N/A N=65 Ventilator-induced Lung Injury Vortex in Patients With SARS-CoV-2
ARDS · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Number of Participants Who Survived and Died — 1; 31; 14; 19 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,705 ED Lung Protective Ventilation to Reduce Complications
Mechanical Ventilation · Ventilator-associated Conditions · ARDS
Primary: Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department — 171; 38 participants
N/A N=219 Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Respiratory Failure · Mechanical Ventilation · Acute Lung Injury
Primary: To Further Characterize ED Mechanical Ventilation — 500 mL
Phase 2 N=33 Hemodynamics and Extravascular Lung Water in Acute Lung Injury
Acute Lung Injury
Primary: The Primary Efficacy Variable Will be the Total Reduction in Measured Lung Water
N/A N=320 Intensive Alveolar Recruitment Protocol After Cardiac Surgery
Ventilator Induced Lung Injury · Cardiac Disease · Acute Lung Injury
Primary: Severity of Pulmonary Complications in the Post-operative Period — 15; 26 percentage of participants — p=0.016
N/A N=566 Mode Of Ventilation During Critical IllnEss Pilot Trial
Respiratory Failure
Primary: Ventilator-free Days (VFDs) to Day 28 After Enrollment — 23; 22; 24 Ventilator-free days to day 28
N/A N=46 the Effect of Dopamine on Mechanical Ventilation Induced Lung Injury
Acute Lung Injury
Primary: Correlation Coefficient (r) Between Duration of Mechanical Ventilation and DRD1 Expression — -0.555 pearson Correlation Coefficient — p=<0.01
N/A N=12 Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury
Acute Respiratory Distress Syndrome · Acute Lung Injury
Primary: Oxygenation — 10 Participants
Phase 2 N=18 Early Insulin and Development of ARDS
Respiratory Distress Syndrome, Adult · Sepsis · Hyperglycemia
Primary: Plasma Levels of Free Fatty Acids, Tumor Necrosis Factor-α, Interleukin-6, and Von Willebrand Factor Antigen
N/A N=30 Comparison of Low and High Tidal Volumes in Acute Spinal Cord Injury
Spinal Cord Injuries
Primary: Number of Episodes of Pneumonia — .13; .4 episodes of pneumonia
N/A N=524 Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Primary: Ventilator-free Days (VFDs) — 18.4; 16.1 days
N/A N=50 VivaSight Double Lumen Tube for Single Lung Ventilation
Double Lumen Endotracheal Tube · Single Lung Ventilation
Primary: Number of Participants Requiring Flexible Fiberoptic Bronchoscopy — 25; 7 Participants
N/A N=32 Effort of Breathing Guided Ventilator Protocol
Ventilators, Mechanical · Work of Breathing
Primary: Percentage of Protocol Recommendations Which Are Accepted by the Clinical Provider — 76 percentage adherant
N/A N=248 Real-time Effort Driven VENTilator Management
Ventilation Therapy; Complications · Diaphragm Disease · Pediatric Respiratory Diseases
Primary: Median Duration of Weaning — 0.09; 1.04; 2.03; 2.10 days — p=.045
N/A N=49 Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung Collapse · One-Lung Ventilation · Thoracic Surgery
Primary: Quantification of Gas Volume Coming From Ambient Air Towards the Alveoli Space of the Non-ventilated Lung During OLV With the Use of DLT and BB. — 504; 630 milliliters…
N/A N=26 Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia
Episodic Hypoxemia in Mechanically Ventilated Preterm Infants
Primary: Percentage of Time Spent With Arterial Oxygen Saturation < 75% — 5; 4.4 % of time — p=0.44
N/A N=269 Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Weaning Failure · Complication of Respirator [Ventilator]
Primary: Mortality — 10; 14 participants — p=0.03
N/A N=16 Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome · ARDS
Primary: Mechanical Power — 1.87; -2.50 J/min — p=.002
N/A N=460 Sustained Aeration of Infant Lungs Trial
Preterm Birth · Extreme Prematurity
Primary: Combined Outcome of Death or Bronchopulmonary Dysplasia — 125; 137 Participants
N/A N=37 Impact of Using Mini-Bronchoalveolar Lavage as a Diagnostic Test for Ventilator-Associated Pneumonia
Ventilator-Associated Pneumonia
Primary: Change in Antibiotic Usage or Exposure — 11.87; 7.76 days — p=0.26
N/A N=824 Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study
ARDS · Critical Illness · Acute Respiratory Distress Syndrome
Primary: Fidelity to LPV — 43.3; 19.1; 83.9; 31.0 Percentage of time during first 72 hours
Phase 2 N=400 LIPS-A: Lung Injury Prevention Study With Aspirin
Acute Respiratory Distress Syndrome
Primary: Number of Participants Who Developed Acute Respiratory Distress Syndrome (ARDS) Within 7 Days — 20; 17 participants — p=0.53
N/A N=8,151 Third International Study on Mechanical Ventilation
Acute Respiratory Failure
Primary: All-cause Mortality — 2269 Participants
N/A N=16 Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
Acute Respiratory Failure · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Respiratory System Driving Pressure Measure by Servo Ventilator (DPrs-servo) — 12.3 centimeters of water
Phase 4 N=129 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Acute Cardiogenic Pulmonary Edema
Primary: Number of Patients Who Were Intubated — 5; 4; 10 participants
N/A N=120 RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
Respiratory Insufficiency
Primary: Venilator Associated Events (VAE) — 44; 40; 4; 2 Participants
Phase 2 N=31 Vitamin D in Ventilated ICU Patients
Respiratory Failure
Primary: Number of Participants With Plasma 25(OH)D Concentration >30ng/mL at Baseline — 2; 2; 1 participants
N/A N=33 Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
Respiration, Artificial · Critical Illness · Chronic Disease
Primary: Functional Assessment: Handgrip — 3.6; 1.3 kg
N/A N=103 The Effectiveness of AAD and IPV to Treat Hospitalized Infants (<2years) With Acute Viral Bronchiolitis.
Bronchiolitis
Primary: Length of Hospital Stay — 3.5; 3.6; 4.5 days
Phase 2 N=167 Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
Acute Lung Injury · Sepsis
Primary: Modified Change in Sequential Organ Failure Assessment (mSOFA) Score — -2.96; -3.20 score on a scale