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Home › Medications › amiloride

amiloride

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of amiloride

3 trials tracked of amiloride: 1 in phase 3 or 4.

3Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 1 Other / NA 1
  1. Phase 3 Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism Completed
  2. Phase 2 Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease Completed
  3. N/A Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene Completed

Showing the 3 most-cited and recently-updated of 3 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
Nephrology RCT
Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients Distal diuretics change kidney chemistry in people with chronic kidney disease
This randomized controlled trial in 26 individuals with chronic kidney disease found that distal diuretics decreased plasma glutamine and tr…
A small trial found that taking amiloride and hydrochlorothiazide lowered glutamine and changed how the body handles waste in people with ch…
May 1, 2026
Phase II RCT: Amiloride reduces arterial stiffness and blood pressure in adults with obesity and metabolic syndrome
Diabetes & Endocrinology RCT
Phase II RCT: Amiloride reduces arterial stiffness and blood pressure in adults with obesity and metabolic syndrome Low-dose amiloride reduced arterial stiffness and blood pressure in adults with obesity
A phase II, single-center RCT of 137 adults with overweight/obesity and metabolic syndrome features found 24 weeks of low-dose amiloride (5 …
Low-dose amiloride reduced arterial stiffness and blood pressure in adults with obesity, offering a potential new tool to improve heart heal…
Apr 8, 2026