HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
Sys. Review
Berberine exhibits antimicrobial and anti-inflammatory effects for managing various oral mucosal and dental conditions
Berberine Shows Potential for Treating Various Oral Health Conditions
This systematic review synthesizes the pharmacological properties of berberine in treating oral diseases including periodontitis, caries, an…
A review of berberine suggests it may help manage oral diseases like periodontitis and dental caries through its anti-inflammatory and antio…
Frontiers
Jul 25, 2026
Neurology
Guideline
Berberine identified as potential Alzheimer's treatment targeting HMGCR in astrocyte-driven model
New research identifies a potential target for Alzheimer's disease
This guideline presents a computational analysis identifying an autolysosome-astrocyte-associated diagnostic model for Alzheimer's disease, …
Scientists identified a specific gene as a key driver of Alzheimer's and found that the compound berberine may help target it.
Frontiers
Jul 15, 2026
Cardiology
Sys. Review
Natural products like polyphenols and berberine modulate gut microbiota to target atherosclerosis pathways
Natural products may target gut health to impact heart disease
This narrative review explores how natural products, including polyphenols and berberine, influence the gut microbiota-metabolite-vascular a…
Certain natural compounds like berberine and polyphenols may help manage atherosclerosis by improving gut health and reducing inflammation.
Frontiers
Jun 26, 2026
Infectious Disease
Meta-analysis
Berberine reduces weight, lipids in schizophrenia with metabolic syndrome: meta-analysis
Berberine may improve weight and cholesterol in schizophrenia patients
This meta-analysis of 3 RCTs (233 patients) found that adjunctive berberine significantly reduced body weight, BMI, waist circumference, tot…
Adding berberine to treatment could help people with schizophrenia manage weight, waist size, and cholesterol levels.
Frontiers
Jun 25, 2026
Diabetes & Endocrinology
Meta-analysis
Probiotics, synbiotics, and berberine modestly lower fasting glucose and HbA1c in type 2 diabetes
Probiotics and Berberine Modestly Lower Blood Sugar in Type 2 Diabetes
This meta-analysis of over 2,000 participants found that probiotics, synbiotics, and berberine produced significant but modest reductions in…
Probiotics, synbiotics, and berberine may help lower blood sugar and HbA1c, but the effects are modest.
May 30, 2026
Infectious Disease
Sys. Review
Review discusses sequential eradication strategies using EGCG, baicalin, and other compounds for potential therapeutic applications
Sequential herbal strategy faces manufacturing hurdles before clinical use
This review synthesizes evidence regarding a sequential eradication strategy involving barrier disruption, metabolic resuscitation, and term…
A review suggests a multi-step herbal approach for disease control, but experts warn that turning these complex mixtures into safe, approved…
Frontiers
May 26, 2026
OB/GYN & Women's Health
Sys. Review
Review Proposes Gut Microbiota-Ferroptosis Axis in PCOS and Potential TCM Role
Review explores gut bacteria link to PCOS and potential role of Chinese herbal medicine
A systematic review proposes a theoretical perspective that gut microbiota dysbiosis may trigger ferroptosis in ovarian granulosa cells in P…
A scientific review explored how gut bacteria imbalances might contribute to PCOS by triggering a specific type of cell stress called ferrop…
Frontiers
Apr 3, 2026