N/A N=76 Neural Basis of Sensory and Motor Learning: Functional Connections
Basic Science
Primary: Resting-state PMv-M1 Functional Connectivity (Fisher Z-transformed Correlation) — 0.64 unitless (Fisher z-score)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=40 Learning in Stroke
Stroke · Sensorimotor Impairment
Primary: Learning Rate as Indexed by Change in the Precision of Visuomotor Grip Force Adjustment (i.e., Reduction of Precision Error in Force Adjustment) — -1.48; 0.303…
N/A N=64 Cortical Contributions to Motor Sequence Learning
Brain Injuries
Primary: Serial Reaction Time Task (SRTT) Performance — 31; 35; 38; 24 milliseconds (ms)
N/A N=38 Improving Locomotor Learning With Brain Stimulation
Motor Learning
Primary: Prefrontal Cortical Activity — 0.04; 0.11; 0.58; -0.62 μM
N/A N=24 Facilitating Implicit Learning to Improve Neurorehabilitation in Stroke
Cerebral Stroke
Primary: Quality of Motor Performance — .49; .67 percentage of samples not 'on' task
N/A N=15 Robotic Assessment of Lower Extremity Motor Learning
Healthy Subjects
Primary: Step Length Adaptation — 83.6 % of step length compensated for
Phase 2 N=14 NMDA Receptors in Motor Learning in Humans
Stroke
Primary: Grip Strength of Affected Hand — 3.95; 5.72; 4.90; 8.44 Newton
N/A N=30 Effect of Aging on Cortical Excitability and Motor Learning
Aging
Primary: Magnetic Resonance Spectroscopy — 0.41; -0.29 ppm — p=0.05
N/A N=87 Frontal and Parietal Contributions to Proprioception and Motor Skill Learning
Basic Science
Primary: Motor Skill — 66.6; 59.4; 59.9; 64.9 Accuracy (%) — p=0.55
N/A N=42 Effect of Levodopa on Postural Motor Learning in Parkinson Disease
Parkinson Disease
Primary: Change in Movement of Center of Mass (COM) After Postural Perturbation — 0.31; 0.28; 0.32; 0.26 meters
N/A N=25 Motor Control Physical Therapist Support Stroke
Stroke
Primary: Center of Pressure Path Length — 98.5; 156.1 cm^2
N/A N=56 The Effect of Acute Intermittent Hypoxia on Motor Learning
Incomplete Spinal Cord Injury
Primary: Change in Corticospinal Excitability — 0.528; 0.132 mV*percentage of RMT — p=0.0098
N/A N=40 Influence of Timing on Motor Learning
Cerebrovascular Accident
Primary: Motor and Strength Outcome Measure Using Box and Block Test — 2.3; 4.3 blocks
Phase 1 N=82 Effects of RLIC on Motor Learning in Middle-aged and Older Adults
Adults · Older Adults
Primary: Change in Balance Score — 5.55; 4.81 seconds — p=0.984
N/A N=57 Objective Assessment of Upper Extremity Functioning of Stroke Patients Before and After Rehabilitation
Stroke
Primary: Fugl-Meyer Assessment. — 38.32; NA; 47.6; NA units on a scale
N/A N=4 Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
Stroke
Primary: Arm Motor Abilities Test Functional Domain (AMAT - F) — .54 units on a scale
Phase 1 N=72 CONTROL Walking Study
Aging
Primary: Walking Speed Change From Baseline — 0.033; 0.041 meters per second
N/A N=10 Modulating Interaction of Motor Learning Networks in Rehabilitation of Stroke
Stroke · Stroke, Chronic · Stroke, Middle Cerebral Artery With Infarction
Primary: Change From Baseline in Sequential Response Time to Post-Intervention — 8.68; 8.84; 8.32; 7.96 seconds
N/A N=10 Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke
Stroke
Primary: Change From Baseline in Fugl-Meyer Assessment (FMA) - Upper Extremity Subtest — 11.0; 2.0; 8.5 score on a scale
Phase 1 N=34 Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults
Healthy, Young Adults
Primary: One-repetition Maximum of Wrist Extensors — 22.6; 23.7; 32.0; 29.9 lbs — p=0.002
N/A N=33 Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
Stroke
Primary: Aim 1: Mean Parameter Estimate for Maximal Motor Evoked Potential (MEPmax) Derived From Stimulus Response Curves (SRC) — 1.01; 1.63; 1.29; .73 mV
N/A N=54 Implicit Learning in Stroke Study
Stroke
Primary: Change in Modified Rivermead Mobility Index Score — 30.2; 34.4 score on a scale
Phase 2 N=36 Locomotor Training in Persons With Multiple Sclerosis
Multiple Sclerosis
Primary: Walking Speed as Assessed by 25' Timed Walk — 22.7; 10.6; 23.9; 9.8 seconds
Phase 1 N=40 Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement
Healthy, Young Adults
Primary: Balance Score — 9.9; 11.5; 7.0; 11.3 seconds — p=0.172
N/A N=87 Motor Training in PD
Parkinson Disease
Primary: Percent Signal Change — 0; 23; 35 percentage of baseline BOLD signal
N/A N=27 Cortical and Biomechanical Dynamics of Ankle Robotics Training in Stroke
Cerebral Stroke
Primary: Motor Control — 413.22; 523.94 1/s^2
N/A N=36 Locomotor Training (Walking Therapy) Post Stroke
Stroke
Primary: The Primary Outcome Measure Was Pre-treatment to Post-treatment Change in Self-selected Walking Speed. — 0.21 meters per second
N/A N=65 A Pilot Trial of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) to Enhance Motor Learning in Progressive Multiple Sclerosis (MS)
Multiple Sclerosis
Primary: Mean Preload Phase Duration (PLD) — 0.152; 0.238; 0.163; 0.202 seconds
N/A N=55 Incline Training to Personalize Motor Control Interventions After Stroke
CVA (Cerebrovascular Accident)
Primary: Change in Gait Speed — 0.15; 0.075; 0.127 meters/second
N/A N=49 Understanding Different Parameters in Locomotor Training (a Type of Walking Training) for Person After a Stroke
Stroke
Primary: Diagnostic — 1.57; 1.57; 1.55; 1.56 Z-score — p=0.981