HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Pediatrics
Cohort
Autologous hematopoietic stem cell transplantation improves disease-free survival in pediatric extraocular retinoblastoma patients
Children With Eye Cancer Now Have a New Hope for Survival
This retrospective analysis included 12 children with extraocular retinoblastoma treated with autologous hematopoietic stem cell transplanta…
Children with advanced eye cancer can now achieve long-term survival using their own stem cells, especially if the disease has not reached t…
Frontiers
Apr 29, 2026
Oncology
Sys. Review
Case report details long-term survival in appendiceal signet-ring cell carcinoma with uterine involvement.
A rare cancer found in the uterus and ovaries may be treated with surgery and chemo for over five years.
This case report describes a 45-year-old woman with signet-ring cell carcinoma of the appendix involving the uterus and ovaries. The patient…
A rare cancer starting in the appendix showed up in the uterus and ovaries. Treatment with surgery and drugs helped a woman survive past fiv…
Frontiers
Apr 23, 2026
Oncology
Sys. Review
Case report and literature review on concurrent t-AML and LNTB treated with chemoimmunotherapy
Two Rare Diseases Strike After Lung Cancer Treatment
This case report and literature review describes the management of a 54-year-old male with locally advanced lung squamous cell carcinoma, th…
A lung cancer patient treated with chemo and immunotherapy developed two rare diseases simultaneously: a new blood cancer and tuberculosis.
Frontiers
Apr 16, 2026
Rheumatology
Cohort
Case report suggests grade 3 ICI-induced inflammatory arthritis may correlate with sustained response to tislelizumab in advanced head and neck carcinoma.
Could a painful joint flare actually signal that cancer treatment is working long-term?
This case report and literature review describes a single patient with advanced unknown primary carcinoma of the head and neck receiving mai…
A patient with advanced head and neck cancer stayed in complete remission for over a year after joint pain from treatment forced doctors to …
Frontiers
Apr 14, 2026
Oncology
RCT
Penpulimab plus chemotherapy significantly improved progression-free survival in recurrent or metastatic nasopharyngeal carcinoma.
New drug plus chemo delays cancer growth in advanced nasopharyngeal cases
This randomized, double-blind phase 3 trial evaluated penpulimab combined with cisplatin/carboplatin and gemcitabine versus placebo plus che…
Adding penpulimab to chemotherapy delays cancer growth by nearly three months in advanced nasopharyngeal cases, offering new hope for patien…
Apr 13, 2026
Allergy & Immunology
Sys. Review
Case report and review of primary cervical melanoma shows inconsistent response to PD-1/PD-L1 inhibitors
Rare cervical melanoma cases show mixed results with immunotherapy and surgery
A case report of two patients with primary malignant melanoma of the cervix and a review of nine reported cases treated with PD-1/PD-L1 inhi…
Surgery alone fails for rare cervical melanoma, as 80% of patients progress on immunotherapy without chemotherapy or radiation.
Frontiers
Apr 9, 2026
Pulmonology & Critical Care
RCT
Nivolumab with chemotherapy and bevacizumab shows improved 4-year survival in advanced nonsquamous NSCLC
Nivolumab combination shows long-term survival benefit in advanced lung cancer trial
A Phase III randomized controlled trial of 550 patients with advanced nonsquamous NSCLC found nivolumab with carboplatin, paclitaxel, and be…
Adding nivolumab to standard lung cancer treatment helped patients live longer, with 34.7% surviving four years compared to 22.1% on placebo…
Apr 4, 2026
Gastroenterology
Meta-analysis
Platinum-based intraperitoneal chemotherapy improves disease-free survival after curative CRC resection
Study reviews chemotherapy method for colorectal cancer after surgery
A meta-analysis of 1,264 adults receiving curative colorectal cancer resection found platinum-based prophylactic intraperitoneal chemotherap…
Giving chemotherapy directly into the abdomen after colorectal cancer surgery helped patients stay cancer-free longer without adding serious…
Apr 2, 2026
OB/GYN & Women's Health
Phase II
Phase II trial tests induction chemo with carboplatin, paclitaxel, lapatinib before transoral surgery in SCCHN
Can a gentler, three-part treatment plan reduce side effects for head and neck cancer?
A single-arm phase II trial enrolled 40 previously untreated patients with SCCHN amenable to transoral surgery. Treatment involved 6 weeks o…
A three-part treatment plan for head and neck cancer aims to reduce harsh side effects by tailoring care based on surgery results.
CT.gov
Mar 30, 2026