Review of topical phage therapy for wounds and burns notes dosing standardization gaps
Why Topical Phage Therapy Needs a New Plan
This review examines the use of topical phage therapy for wound and burn conditions. The authors synthesize that effective treatment of matu…
Topical phage therapy works best when doctors standardize doses and delivery methods to break through bacterial shields in tough wounds and …
Antibiotic therapy versus appendectomy showed no difference in one-year complication rates for adults with imaging-confirmed acute appendicitis.
Is taking antibiotics or surgery better for your appendix, and what does the data really show?
This meta-analysis of individual patient data from randomized controlled trials included 2,101 adults with imaging-confirmed acute appendici…
Choosing antibiotics over surgery for your appendix carries similar risks for most, but a specific stone makes complications much more likel…
Single Preoperative Antibiotic Dose vs Week-Long Postoperative Course for SSI Prevention in TE Breast Reconstruction
Is one antibiotic dose enough to prevent infection after breast reconstruction?
A multi-institutional RCT of 214 women undergoing immediate tissue expander breast reconstruction compared a single preoperative antibiotic …
A single antibiotic dose before breast reconstruction led to a 17% infection rate, compared to 11% with a week of pills, but the study didn'…
Meta-analysis finds no significant complication difference with early oral antibiotics for pediatric bone infections
Early oral antibiotics for childhood bone infections show similar safety to longer IV treatment
A systematic review and meta-analysis of 7,881 children with bone and joint infections found no significant difference in complications betw…
Switching children with bone infections to oral antibiotics early is as safe as longer IV treatment and may shorten hospital stays by up to …
Meta-analysis finds topical antibiotic prophylaxis does not reduce endophthalmitis after intravitreal injection
Study finds topical antibiotics do not prevent eye infections after injections
A systematic review and meta-analysis of over 3 million intravitreal injections found no significant difference in endophthalmitis incidence…
Topical antibiotic eye drops do not prevent serious eye infections after injections, according to a review of over 3 million procedures.
Rapid Diagnostics Align 65% of ICU Antibiotic Prescriptions with Pathogen Results
Why Are Doctors Hesitant to Trust Quick Test Results for Pneumonia?
In the INHALE RCT, 65% of ICU antibiotic prescriptions aligned with BioFire FilmArray Pneumonia Panel results. Positive pathogen results led…
When rapid pneumonia tests find no germs, doctors often ignore the result and keep prescribing antibiotics, risking longer hospital stays an…