N/A N=31 Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
Smoking
Primary: Breath Sample (Expired Carbon Monoxide) — 18.77; 31.07; 25.38; 30.49 parts per million — p=0.92
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=85 Assessing Toxicity of Waterpipe Tobacco Smoking
Waterpipe Smoking
Primary: Comparing Cotinine Pre-to-post Change Between 2 Waterpipe Smoking Sessions: Heating Waterpipe Tobacco by (a) Charcoal vs (b) an Electric Head — 34.9; 26.4 ng/mL — p=0.115
N/A N=484 Parent eReferral to Tobacco Quitline
Secondhand Smoke
Primary: Number of Parent Smokers Who Enrolled in Quitline — 209; 245; 24; 5 Participants
N/A N=330 PRIDE: Preventing Respiratory Illnesses During Childhood Study
Tobacco Smoke Pollution
Primary: Air Nicotine Levels — 1.17; 0.58; 0.71; 0.51 mg/m^3
N/A N=1,132 Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes
Tobacco Use, Cigarette Use
Primary: Very Low Nicotine Content (VLNC) Misperception — 3.12; 3.04; 3.04; 3.36 score on a scale
N/A N=359 Novel Determinants and Measures of Smokeless Tobacco Use: Study 1
Smokeless Tobacco Use · Tobacco Dependence
Primary: Extent of Toxicity: Mean of Median Values of NNK+NNN in 7 Smokeless Tobacco Brands — 2.4; 2.25; 3.19; 5.51 ug/g
N/A N=120 Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)
COPD, Chronic Obstructive Pulmonary Disease
Primary: Change in Quality of Life -St. George's Respiratory Questionnaire (SGRQ) — -2.9; 1.5 score on a scale — p=0.025
N/A N=37 Cigarette Smoking Decision Study
Tobacco Smoking
Primary: Demand Intensity as Assessed by a Behavioral Economic Demand Curve — 4.709677419; 2.580645161 puff bouts
N/A N=60 Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
COPD · Asthma · Second Hand Tobacco Smoke
Primary: Respiratory Rate — 21.66; 21.57 BR/M breathing rate per min
N/A N=36 Palatability of Experimental Cigarettes - Study 2
Smoking
Primary: Change in UrineTotal Nicotine Equivalent (TNE) Between Baseline and Week 1 — -16.2; -7.6; 1.3 nmols/ml
N/A N=2,924 Smoke-free Air Coalitions in Georgia and Armenia
Smoking
Primary: Secondhand Smoke Exposure — 11.70; 12.08; 10.86; 10.51 days with SHS exposure
N/A N=40 Acute Effects of Cigarette Packaging and Charcoal Filtration on Perceptions, Use Behaviors, and Harm Exposure
Smoking Behaviors
Primary: Number of Puffs Taken (Video-scored Smoking Behavior Outcome 1) — 15.8; 16.7; 19.1; 19.6 puffs
Phase 3 N=81 Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
Tobacco Dependence
Primary: Tobacco Abstinence at 12 Weeks — 8; 5 participants
Phase 4 N=90 Tobacco Use Treatment in Cancer Patients
Smoking, Cigarette
Primary: Smoking 7-Day Point Prevalence at 12 Weeks — 2; 2; 3 Participants
N/A N=452 Smoke-free Home Intervention in Permanent Supportive Housing
Smoking Cessation · Second Hand Tobacco Smoke
Primary: Proportion of Resident-participants Who Adopt a Smoke-free Home Voluntarily — 0.068; 0.048 proportion of resident-participants
Phase 2 N=130 Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
Nicotine Dependence
Primary: Toxicant Exposure by Products — 835.3; 782.1; 726.8; 0.157 ng/ml — p=0.002
N/A N=33 Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors
Cardiometabolic Health
Primary: Systolic Blood Pressure — 127.0; 126.5 mm Hg — p=0.588
N/A N=396 Babies Living Safe and Smokefree
Second Hand Tobacco Smoke · Nicotine Dependence
Primary: Child Urine Cotinine — 1.00; .97; 1.09; 1.00 log transformed ng/mL
N/A N=18 Tobacco Cessation in Public Housing
Smoking Cessation · Smoking Reduction · Smoking, Tobacco
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Nicotine Dependence (Short Form 8a) Score — 11.2 score on a scale
Phase 2 N=775 Project 1, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Childbearing Age Women
Tobacco Use Disorder
Primary: Cigarettes Per Day (CPD) — 25.28; 19.95; 17.74 cigarettes per day — p=<0.0001
Phase 4 N=32 Nicotine Patch as an Adjunctive Intervention to Reduce Secondhand Smoke Among NICU Families
Environmental Tobacco Smoke · Smoking Cessation
Primary: Feasibility as Assessed by Number of Participants Who Accepted NRT Patches From Research Staff. — 13 Participants
N/A N=64 Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
Tobacco Use
Primary: Number of Cigarettes Purchased — 154.7; 119.2 average number of cigarettes
Phase 2 N=49 Impact of Nicotine Reduction on Adolescent Cigarette Use, Alternative Tobacco Use, and Harm From Tobacco
Nicotine Dependence, Cigarettes, Uncomplicated
Primary: Average Cigarettes Smoked Per Day — 4.3; 8.0 average cigarettes per day — p=.111
N/A N=143 Wood Smoke Interventions in Native American Populations
Respiratory; Disorder, Functional, Impaired · Respiratory Infection Other
Primary: Post-intervention FEV1 — 1.9; 2.1; 2.0 liters — p=0.10
N/A N=326 Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age
Tobacco Use Disorder
Primary: Number of Cigarettes Smoked Per Day — 22.54; 14.32; 11.76; 7.63 cigarettes per day
N/A N=165 NICU Asthma Education and Secondhand Smoke Reduction Study
Respiratory Illness
Primary: Infants Living in Smoke-free Environments. — 65; 64 participants
N/A N=136 COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM
Substance-Related Disorders
Primary: High Ventilated Cigarette Purchases — 104.22; 29.64; 52.38; 47.41 single unit quantity purchased
N/A N=231 A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products.
Tobacco Use
Primary: Summary of Urine Total NNAL Amount Excreted and Absolute Change From Baseline (ng/24 Hour) by Study Group and Study Day (mITT Population) — 511.889; 581.676; 548.751…
N/A N=104 Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Tobacco Use Disorder
Primary: Product Preference — 27; 23; 24; 24 participants
N/A N=6,011 European Regulatory Science on Tobacco: Policy Implementation to Reduce Lung Diseases (EUREST-PLUS)
Tobacco Dependence
Primary: Number of Participants Who Think About the Harm of Smoking — 67; 272; 192; 194 Participants