Biologics reduce severe asthma exacerbation rates in meta-analysis of 6 RCTs and a case-series
Biologics Show Significant Reduction in Severe Asthma Exacerbation Rates
This meta-analysis of 6 RCTs and a self-controlled case-series evaluates the impact of biologics on severe asthma exacerbation rates. The an…
New analysis shows that biologics significantly reduce severe asthma flare-ups, especially for patients with specific markers like high eosi…
Ulcerative Colitis Trials Shift Toward Biologics and Small Molecules Since 2019
Biologics and Targeted Drugs Show Growth in Ulcerative Colitis Trials
This scoping review maps clinical trials in active ulcerative colitis and finds a rapid increase in trial numbers since 2019, with biologics…
Newer treatments like biologics and small-molecule drugs are becoming more common in clinical trials for active ulcerative colitis.
Traditional Chinese medicine may alleviate Crohn's disease symptoms through multi-target and multi-pathway mechanisms
Traditional Chinese Medicine May Help Manage Crohn's Disease Symptoms
This systematic review examines the role of Traditional Chinese medicine (TCM) in managing Crohn's disease. The authors suggest TCM may alle…
Traditional Chinese medicine may work alongside Western treatments to improve symptoms and reduce relapse risks for people living with Crohn…
Older age, higher BMI, and comorbidities are associated with lower clearance rates in psoriasis patients
Factors Like Age and BMI Impact Psoriasis Treatment Success
This meta-analysis of 13,902 patients evaluates predictors of clinical response to biologic therapies in psoriasis. The analysis identifies …
New data shows that age, body mass index, and other health factors can influence how well patients with psoriasis respond to biologic therap…
Tissue-resident memory T cells drive disease relapse after biologic and JAK inhibitor discontinuation in atopic dermatitis
Tissue Memory Cells Linked to Atopic Dermatitis Relapse
This narrative review examines the role of tissue-resident memory (TRM) cells in the pathogenesis and chronicity of atopic dermatitis. The a…
New research identifies how certain immune cells may cause atopic dermatitis to return after patients stop using common treatments like biol…
Narrative review explores microbiome-targeting therapies for inflammatory bowel disease patients
New microbial therapies for inflammatory bowel disease show promise
This narrative review examines the potential of targeting the microbial-metabolic axis for patients with inflammatory bowel disease. The aut…
A review explores how targeting the microbial-metabolic axis might help patients with inflammatory bowel disease using treatments like fecal…
Late-onset rheumatoid arthritis shows higher DAS28 scores and lower remission rates compared to young-onset disease in a meta-analysis
Meta-analysis compares treatment outcomes in older versus younger rheumatoid arthritis patients
This meta-analysis reviewed data from over 5000 patients with late-onset rheumatoid arthritis (LORA) and young-onset rheumatoid arthritis (Y…
A large review found older patients with rheumatoid arthritis had higher disease activity and lower remission rates on biologics compared to…
Review of cohort data finds AD linked to psoriasis risk and biologics associated with lower risk
Atopic Dermatitis Raises Psoriasis Risk, But Biologics Help
This narrative review synthesizes findings from a large cohort study.
A massive study shows that while eczema increases the chance of getting psoriasis, modern biologic drugs significantly protect against this …
Guselkumab showed improved clinical remission in refractory ulcerative colitis versus placebo
Guselkumab shows promise for ulcerative colitis in this early phase 3 trial
This phase 3 randomized trial evaluated guselkumab in adults with moderately to severely active ulcerative colitis who had inadequate respon…
Patients with ulcerative colitis who failed other treatments achieved remission in a new trial using subcutaneous guselkumab injections.
Strategies to screen and reduce adverse events in patients with asthma using systemic corticosteroids
Asthma Patients Are Still Getting Too Many Steroids — Here Is Why That Matters
This systematic review examined real-world practice strategies aimed at identifying and screening patients at risk of adverse events associa…
Asthma patients face serious, preventable harm from overused systemic steroids, yet safer biologics aren't reaching enough people who need t…