N/A N=78 Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) (CASL)
Alzheimer Disease · Dementia
Primary: FCI Score at Follow-up — 147.3; 164.0; 123.3; 150.8 points awarded for correct items
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=146 Cognitive Training and Practice Effects in Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Auditory Memory Attention Index — 89.0; 94.3 standard score units — p=<0.01
N/A N=58 Project IMPACT: Improving Memory Performance by Applying Cognitive Training
Cocaine Use Disorders · HIV
Primary: Working Memory Assessed by Domain Deficit Score — .29; .21; .14; .26 Score on a scale — p=0.039
Phase 1 N=52 Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment · Alzheimer's Disease · Traumatic Brain Injury
Primary: Memory Test Accuracy on Trained Stimuli — 53.9; 37.6; 48.9; 37.3 Percent correct
N/A N=107 Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Alzheimer's Disease
Primary: Face-name Memory Test Performance — -.28; -.01; -1.29; -1.76 pairs correctly recalled/recognized
N/A N=156 A Mobile Informatics Solution to Aid in Memory
Alzheimer Disease · Dementia
Primary: PWMC Loneliness — 4.90; 5.28 units on a scale
N/A N=107 Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Memory Disorders · Memory Impairment
Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score
Phase 2 N=96 Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment (MCI)
Primary: Brain Activity in the Dentate Gyrus / CA3 Subregion of the Hippocampus Measured With Blood Oxygenation Level Dependent (BOLD) Functional MRI — -0.1203; 0.4353; -0.2238…
N/A N=68 Everyday Memory Intervention
Aging
Primary: Everyday Memory Failures — 0.55; 0.62 average daily number memory failures/day — p=.67
N/A N=81 Memory and Fear Study (Fear of Memory Loss Study)
Anxiety and Fear
Primary: Fear and Avoidance of Memory Loss (FAM) Scale Score at Follow-up — 63.9; 60.3 score on a scale
Early Phase 1 N=35 Remediation of Impaired Self-Regulation in Patients With Mild TBI
Mild Traumatic Brain Injury
Primary: Blood Oxygen Level Dependent (BOLD) Brain Signal Measured Using Functional MRI. — 270; 111 voxels — p=<0.0001
N/A N=59 Mnemonic Strategy Versus Spaced Retrieval Training in Those With Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Percent of Correct Object Location Associations Assessed up to 1 Month Post-treatment — 80.0; 62.45 percent correct — p=<.001
N/A N=50 Wayfinding Intervention in High-Fidelity Long-Term Memory
Long-Term Memory Decline · Mild Cognitive Impairment
Primary: MDT Change in Mnemonic Discrimination — 0.09; 0.01 LDI score on a scale — p== 0.016
N/A N=104 Improvisational Movement for People With Memory Loss and Their Caregivers
Alzheimer's Disease (Incl Subtypes) · Dementia · Mild Cognitive Impairment
Primary: Quality of Life in Alzheimer's Disease (QOL-AD)--Participants With Dementia (PWD) — 35.42; 38.10; 35.56; 36.12 score on a scale
Phase 2 N=80 Metformin in Amnestic Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Change in Total Recall Score in the Selective Reminding Test — 5.7; 9.4 score on a scale — p=0.05
Phase 2 N=31 Memory and Insulin in Early Alzheimer's Disease
Alzheimer's Disease
Primary: fMRI Measure of Hippocampal Activation — 36.4; 41.3 percentage of active voxels
N/A N=10 Transcranial Direct Current Stimulation (tDCS)
Brain Fog
Primary: Perceived Ease of Use After 4 Weeks of Daily tDCS Use (TAM Score) — 30.5 units on a scale
Phase 4 N=83 Lithium As a Treatment to Prevent Impairment of Cognition in Elders
Mild Cognitive Impairment
Primary: California Verbal Learning Test II — 6.9; 6.2; 6.46; 5.10 units on a scale — p=0.048
N/A N=21 Improving Memory Performance by Applying Cognitive Training
HIV
Primary: Change in Working Memory — 51.33; 43.15 mean T score on working memory tests — p=.013
Phase 2 N=113 Nutraceutical Effects on Long-Term Memory
Aging
Primary: Delay Eyeblink Conditioning — 52.32; 56.88 percentage of conditioned responses
N/A N=68 Mild Cognitive Impairment and Obstructive Sleep Apnea
Obstructive Sleep Apnea · Mild Cognitive Impairment
Primary: Hopkins Verbal Learning Test-Revised (HVLT-R) — 23.52; 20.04; 23.68; 20.39 score on a scale
Phase 4 N=61 Combination Treatment Study for Memory Impairment and Depression
Depression · Mild Cognitive Impairment
Primary: Selective Reminding Test (SRT) Total Recall — 45.6; 46.6 Words
Phase 4 N=28 Mild Cognitive Impairment in Parkinson's Disease
Parkinson's Disease · Mild Cognitive Impairment
Primary: Alzheimer's Disease Cooperative Study- Clinical Global Impression Change (ADCS-CGIC) — 3.92; 3.48 scores on the CGIC
N/A N=145 Cognitive Rehabilitation Therapy for Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Change in Objective Cognitive Performance Composite z Score — .24; .14 Z score
N/A N=12 Feasibility of the Memory and Attention Adaptation-Training Geriatrics Intervention in Older Cancer Survivors With Mild Cognitive Impairment
Cognitive Dysfunction
Primary: MAAT-G Feasibility Completion Rate — 10 Participants
N/A N=29 Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?
Epilepsy
Primary: The Change Scores in Memory Measures From Baseline to Post-treatment/Placebo Will be Compared Between the Memantine Treatment and Placebo Groups. — 1.00; 1.78; 4.38…
N/A N=101 Water-based Activity to Enhance Recall in Veterans
Mild Cognitive Impairment
Primary: Retention and Recruitment Rates — 21 Participants
N/A N=16 Improving Physical Activity With Cognitive Impairment
Mild Cognitive Impairment · Caregiver Burnout
Primary: TPAB Intervention Participant Retention — 5; 5; 3; 3 Participants
Phase 4 N=21 Phenytoin for Memory Impairment Secondary to Megestrol
Cognitive Impairment
Primary: Rey Auditory Verbal Learning Test (RAVLT) — 51.89; 45.90; 48.37 T-scores — p=0.003
N/A N=4 Imagine to Remember: Improving Medication Adherence in Pre- and Type 2 Diabetes
Medication Adherence
Primary: Medication Adherence — 34; 42 percent change — p=0.0002