Phase 3 N=8 Vaping THC From Electronic Cigarettes
Marijuana Dependence
Primary: Mean Delivered and Retained Doses — 0.016; 0.018; 0.026 grams (g)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=31 JUUL vs. Mod E-cigarette Study
Smoking · Tobacco Use
Primary: Choices to Smoke — 26.15; 30; 38.33 Percentage of Total Choices
N/A N=29 Electronic Cigarette Use in Young Adult Men and Women
Cigarette Smoking · Tobacco Use
Primary: Contextual Factors Associated With Tobacco Use Episode Reported Via Ecological Momentary Assessment — 3; 22; 11; 12 tobacco use episodes — p=0.002
N/A N=88 Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth
E-cigarette Use
Primary: Plasma Nicotine Concentration — 0.78; 1.08; 0.89; 1.16 ng/ml
N/A N=71 Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping
E-cigarette Use · Vaping
Primary: Participant Recruitment and Retention — 37; 31 Participants
N/A N=40 The Acute Effect of Vaping on Food Intake
Energy Intake · Food Intake · E-Cig Use
Primary: Energy Intake — 1102.1; 1003.4; 910.4; 868.3 Kilocalories
N/A N=1,369 Impact of E-cigarette Device Warnings
Vaping Behaviors
Primary: Mean Vaping Quit Intentions Score — 2.5; 2.5; 2.2 score on a scale — p=<.001
N/A N=33 Assessing Electronic Cigarette Nicotine Flux
Electronic Cigarette Use
Primary: Plasma Nicotine Concentration — 2.00; 1.92; 1.64; 1.62 mg/ml
N/A N=45 Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users
Electronic Cigarettes
Primary: Change in Plasma Nicotine — 8.68; 8.28; 9.53; 12.00 ng/ml
Phase 4 N=508 Research and Innovation to Stop E-cigarette/Vaping in Young Adults
Nicotine Dependence · E-Cig Use
Primary: 7-day Point Prevalence Vaping Abstinence — 55; 54; 61; 59 Participants — p=0.14
N/A N=37 Menthol Flavored E-cigarette Use During a Simulated Ban of Menthol Cigarettes
Tobacco Use Disorder
Primary: Number of Cigarettes Smoked Per Day — 2.2; 1.8; 6.0; 7.1 model estimated cigarettes per day
N/A N=61 A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Nicotine Dependence · Nicotine Addiction · Nicotine Use Disorder
Primary: Overall Treatment Satisfaction Rating — 3.8 units on a scale
N/A N=372 Examination of Low Wattage and High Wattage E-Cigarettes
Smoking, Cigarette · Smoking, Tobacco · Nicotine Dependence
Primary: Complete Change From Conventional Cigarettes - Self Report — 0; 12; 10; 0 Participants
N/A N=93 Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns
Smoking · Tobacco Use
Primary: Mean Cigarettes Per Day — 13.1; 12.6; 12.2; 13.3 cigarettes per day
Phase 4 N=261 Varenicline for Nicotine Vaping Cessation in Adolescents
Vaping · Nicotine Dependence
Primary: Continuous 4-week Nicotine Vaping Abstinence at End of Treatment (Weeks 9-12) — 45; 12; 5 Participants — p=<0.001
N/A N=350 Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures
Smoking, Cigarette
Primary: Proportion of Participants With Self-Reported 7-day Point Prevalence Abstinence From Cigarettes — 41; 33 Participants
N/A N=40 Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation
Behavior, Health Risk · Implementation Science · E Cigarette Use
Primary: Engagement_remote checkin_3 — 6; 5; 6; 5 Participants — p=0.820
N/A N=117 The Moment Study: Mixed Method E-cigarette Study
Smoking
Primary: Cigarette Use — -1.82 cigarettes
N/A N=362 Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
Vaping
Primary: Change in Percentage of Participants Susceptible to Future Vaping — 1.1; -5.7; -2.3; -3.2 percentage of participants
Early Phase 1 N=62 Responses to E-Cigarette Advertising
E-Cig Use
Primary: Attention to Specific ad Feature — -1.7062; -0.9676; -1.8238 Beats per minute
N/A N=52 Impact of E-cigarette Nicotine Concentration on Compensation
Smoking Cessation
Primary: Total Inhaled Volume — 416.5; 490.3 mL
N/A N=22 The Effect of Electronic Cigarette Liquid Characteristics in Smokers.
Electronic Cigarettes
Primary: Plasma Nicotine Concentration — 12.32; -0.22; 7.09; 5.85 ng/ml
N/A N=1,565 Impact of Vaping Prevention Advertisements
Vaping
Primary: Mean Susceptibility to Vaping Score — 2.16; 2.21; 2.36 score on a scale
N/A N=25 Effects of Cigarette and E-cigarette Flavors on Substitutability in the ETM
Cigarette Smoking Behavior
Primary: Nicotine/Tobacco Products Substitution — 1326.25; 206; 120.83; 46.79 mg of nicotine purchased
N/A N=44 Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)
Electronic Cigarette Use
Primary: Effort for Product Puffs With Cross Product Progressive Ratio Task (CP-PRT) — 6.30; 6.38; 6.34; 5.94 Breakpoint (highest trial completed)
N/A N=480 Impact of E-Cigarette Prevention Messages on Adolescents
Vaping Behavior
Primary: Mean Susceptibility to Vaping Score — 1.91; 1.82 score on a scale
Phase 1 N=16 The Interaction of Flavor With Nicotine Form in Adult Smokers
Nicotine Dependence
Primary: Changes in Liking of E-cigarette Overall — 14.2; 5.3; 11.9; 2.2 score on a scale — p=0.01
N/A N=71 Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers
Electronic Nicotine Delivery System Flavors
Primary: Average Daily Cigarette Use — 10.3; 17.3; 12.3; 5.3 number of cigarettes per day
N/A N=22 Assessment of Two New Electronic Cigarettes in Cigarette Smokers
Electronic Cigarettes
Primary: Change in Plasma Nicotine — 7.62; 10.65; 18.31; 7.19 ng/ml
N/A N=139 Cigarette Smoking Among Young Adults
Cigarette Smoking · Smoking Behaviors
Primary: Puff Topography — 1108; 1045.2; 1084.6 mL