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Rheumatology
Meta-analysis
Systematic review and meta-analysis links injury severity and infection to hyponatremia in acute spinal cord injury patients
Spinal injury patients face higher hyponatremia risk with certain factors
This systematic review and meta-analysis evaluated factors associated with hyponatremia in 2,355 patients with acute spinal cord injury. The…
A major review found that specific injury types and infections raise the chance of low sodium in spinal cord patients. Targeted monitoring i…
Frontiers
May 5, 2026
Nephrology
RCT
Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
Distal diuretics change kidney chemistry in people with chronic kidney disease
This randomized controlled trial in 26 individuals with chronic kidney disease found that distal diuretics decreased plasma glutamine and tr…
A small trial found that taking amiloride and hydrochlorothiazide lowered glutamine and changed how the body handles waste in people with ch…
May 1, 2026
Pediatrics
RCT
Normal saline preservation solution increases serum sodium and blood pressure versus half saline in critically ill pediatric patients
Study in critically ill children compares two IV fluid types for sodium and blood pressure effects
A double-blind RCT of 88 critically ill pediatric patients in a PICU compared normal saline (0.9% sodium chloride) to half saline (0.45% sod…
Normal saline raises sodium and blood pressure more than half saline in critically ill children, guiding safer fluid choices for recovery.
NEJM
Apr 6, 2026