N/A N=31 Gastrointestinal Hormonal Regulation of Obesity
Obesity
Primary: Change in Body Weight From Baseline to 12 Months — 1.09; 1.55 lbs
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=8 The Effect of Macronutrients on Satiety and Gut Hormone Responses
Eating Behavior
Primary: The Effect of Proteins on the Secretion of Gut Hormones From Different Parts of the Gastrointestinal Tract — 1310; 1073; 1118; 1188 pg*min/mL
N/A N=30 Neuroendocrine Modulation of Metabolic Effects in Overweight Adolescents
Obesity
Primary: Peak Growth Hormone (GH) on the GH Stimulation Test — 40.1; 25.2 ng/ml — p=<0.05
N/A N=61 Eating Behaviour in Crohn's Disease
Crohn's Disease
Primary: Dietary Recalls (Calorific Intake) — 1900.9; 2054.3 kcal
N/A N=24 Growth Hormone as a Determinant of Weight Regulation
Obesity
Primary: 24 Hour Average Plasma Growth Hormone Concentration — 0.4; 1.2; 4.1 ng/mL
N/A N=16 The Role of Altered Nutrient Partitioning in Food Reward
Overweight and Obesity
Primary: Change in Preference- Liking — 6.5; 4.5 units on a scale
N/A N=21 Protein Quality on Appetite Control, Reward-driven Eating, & Subsequent Food Intake
Appetite and General Nutritional Disorders
Primary: Eating Initiation — 250; 270; 245; 250 minutes
Phase 2 N=24 Leptin in the Maintenance of Reduced Body Weight
Obesity
Primary: Percent Change From Baseline in Body Weight at 6 Months — 10.2; 12.7 percentage change
N/A N=29 Exendin-9,39 and Satiety After Bariatric Surgery
Obesity
Primary: Caloric Intake — 531; 465; 444; 494 calories
N/A N=12 Effect of Palm Olein Intake on Lipid Profile and Appetite Regulation
Lipidaemia
Primary: Change From Baseline in Appetite Hormones PYY — 58.5; 60; 56 mmol/L*min
N/A N=46 Activity, Adiposity, and Appetite in Adolescents 2
Obesity · Metabolic Disease · Insulin Sensitivity
Primary: Appetite- Subjective — 9239.4; 7879.6; 6130.5; 8970.0 score on a scale*min
N/A N=42 The Impact of Snacks Which Vary Nutritionally in Their Satiating Potential on Measures of Appetite Control
Lack of Satiety · Hyperphagia
Primary: Test Meal Energy Intake — 1007.3; 1019.6; 1143.4 kcal — p=<0.01
N/A N=5 Gastrectomy, Eating Behaviour and GLP-1
Gastric Cancer · Dumping Syndrome
Primary: Nadir Blood Glucose — 3; 4.4 mmol/l — p=0.008
N/A N=255 Promoting The Self-Regulation Of Energy Intake
Obesity
Primary: Children's BMI Percentiles — 49; 41; 15; 18 Participants — p=<0.05
Phase 1 N=96 GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight
Obesity
Primary: Change in Craving Score — -0.7; -0.3 score — p=< 0.001
Phase 1 N=12 In Vivo Leptin Signaling in Humans After Acute Leptin Administration
Lean · Obese · Obese Diabetics
Primary: Leptin Signaling — 3.1 fold change
N/A N=38 Effect of Snacks on Appetite Control
Healthy Canadians · Appetite Control
Primary: Total Area Under the Curve (AUC) for Hunger, Fullness, Desire to Eat and Prospective Consumption Using Visual Analog Scales (VAS) — 651; 1008; 638; 640 cm x min — p=<0.05
Phase 2 N=41 Biology and Experience of Eating in Women With Obesity
Obesity
Primary: Number of Participants Who Reported Nausea at 10 Minutes Post Treatment — 17; 18 Participants
Phase 3 N=55 Examination of Bromocriptine on Homeostatic and Hedonic Mechanisms of Food Intake in Individuals at High Risk for T2DM
Overweight and Obesity · Eating Behavior
Primary: Ad Libitum Food and Beverage Intake (g) — 71.5; 81.9; 24.9; 33.6 g — p=0.45
N/A N=28 Effect of Oligofructose on Appetite in Overweight Subjects
Appetite Regulation · Obesity
Primary: Subjective Appetite Ratings in Hunger Compared to Baseline — 4.8; 3.6; 3.6; 4.1 cm — p=0.135
N/A N=39 The Effect of Protein-enriched Diet on Body Composition and Appetite
Overweight · Obese · Metabolic Syndrome
Primary: Change in Lipid Content of the Liver (Intrahepatocellular Lipid) — 27.9; 9.3; 21.4; 5.9 % IHCL — p=<0.05
N/A N=32 Appetite Suppression Trial With Polydextrose
Body Weight · Non-restrained Eaters
Primary: Energy Intake at an ad Libitum Lunch on a Test-day in Normal Weight and Overweight Women. — 2694; 2537; 2317; 2335 kJ — p=0.2918
N/A N=15 Cancer Anorexia and the Central Nervous System
Cancer Cachexia
Primary: ACTIVATION/NON ACTIVATION OF SPECIFIC BRAIN AREAS, EVALUATED BY FUNCTIONAL MAGNETIC RESONANCE — 585.57; 667.92; 511.22 BOLD
N/A N=71 Learning to Love Mealtime Together
Infant Obesity · Parenting · Feeding Behavior
Primary: Infant Weight-for-Length Z Scores — 0.43; 0.12 z-score — p=0.07
Phase 2 N=10 Ghrelin in Healthy and Frail Older Women
Frailty
Primary: Kilocalories Consumed — 412; 553 Kilocalorie
Phase 1 N=12 A First-Time-in-Human Study to Assess the Safety and Tolerability of PP 1420 in Healthy Subjects
Obesity
Primary: Number of Subjects With Adverse Events (AEs) — 2; 5; 3; 2 Participants
N/A N=26 Fatty Acid Oxidation Disorders & Body Weight Regulation Grant
Trifunctional Protein Deficiency
Primary: An Outcome of This Study is the Difference in Percent Body Fat (%BF) Between Subjects With a Long-chain Fatty Acid Oxidation Disorder and Normal Controls. — 31.8; 27.2…
Phase 2 N=40 Effect of GLP-1 Analogue ROSE-010 on Appetite in Overweight and Obese Subjects
Obesity; Overweight
Primary: Food Consumption — 605.5; 404.3; 423.6 weight food eaten g
N/A N=187 Modifiable Predictors of Neural Vulnerabilities for Obesity
Obesity
Primary: Caudate Activation for Sip Cue — -0.026264341 activation beta value
N/A N=16 The Effect of Hydration Status on Glycemic Control and Appetite Regulation
Healthy
Primary: Glycemic Response — 303; 306 mmol*120 min*l-1 — p=0.886