Meta-analysis shows reduced oral microbial Shannon diversity in Crohn's disease versus controls
Oral bacteria shifts could reveal Crohn's disease risk
This meta-analysis reviews data from multiple cohorts involving 1,136 IBD patients and 759 controls. The authors synthesize findings on oral…
A new study links distinct mouth bacteria changes to higher gut inflammation levels in Crohn's disease patients.
Enteral nutrition therapy associated with clinical remission in 60% of Chinese inflammatory bowel disease patients over 6 weeks
Enteral nutrition helps many IBD patients reach remission faster
This retrospective cohort study evaluated enteral nutrition therapy in 750 Chinese patients with Crohn's disease or ulcerative colitis. Appr…
Special liquid food formulas helped 60% of patients reach remission faster while improving nutrition and reducing inflammation in their bodi…
Three Biomarkers Show High Diagnostic Accuracy for Ulcerative Colitis in Cohort Study
Three biomarkers show promise for diagnosing ulcerative colitis
This cohort study evaluated ARHGEF3, S100A8, and RHOU as diagnostic biomarkers for ulcerative colitis. A nomogram achieved AUCs of 0.991 in …
A new study identifies three biomarkers that may help diagnose ulcerative colitis and distinguish it from Crohn's disease.
Systematic Review and Network Meta-Analysis Compares Enteral Nutrition and Medications in Pediatric Crohn's Disease
Exclusive nutrition therapy beats steroids for healing Crohn's in kids
This systematic review and network meta-analysis evaluates enteral nutrition versus immunomodulators and corticosteroids in 1,182 pediatric …
Exclusive nutrition therapy was far better than steroids at healing Crohn's disease in children, with fewer side effects and no serious risk…
FDA Approves Stelara (ustekinumab) for moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis.
The FDA approved a drug called Stelara to treat several inflammatory conditions in adults and children.
The FDA approved ustekinumab for adult and pediatric patients 6 years and older with moderate to severe plaque psoriasis and active psoriati…
FDA approved Stelara to treat moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis in adults an…
FDA Approves Stelara (ustekinumab) for moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis.
The FDA has approved a new drug called Stelara for several inflammatory conditions.
The FDA approved ustekinumab for adult and pediatric patients 6 years and older with moderate to severe plaque psoriasis and active psoriati…
The FDA has approved Stelara to treat moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis in a…
Narrative review discusses M cell manipulation limitations in inflammatory bowel disease models
Can we target gut cells without breaking the whole immune system?
This narrative review addresses challenges in selectively manipulating M cells within traditional animal models and two-dimensional culture …
Scientists are looking for ways to treat Crohn's disease and ulcerative colitis by focusing on specific cells in the gut lining. Current met…
Upadacitinib shows 94.1% remission at 26 weeks in Crohn's disease cohort
Study compares upadacitinib and other therapies for Crohn's disease remission
This retrospective cohort study of 218 individuals with Crohn's disease found a 94.1% clinical remission rate at 26 weeks for upadacitinib, …
Upadacitinib showed a 94.1% remission rate for Crohn's disease patients at 26 weeks, but this finding comes from a very small group of just …
Neutrophil SIRL-1/IL-8 Ratio as a Diagnostic Biomarker for Inflammatory Bowel Disease
New Blood Ratio Could Spot IBD Faster
This single-center cohort study measured neutrophil SIRL-1 and serum IL-8 in 90 IBD patients and healthy volunteers. The SIRL-1/IL-8 ratio s…
A new blood ratio measuring two immune signals could help doctors diagnose Crohn's and Ulcerative Colitis faster and more accurately.
Narrative review explores multimodal approaches for autoimmune diseases including rheumatoid arthritis and Crohn's
Scarring From the Inside: How Your Immune System Can Turn Against Your Own Organs
This narrative review examines the integration of immune modulation, epigenetic reprogramming, and mechanobiological interventions for autoi…
Your immune system can cause permanent scarring inside organs like lungs and joints, driving autoimmune diseases such as rheumatoid arthriti…
Cross-sectional data suggest IgG glycans discriminate inflammatory bowel disease from controls.
A Simple Blood Test May Spot Crohn's and Colitis Early
This cross-sectional study analyzed 1,367 plasma samples from individuals with Crohn's disease or ulcerative colitis, healthy controls, and …
A simple blood test reveals a sugar pattern that spots inflammatory bowel disease early and shows how the illness quietly ages the body.
Video capsule endoscopy in children shows diagnostic yield for Crohn's disease but requires endoscopic placement
Tiny Camera Spots Crohn's Damage That Scans Miss in Kids
A retrospective single-center study of 60 children undergoing 76 VCE examinations found VCE supported new Crohn's diagnosis in 46% of cases …
A tiny swallowed camera found gut inflammation missed by standard scans in children with Crohn's disease, changing treatment plans for more …