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Home › Medications › ceftriaxone

ceftriaxone

7 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of ceftriaxone

16 trials tracked of ceftriaxone: 10 in phase 3 or 4 and 4 with published results. The most-cited published study has 60 citations.

16Trials tracked
10Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 3 Phase 3 7 Phase 2 4 Phase 1 2
  1. Phase 3 A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea Completed · 60 cited
  2. Phase 3 Zoliflodacin in Uncomplicated Gonorrhoea Completed · 25 cited
  3. Phase 4 Antibiotic Prophylaxis for Transrectal Prostate Biopsy Completed · 21 cited
  4. Phase 4 Prophylactic Antibiotics in Admitted Cirrhotics Completed · 4 cited
  5. Phase 4 A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) Completed
  6. Phase 3 Efficacy and Safety of Ertapenem Sodium (MK-0826) Following Colorectal Surgery in Chinese Adults (MK-0826-056) Completed
Show 10 more trials
  1. Phase 3 A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Completed
  2. Phase 3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed
  3. Phase 3 Clinical Trial Ceftriaxone in Subjects With ALS Completed
  4. Phase 3 A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia Completed
  5. Phase 2 Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of Gonorrhea Completed
  6. Phase 2 The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Completed
  7. Phase 2 Antibiotic Instillation in Appendicitis Completed
  8. Phase 2 A Study Evaluating the Effect of Esomeprazole on SYN-004 Degradation of Ceftriaxone In Adults With an Ileostomy Completed
  9. Phase 1 Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial) Completed
  10. Phase 1 Experimental Human Infection With Neisseria Gonorrhoeae Completed

Showing the 16 most-cited and recently-updated of 16 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Immediate antituberculosis therapy did not reduce mortality in HIV-related sepsis overall
Infectious Disease RCT
Immediate antituberculosis therapy did not reduce mortality in HIV-related sepsis overall Immediate TB treatment helps only those with confirmed infection in HIV sepsis
This trial investigated whether starting antituberculosis treatment immediately or using high doses improved survival in adults with HIV-rel…
In HIV sepsis, starting TB drugs immediately did not lower death rates overall, but helped only patients later confirmed to have TB.
Jun 1, 2026
Case report on Brucella periprosthetic joint infection after knee replacement
Orthopedics & Sports Medicine Sys. Review
Case report on Brucella periprosthetic joint infection after knee replacement Two rare knee infections treated with specific antibiotics and surgery
This is a case report of two patients with Brucella-induced periprosthetic joint infection after total knee arthroplasty. The authors descri…
Two patients with rare Brucella knee infections saw normal markers and restored motion after targeted antibiotic therapy and surgery.
Frontiers May 22, 2026
Meta-analysis links ceftriaxone to higher 30-day mortality in MSSA bloodstream infections
Infectious Disease Meta-analysis
Meta-analysis links ceftriaxone to higher 30-day mortality in MSSA bloodstream infections Ceftriaxone May Increase Death Risk In Bloodstream Infections
This meta-analysis of observational studies (2568 patients) found that ceftriaxone was associated with increased 30-day all-cause mortality …
Doctors should stop using ceftriaxone for bloodstream infections because it may raise the risk of dying within the first month of treatment.
May 11, 2026
Meta-analysis finds 22.5% prevalence of Neisseria gonorrhoeae and high resistance to tetracycline, ciprofloxacin, and penicillin in Kenya
Infectious Disease Meta-analysis
Meta-analysis finds 22.5% prevalence of Neisseria gonorrhoeae and high resistance to tetracycline, ciprofloxacin, and penicillin in Kenya Kenya's Silent Gonorrhea Crisis Demands New Solutions Now
This systematic review and meta-analysis of 5,170 participants in Kenya found a pooled prevalence of Neisseria gonorrhoeae of 22.5%. Resista…
• Gonorrhea affects one in four high-risk Kenyans tested • Sex workers and low-education groups face highest danger • New treatments like ph…
May 5, 2026
Meta-analysis of antimicrobial resistance prevalence in Tanzanian hospital pathogens
Infectious Disease Meta-analysis
Meta-analysis of antimicrobial resistance prevalence in Tanzanian hospital pathogens Common Antibiotics Are Failing in Tanzania, New Data Reveals
This systematic review and meta-analysis synthesizes data from 28 studies on antimicrobial resistance in clinically relevant pathogens withi…
This research shows that common antibiotics are losing their power in Tanzania, urging a critical update to how infections are treated.
Apr 22, 2026
Short-course beta-lactam prophylaxis reduces early-onset VAP in mechanically ventilated patients with acute brain injury
Infectious Disease Meta-analysis
Short-course beta-lactam prophylaxis reduces early-onset VAP in mechanically ventilated patients with acute brain injury Short Antibiotics Cut Early Lung Infections in Brain Injury Patients
This systematic review and meta-analysis evaluated short-course systemic beta-lactam antibiotic prophylaxis versus control in 1,673 mechanic…
Short antibiotic courses cut early lung infections in brain injury patients on ventilators, reducing hospital stays without increasing death…
Apr 14, 2026
Meta-analysis finds no significant difference in outcomes between high- and low-dose ceftriaxone for non-CNS infections
Infectious Disease Meta-analysis
Meta-analysis finds no significant difference in outcomes between high- and low-dose ceftriaxone for non-CNS infections Do higher doses of a common antibiotic help adults with infections?
A meta-analysis of eight studies involving 5145 adults with non-CNS infections found no statistically significant difference in clinical cur…
Higher doses of the antibiotic ceftriaxone show no clear benefit over the standard 1-gram daily dose for curing infections in adults, based …
Apr 2, 2026