N/A N=38 Measurements of Angulation of the C-spine
Cervical Spine
Primary: Measurements of Angulation of the Neck (C-spine) on MRI Scans — 10.6; 21.6; 5.5; 4.1 degrees — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=10 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain
Neck Pain
Primary: Occiflex Device Safety — 26 Number of adverse effects
N/A N=19 Driving After Cervical Spine Surgery
Cervical Disc Disease
Primary: Change in Number of Total Collisions (TC) — 2 collisions/crashes
N/A N=20 Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
Vertebral Artery Dissection · Cerebrovascular Accident · Stroke
Primary: Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation — 15.5; 15.1; 14.7 cm/s
N/A N=8 Postural Stability in Cervical Spinal Myelopathy
Cervical Spondylotic Myelopathy
Primary: Virtual Environment TBI System (VETS) Assessment of Static Posturography — 11; 13.0; 48.4; 19.1 Square Centimeters
N/A N=710 INFUSE® Bone Graft/ PEEK Interbody Spacer/ Anterior Cervical Plate Pivotal Clinical Trial
Degenerative Disc Disease
Primary: Rate of Overall Success — 80.9; 59.9 percentage of participants — p=<0.001
N/A N=575 LDR Spine USA Mobi-C(R) Cervical Disc Prosthesis IDE
Degenerative Disc Disease
Primary: Composite Definition of Study Success — 65.3; 73.7; 37.4; 69.7 percentage of subjects analyzed — p=0.0021
N/A N=30 Cervical Activation During Elastic and Manual Resistance
Cervical Pain
Primary: Percent of Peak Activation (%PA) — 51.72; 61.20; 88.1; 80.80 Percentage of Peak Activation (%PA)
N/A N=20 Dispersal Pattern for Spine Injections (Gadolinium Contrast)
Cervical Radiculopathy
Primary: Injection Dispersal Patterns Measured (in cm) in the Superoinferior Directions on Post-injection MRI With a Calibrated Internal Measurement Software. — 14.73 cm
N/A N=30 Clavicle Splint for Pain Reduction After Posterior Cervicothoracic Surgery
Posterior Cervical Surgery · Posterior Cervical Fusion · Posterior Cervical Laminectomy
Primary: Average Neck Pain Level — 1; 1 units on a scale (VAS pain scale)
N/A N=104 Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Radiating Pain · Myelopathy · Cervicobrachial Syndrome
Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641
N/A N=22,430 Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool
Cervical Spine Injury
Primary: Cervical Spine Injury — 274; 159 Participants — p=.05
N/A N=118 ViBone in Cervical and Lumbar Spine Fusion
Spondylosis · Cervical Spondylosis · Spondylolisthesis
Primary: Fusion Rates Per Level Using the Bridwell Interbody Grading Scale — 64; 50 Fusions
Phase 4 N=79 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Radicular; Neuropathic, Cervical · Neck Pain
Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23
N/A N=4,034 Evaluation of the Safety of C-Spine Clearance by Paramedics
Fracture of Cervical Spine
Primary: Adverse Events — 1 Adverse event
N/A N=397 Study of the Safety and Effectiveness of the Artificial Cervical Disc - Low Profile Device at Two Adjacent Levels
Cervical Degenerative Disc Disease · Radiculopathy · Myelopathy
Primary: Rate of Overall Success — 81.4; 69.4 percentage of participants — p=1.000
N/A N=231 Outcome Study of Patients Treated With Translational Cervical Plate Used to Treat Degenerative Disc Disease
Degenerative Disc Disease
Primary: Radiographic Fusion — 66; 46; 37; 75 percentage of subjects
N/A N=352 Investigation of the Two Level Simplify® Cervical Artificial Disc
Cervical Degenerative Disc Disorder
Primary: Composite Clinical Success (CCS) Rate of the Simplify® Disc — 153; 105 Participants — p=0.017
Phase 3 N=545 Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDD
Cervical Degenerative Disc Disease
Primary: Rate of Overall Success — 70.4; 63.2 percentage of participants — p=0.995
N/A N=805 A Pragmatic Evaluation of the Canadian C-Spine Rule by Paramedics
Neck Injuries
Primary: Proportion of Patients Transported With Spinal Immobilization — 1334; 813 Participants — p=0.0007
Phase 4 N=65 Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain
Pain, Radiating
Primary: Avoidance of Neck Surgery — 24; 20; 3; 6 Participants
N/A N=28 The Effect of Manipulation of the Cervical Spine on Pain Biomarkers
Neck Pain, Posterior
Primary: Plasma Concentration of Oxytocin — 154.5; 158.8 ug/ml
N/A N=267 Investigation of the Simplify® Cervical Artificial Disc
Cervical Degenerative Disc Disease
Primary: Number of Participants With Composite Clinical Success (CCS) of Simplify Disc — 68; 132 Participants — p=<.001
N/A N=48 Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial
Neck Pain · Pain in Arm, Unspecified
Primary: Range of Traction Forces — 13.82; 38.3; 65.08; 17.19 Newtons (N)
N/A N=89 SECURE®-C Cervical Artificial Disc Clinical Study/ SECURE-C Cervical Artificial Disc Postmarket Approval Study
Symptomatic Cervical Disc Disease
Primary: Individual Patient Overall Success — 127; 81; 67 participants
Phase 4 N=140 Intubation of Patients With an Unstable Cervical Spine Using the CMAC Device
Laminectomy
Primary: Intubation Time (Seconds) — 35; 59 Seconds
Phase 2 N=74 Transforaminal Versus Lateralized Interlaminar Cervical Epidurals
Cervicogenic Upper Extremity Radiculopathy
Primary: Change in Pain Numerical Rating Scale (Averaged Over Past 24 Hours) — -3.38; -2.30 score on a scale — p=0.057
Phase 4 N=20 BIO4 Clinical Case Study: Cervical Spine
Degenerative Disc Disease · Trauma (Including Fractures) · Spondylolisthesis
Primary: Radiological Assessment : Fusion Status — 20 participants
Phase 3 N=416 PCM Cervical Disc System
Radiculopathy · Myelopathy
Primary: Individual Patient Overall Success — 142; 98 participants
N/A N=74 Dysphagia Following Anterior Cervical Spine Surgery; Steroid vs Saline
Dysphagia
Primary: Swallowing Difficulty — 16; 14; 5; 7 Participants — p=0.036