Proof of concept study uses preSCRIPT framework to annotate prescriptions in UK Biobank
preSCRIPT framework identifies genetic links to drug response in UK Biobank
This proof of concept study utilized the preSCRIPT framework to filter and annotate raw prescription data from the UK Biobank, which include…
A proof of concept study in the UK Biobank used preSCRIPT to find genetic links to how people respond to common medications like warfarin an…
Triple Pill Therapy Lowers Recurrent Stroke Incidence in Patients With Prior Intracerebral Hemorrhage
Single pill with three blood pressure drugs cuts stroke risk after brain bleed
This multinational randomized controlled trial enrolled 1670 patients with a history of intracerebral hemorrhage and baseline systolic blood…
A single pill combining three low-dose blood pressure drugs reduced recurrent stroke risk by 39% in people who had a brain bleed.
Meta-analysis finds amlodipine–ARB combination improves hypertension control vs monotherapy
Combining amlodipine with an angiotensin receptor blocker may improve blood pressure control.
This systematic review and meta-analysis of six studies in primary hypertension found that amlodipine–ARB combination therapy had 2.25 times…
A combination of amlodipine and an angiotensin receptor blocker showed better blood pressure control than amlodipine alone in patients with …
Sacubitril/valsartan shows greater LVMI regression than some antihypertensives in hypertension with remodeling
New Drug Shrinks Heart Muscle Better Than Old Options
A network meta-analysis of 851 patients with essential hypertension and cardiovascular remodeling found sacubitril/valsartan achieved greate…
A new analysis shows one specific medicine shrinks thickened heart muscle better than older blood pressure treatments, offering hope for rev…