Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis
Case report: Brain infection in autoimmune hepatitis patient
This case report describes the management of disseminated nocardiosis in a 55-year-old man with autoimmune hepatitis. The patient showed gra…
A man with autoimmune hepatitis developed a rare brain infection after immunosuppression. Doctors treated it successfully with targeted anti…
Belimumab plus standard therapy shows numerically greater reductions in IgA, IgM, and anti-dsDNA antibodies
Trial Shows Belimumab May Help Manage Lupus Nephritis Symptoms
This Phase 3 randomized controlled trial of 446 adults with active lupus nephritis found that intravenous belimumab plus standard therapy re…
A Phase 3 trial identifies specific markers that may help predict how patients with lupus nephritis respond to belimumab treatment.
Corticosteroid and cyclophosphamide exposure are associated with higher mortality in Middle Eastern and North African SLE
Specific Medications Linked to Survival Rates in Lupus Patients
This meta-analysis of 3,478 adult patients in the MENA region found an all-cause mortality rate of 9.9% (95% CI: 7.2%-14.0%). While corticos…
New data identifies how specific medications and health conditions impact long-term survival for patients with systemic lupus erythematosus.
Retrospective review of tocilizumab, rituximab, and azathioprine in chronic relapsing inflammatory optic neuropathy
New Clue Found in Stubborn Eye Inflammation
This retrospective analysis reviews tocilizumab, rituximab, and azathioprine use in 60 patients with chronic relapsing inflammatory optic ne…
Knowing a patient's blood marker status can guide doctors to the right therapy to stop recurring eye inflammation.
Systematic Review and Network Meta-Analysis Compares Enteral Nutrition and Medications in Pediatric Crohn's Disease
Exclusive nutrition therapy beats steroids for healing Crohn's in kids
This systematic review and network meta-analysis evaluates enteral nutrition versus immunomodulators and corticosteroids in 1,182 pediatric …
Exclusive nutrition therapy was far better than steroids at healing Crohn's disease in children, with fewer side effects and no serious risk…
Guselkumab showed improved clinical remission in refractory ulcerative colitis versus placebo
Guselkumab shows promise for ulcerative colitis in this early phase 3 trial
This phase 3 randomized trial evaluated guselkumab in adults with moderately to severely active ulcerative colitis who had inadequate respon…
Patients with ulcerative colitis who failed other treatments achieved remission in a new trial using subcutaneous guselkumab injections.