Review analyzes political drivers of PMTCT prioritization in Ghana, Mozambique, and Sudan
Strong advocacy networks drive success in ending HIV transmission to babies
This qualitative, cross-country comparative policy analysis reviews documents from Ghana, Mozambique, and Sudan to understand political prio…
United voices and reliable data help nations stop HIV from passing to newborns, but weak leadership blocks progress in some places.
Genomic analysis of 1,707 syphilis genomes reveals lineage-specific diversity and resistance markers across 11 countries
Syphilis Strains Differ Globally And This Changes Vaccine Plans
This research article presents a genomic analysis of 1,707 Treponema pallidum genomes, including 298 new sequences from 11 countries.
New genetic maps reveal syphilis bacteria changes shape by region which impacts vaccine design and drug resistance monitoring efforts global…
CSF Cytokine Panel and Machine Learning for Neurosyphilis Progression Prediction
New Test Could Catch Dangerous Syphilis Complication Early
This observational cohort study evaluated 48 cerebrospinal fluid cytokines in 129 patients with syphilis to distinguish patients from contro…
Imagine getting treated for syphilis — but months later, you start forgetting things, losing balance, or going blind.
Meta-analysis finds doxycycline prophylaxis reduces STI risk in MSM and transgender women
A Common Pill Could Slash Your Risk of Common STIs
A systematic review and meta-analysis of 14 studies in men who have sex with men and transgender women found doxycycline prophylaxis reduced…
A major review of the latest science confirms that a simple antibiotic, taken strategically, offers powerful new protection against chlamydi…
CDC issues new recommendations for diagnostic tests supporting syphilis diagnosis
What's changing in syphilis testing? New CDC recommendations aim to help doctors diagnose
The CDC has published new recommendations for diagnostic tests that can support a diagnosis of syphilis.
New CDC guidelines update how doctors diagnose syphilis to ensure clearer test results and more accurate patient care.
CDC recommends doxycycline postexposure prophylaxis for high-risk populations to prevent syphilis, chlamydia, and gonorrhea
CDC now recommends a pill after sex to help prevent common STIs
The CDC has issued clinical guidelines recommending doxycycline postexposure prophylaxis (doxy PEP) for populations at high risk for syphili…
CDC now recommends a single antibiotic pill after sex to help prevent syphilis, chlamydia, and gonorrhea in high-risk groups.
Meta-analysis finds 15.4% pooled TTI prevalence in Cameroonian blood donors, higher risk in family donors
How many blood donations in Cameroon carry dangerous infections?
A systematic review and meta-analysis of 36 studies involving approximately 105,000 blood donations in Cameroon found a pooled transfusion-t…
A new analysis of over 100,000 blood donations in Cameroon found that 15.4% carry dangerous infections like HIV, hepatitis, or syphilis, wit…
Review: New syphilis tests bridge diagnostic window but face standardization hurdles
New syphilis tests show promise for earlier detection but face standardization hurdles
A systematic review synthesizes evidence on technological innovations for syphilis diagnosis.
New syphilis tests could detect infections earlier than traditional methods, but global standardization hurdles remain before they can be wi…
Meta-analysis finds endothelial swelling and plasma cell infiltration common in secondary syphilis histology
What do syphilis skin lesions look like under the microscope? A new review finds patterns
A systematic review and meta-analysis of eight studies involving 384 patients with secondary syphilis found endothelial swelling (85% preval…
When blood tests or rashes aren't clear, doctors use skin biopsies to spot swelling in tiny blood vessels and dense white blood cell cluster…
Research across Treponemal Infections
Related studies from across the Treponemal Infections family.
Half of U.S. congenital syphilis cases linked to gaps in prenatal testing and treatment
Half of U.S. congenital syphilis cases linked to gaps in prenatal testing and treatment
An observational analysis of U.S. congenital syphilis cases found that half were associated with gaps in prenatal testing and treatment.
Half of U.S. newborn syphilis cases happen because mothers missed testing or treatment during pregnancy.
CDC report outlines syphilis testing and treatment roles for providers outside prenatal care
How can doctors outside prenatal care help stop syphilis in newborns?
A CDC Vital Signs report describes how health care providers outside of prenatal care settings can help prevent congenital syphilis in pregn…
Doctors outside prenatal care must test and treat pregnant patients for syphilis to stop deadly newborn infections, as many miss traditional…
Questions about Syphilis
How do political factors influence syphilis prevention programs in Africa?
Political factors like instability, weak governance, and uneven donor funding can disrupt syphilis prevention in Africa, while strong political commitment and advocacy improve program success.
Full answer →What new CDC tests can support a diagnosis of syphilis?
The CDC's 2024 recommendations include newer serologic tests (automated treponemal and nontreponemal tests) and molecular tests like NAATs for direct detection of T. pallidum, but no single new test replaces the need for an algorithm.
Full answer →Can doxycycline help prevent syphilis after a high-risk exposure?
Yes, taking doxycycline within 72 hours after sex can reduce the risk of syphilis by about 77% in men who have sex with men, based on clinical trials.
Full answer →