N/A N=150 Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Anesthesia
Primary: Time for Preoxygenationfrom Face Mask Positioning to FEO2=90% — 190; 153; 140 seconds
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N/A N=40 Pre-Oxygenation Techniques in Pregnancy
Preoxygenation
Primary: End Tidal Oxygen Concentration (ETO2) Following Tidal Volume Breathing Using Either Face Mask or OptiFlow — 91.0; 87.4 Percentage units of end-tidal oxygen
N/A N=37 Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation
Hypoxia
Primary: End-tidal Oxygen — 78.1; 78.6 End tidal oxygen saturation percentage
N/A N=26 Four Methods of Pre-oxygenation
Respiratory Failure
Primary: Exhaled Oxygen Concentration — 72; 86; 54; 77 % FeO2
N/A N=1,301 Pragmatic Trial Examining Oxygenation Prior to Intubation
Acute Respiratory Failure
Primary: Incidence of Hypoxemia — 57; 118 Participants
N/A N=91 Preoxygenation Using THRIVE Versus Facemask in Parturients
Preoxygenation
Primary: Preoxygenation Duration — 3.6; NA; NA minutes
N/A N=34 Preoxygenation With Optiflow™ - the Effect of Speech on Lung Oxygenation.
Unrecognized Condition
Primary: End Tidal Oxygen Fraction — 43.9; 81.9 percentage of End-Tidal Oxygen Fraction
N/A N=50 EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
Obesity, Morbid
Primary: Non Hypoxic Apnea Time — 216.7; 258.2 seconds — p=0.005
N/A N=20 EPO2-PV: Evaluation of Pre-Oxygenation Conditions in Morbidly Obese Volunteer: Effect of Position and Ventilation Mode
Morbid Obesity · Bariatric Surgery Candidate
Primary: Functional Residual Capacity — 2573; 2145; 2456; 2219 ml
Phase 3 N=100 Does High Intraoperative Inspired Oxygen Reduce Postoperative Arterial Oxygen Saturation?
Atelectasis
Primary: Oxygen Requirement to Maintain SpO2>90% — 1; 1; 1; 1 liters per minute
N/A N=360 Apneic Oxygenation During Airway Management in Pediatric Patients
Hypoxia
Primary: Time to First Event: Pulse Oximetry at 95%, or Successful Intubation — 106; 169 seconds
Phase 4 N=105 Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
Rapid Sequence Intubation
Primary: Real Time and Single Breath End-tidal (EtO2) Measurements — 34; 63; 92; 58.5 percentage of end-tidal oxygen
N/A N=482 The Use of Apneic Oxygenation During Prolonged Intubation in Pediatric Patients: a Randomized Clinical Trial
Intubation of Pediatric Dental Surgery Patients
Primary: Time of Oxygen Saturation Change — 30; 67; 75 seconds
Phase 3 N=201 Risk of Oxygen During Cardiac Surgery Trial
Cardiac Surgery
Primary: Intraoperative Systemic Oxidative Damage — 69; 83 pg/ml
N/A N=150 Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study
Respiratory Failure
Primary: Successful First Attempt at Endotracheal Intubation (Defined by Confirmed Placement of an Endotracheal Tube in the Trachea During First Laryngoscopy Attempt) After…
N/A N=35 Oxygenation Via Frova Bougie and Ambu Bag
Failed or Difficult Intubation
Primary: Tidal Volume (ml) — 954.8; 554.4; 893.5; 542.9 tidal volume (ml)
N/A N=72 Positive Pressure at Induction of Anesthesia in Children
Continuous Positive Airway Pressure · Hypoxia · General Anesthesia
Primary: Time Between Onset of Apnea and the Drop in 95% Oxyhemoglobin Saturation Levels — 227.65; 133.68 seconds — p=<0.0001
N/A N=206 EmergeNcy Department Apneic Oxygenation Versus Usual Care During Rapid Sequence Intubation
Diffuse Apneic Oxygenation
Primary: Mean (Average) Arterial Oxygen Saturation — 92; 93 Percent Saturation (SpO2)
N/A N=500 The Performance of Two Oxygen Delivery Devices Used After General Anesthesia.
Hypoxemia
Primary: Number of Participants With Hypoxemia in Both Groups — 0; 0 number of participants
N/A N=70 Supplemental Oxygen Study
Cesarean Section · Supplemental Oxygen · Umbilical Cord Gases
Primary: Umbilical Cord pH Levels — 7.29; 7.28 pH
N/A N=50 The Effect of Prolonged Inspiratory Time on Pulmonary Mechanics in Obese Patients
Hypoxia
Primary: PaO2(Partial Pressure of Oxygen in Arterial Blood) — 178.71; 198.04; 185.25; 202.54 mmHg
N/A N=5,749 Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project
30% Oxygen Concentration During Colorectal Surgery · 80% Oxygen Concentration During Colorectal Surgery
Primary: Number of Participants With One or More Composite Complications — 314; 314 Participants — p=0.85
N/A N=22 Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
Hypercapnia
Primary: Recovery From Anesthesia — 53.0; 62.9 minutes — p=>0.05
N/A N=56 High Flow vs Conventional Oxygen in Head and Neck Surgery
Pulmonary Disease
Primary: Proportion of Patients With Post-operative Pulmonary Complication — 2; 11 Participants
Phase 1 N=16 Reoxygenation After Cardiac Arrest II (REOX II Study)
Cardiac Arrest
Primary: Plasma Isofurans (pg/mL)/Isoprostanes (pg/mL) Ratio
N/A N=49 Prevention of Opioid-Induced Hypoxemia
Non-cardiac Surgery
Primary: Time-weighted Average of SpO2 Below a Threshold of 90% — 0.29; 0.11; 0.16; 0.10 % of SpO2 — p=0.120
N/A N=63 High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
Desaturation of Blood · Obesity · Colonoscopy
Primary: The Number of Desaturation Episodes — 0; 0 Episodes
N/A N=14 Comparison of Pharyngeal Oxygen Delivery by Different Oxygen Masks
Hypoxemia · Trauma · Acute Myocardial Infarction
Primary: Oxygen Concentration Measured at the Lips by Datex-Ohmeda Differential Paramagnetic Sensor — 66.6; 97.1; 81.2; 81.2 percentage of oxygen
N/A N=50 Pre-op Use of Incentive Spirometry in Obese Patients
Lung Function · Bariatric Surgery
Primary: Post Operative Incentive Spirometry Volume — 1557.9; 1458.33 cc
N/A N=51 Impact of Prophylactic High Flow Nasal Oxygen in Post-Operative Thoracic Surgical Patients
Post-operative Pulmonary Complications
Primary: Number of Participants With Post-operative Pulmonary Complications — 1; 2 Participants — p=0.680