may reduce blood clots and major bleeding risks for patients with liver cirrhosis and heart…
Aug 1, 2026
Cardiology
Meta-analysis
Network meta-analysis compares DOACs and VKAs for intracranial hemorrhage risk
Dabigatran may be safest for brain bleeding risk
This network meta-analysis of 127,267 patients with venous thromboembolism or atrial fibrillation found that all DOACs had lower risk of int…
All blood thinners beat warfarin for brain bleed risk, but dabigatran may be the safest choice.
Frontiers
May 19, 2026
Cardiology
Meta-analysis
DOACs versus VKAs for left ventricular thrombus management in adults
Newer Blood Thinners May Be Safer for Heart Clot Patients
A meta-analysis suggests DOACs may be a reasonable alternative to VKAs for left ventricular thrombus, with similar efficacy and potentially …
If you have a blood clot in your heart, newer blood thinners may be just as effective as warfarin with a lower risk of dangerous bleeding.
Frontiers
May 14, 2026
Drug Pipeline
Meta-analysis
Network meta-analysis compares prophylactic anticoagulants for central venous catheter-related thrombosis in cancer patients
Cancer Patients May Avoid Clots With Safer Blood Thinner
This network meta-analysis synthesizes data from 19 clinical studies regarding prophylactic anticoagulation in cancer patients with central …
A new analysis shows one specific blood thinner may protect cancer patients from dangerous clots with fewer side effects.
Frontiers
Apr 19, 2026
Pediatrics
RCT
Apixaban alters hemostatic biomarkers in children with heart disease compared to standard care
New Blood Test Shows Apixaban Works Safely in Kids
This exploratory biomarker substudy of an RCT in children over one year with heart disease assessed apixaban versus standard care (vitamin K…
A new blood test confirms apixaban works safely for children with heart disease, offering a simpler alternative to painful injections and fr…
Apr 10, 2026