30 closest matches · ranked by relevance
Attention Deficit Hyperactivity Disorder
Primary: Change From Baseline in Total Score of Barratt Impulsiveness Questionnaire v.11 (BIS-11) After Single Dose (at Day 1) — -0.8; -0.4 Score on a scale
Impulsivity · Compulsive Overeating · Obesity
Primary: Change in NIH Examiner Flanker Task Reaction Time — -0.03; -0.12 seconds
Schizophrenia With Impulsivity
Primary: Change From Baseline Brain Activation in the Ventrolateral Prefrontal Cortex (VLPFC) Based on Change From Baseline to Week 6 in fMRI Blood Oxygen-level Dependent (BOLD)…
Impulsive Behavior
Primary: Stop Signal Task (SST) — 255; 215; 297 milliseconds
Impulse Control Disorder · Parkinson Disease
Primary: Percentage of Participants Assessed as Very Much Improved or Much Improved Based on the Clinical Global Impression-Improvement (CGI-I) Scale — 54.4; 33.1 percentage of…
Mild Traumatic Brain Injury
Primary: Blood Oxygen Level Dependent (BOLD) Brain Signal Measured Using Functional MRI. — 270; 111 voxels — p=<0.0001
Attention Deficit Hyperactivity Disorder
Primary: Area Under the Receiver Operating Characteristic (ROC) Curve- Groundskeeper Game — 0.78 Proportion of accurate ADHD Diagnoses
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: Efficacy and Safety of SPN-810 on the Frequency of Impulsive Aggression (IA) Measured by the Impulsive Aggression Diary — -48.16; -47.88; -58.56 percent change of IA…
Attention Deficit Hyperactivity Disorder
Primary: Number of Participants That Tested High (6 or More Symptoms) for ADHD by Type Determined by Adult ADHD DSM IV-TR Checklist — 2; 5; 2 Participants
Cocaine Dependence
Primary: Immediate Memory Task
Attention Deficit Hyperactivity Disorder
Primary: Attention Deficit / Hyperactivity Disorder Total Sum Score of All 18 ADHD Symptom Items — 26.54; 25; 18.94; 18.46 Score
Obesity
Primary: Percent Weight Change — 23.0; 26.2; 23.3 percent weight change
Alcohol Dependence
Primary: Total Number of Drinks Per Day During Natural (Usual Environment) Conditions — 5.8; 6.4 standard drinks
Attention Deficit Hyperactivity Disorder (ADHD)
Primary: Efficacy and Safety of SPN-810 on the Frequency of Impulsive Aggression (IA) Measured by the Impulsive Aggression Diary — -54.12; -51.64 Percent Change of IA behaviors…
Opioid-use Disorder · Tobacco Use Disorder
Primary: Attentional Bias for Smoking Stimuli — 501.53; 406.70 milliseconds
Tourette Syndrome
Primary: Stop Signal Reaction Time (SSRT) — 249; 245 milliseconds — p=0.49
Traumatic Brain Injury · Suicidality
Primary: Iowa Gambling Test — -4.2; 1.7; 3.5; 5.3 Total Raw on a scale from -100 to 100 — p=>.05
Major Depressive Disorder · Irritability
Primary: Change From Baseline to Week 6 in SIS Total Score — -21.13 units on a scale
Alcohol Abuse · Cognitive Deficit in Attention
Primary: Participant Retention — 85.71; 88.89 percentage of participants
Antisocial Behavior · Aggression
Primary: Change in Antisocial Behavior Inclinations at 24 Hours — 1.41; 3.05 score on a scale
Alcohol Use Disorder
Primary: Delay Discounting (DD) Rates — -4.69; -5.15; -4.92; -5.58 ln(K-value) — p=.60
Cocaine Dependence
Primary: Change in Interaction of the Serotonin Receptor (5-HTR) Type-2C Cys23Ser Single Nucleotide Polymorphism (SNP) and a 5-HT2AR Antagonist on the Functional Circuitry…
Smoking
Primary: Signal Change in Functional Magnetic Resonance Imaging (fMRI) BOLD Signal Between Response Inhibition Trials and Control Trials in Right Inferior Frontal Cortex (rIFC)…
Mood Disorder · Disruptive Behavior Disorders
Primary: Change in Affective Reactivity Index - Youth (ARI-Y) — -2.9; -0.8 score on a scale
Tobacco Cessation
Primary: Number of Participants With 7-day Point Prevalence Abstinence From Smoking at Week 4 — 12; 13; 9; 18 Participants
Antisocial Behavior · Aggression
Primary: Number of Pins Inserted Into a Virtual Voodoo Doll After 48 Hours — 3.77; .64 pins
Bipolar II Disorder
Primary: Change in Subjective Effects as Assessed by Score on "Feel Drug", "Feel High", "Like Drug", and "Want More" Sub-scales of Drug Effects Questionnaire (DEQ). — 18.88…
Cocaine Use Disorders · HIV
Primary: Working Memory Assessed by Domain Deficit Score — .29; .21; .14; .26 Score on a scale — p=0.039
Obsessive-Compulsive Disorder
Primary: Change in Response Time on Stop Trials of the Stop Signal Task — -26.2; -31.7 milliseconds
Hoarding Disorder
Primary: Number of Patients Who Met and Exceeded Response Criteria of Attention Deficit Hyperactivity Disorder Symptom Scale — 4 participants