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Home › Medications › celecoxib

celecoxib

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of celecoxib

77 trials tracked of celecoxib: 32 in phase 3 or 4 and 9 with published results. The most-cited published study has 58 citations.

77Trials tracked
32Phase 3 & 4
0Recruiting
9With published results
Phase distribution
Phase 4 16 Phase 3 16 Phase 2 34 Phase 1 8 Other / NA 3
  1. Phase 3 Study of the Effect of Chondroitin Sulfate on Structural Changes in Knee Osteoarthritis Patients Assessed by MRI Completed · 58 cited
  2. Phase 4 Cyclooxygenase-2-Inhibitor Combination Treatment for Bipolar Depression Completed · 57 cited
  3. Phase 3 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis Completed · 55 cited
  4. Phase 3 European Celecoxib Trial in Primary Breast Cancer Completed · 49 cited
  5. Phase 3 Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery Completed · 45 cited
  6. Phase 4 Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Completed · 40 cited
Show 44 more trials
  1. Phase 4 Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management Completed · 11 cited
  2. Phase 3 Long Term Safety and Efficacy Study of Tanezumab in Japanese Adult Subjects With Chronic Low Back Pain Completed · 11 cited
  3. Phase 4 A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery Completed · 7 cited
  4. Phase 4 Early Diuresis Following Colorectal Surgery Completed
  5. Phase 4 Opioid-Free Shoulder Arthroplasty Completed
  6. Phase 4 MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty Completed
  7. Phase 4 Preemptive Analgesia With Celecoxib for Acute Dental Pain Management Completed
  8. Phase 4 Arginine Supplementation to Improve Cardiovascular and Endothelial Function After NSAID Treatment Completed
  9. Phase 4 Study Of Celecoxib In Healthy Subjects Completed
  10. Phase 4 Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use" Completed
  11. Phase 4 Study Of Celecoxib Or Diclofenac And Omeprazole For Gastrointestinal (GI) Safety In High GI Risk Patients With Arthritis Completed
  12. Phase 4 GI-Reasons- A Trial Of GI Safety Of Celecoxib Compared With Non-Selective Nonsteroidal Antiinflammatory Drugs (NSAIDS) Completed
  13. Phase 4 A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects Completed
  14. Phase 4 Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain Completed
  15. Phase 4 Study on Efficacy and Safety of Chondroitin Sulfate + Glucosamine Hydrochloride Versus Celecoxib in Knee Osteoarthritis Completed
  16. Phase 3 Phase III Study of CG100649 in Osteoarthritis Patients Completed
  17. Phase 3 Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy Completed
  18. Phase 3 Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen Completed
  19. Phase 3 Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction Completed
  20. Phase 3 A Six Week Study Of The Pain Relieving Effects Of Celecoxib 200 Mg Twice Daily Compared To Tramadol 50 Mg Four Times Daily In Patients With Chronic Low Back Pain Completed
  21. Phase 3 Celebrex In Acute Gouty Arthritis Study Completed
  22. Phase 3 Study of Diclofenac Capsules to Treat Pain Following Bunionectomy Completed
  23. Phase 3 Study Of Celecoxib Or Diclofenac For Efficacy and Safety In Chinese Patients With Ankylosing Spondylitis Completed
  24. Phase 3 Study of Indomethacin Capsules to Treat Pain Following Bunionectomy Completed
  25. Phase 3 Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat Completed
  26. Phase 3 An Open-Label Study Of Celecoxib In Patients With Posttraumatic Pain Completed
  27. Phase 2 Cetuximab & Celecoxib for Metastatic Colorectal Cancer or Colorectal Cancer That Cannot Be Removed by Surgery Completed
  28. Phase 2 Protocol for Women at Increased Risk of Developing Breast Cancer Completed
  29. Phase 2 Cyclophosphamide With or Without Celecoxib in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer Completed
  30. Phase 2 Celecoxib in Preventing Multiple Myeloma in Patients With Monoclonal Gammopathy or Smoldering Myeloma Completed
  31. Phase 2 Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers Completed
  32. Phase 2 Celecoxib as a Post-tonsillectomy Pain Medication Completed
  33. Phase 2 Celecoxib and Radiation Therapy in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer Completed
  34. Phase 2 Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors Completed
  35. Phase 2 Radiosensitization With Celecoxib and Chemoradiation for Head and Neck Cancer Completed
  36. Phase 2 Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia Completed
  37. Phase 2 Study of CG100649 Versus Celecoxib in Osteoarthritis Patients Completed
  38. Phase 2 PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery Completed
  39. Phase 2 Celecoxib and Recombinant Interferon Alfa-2b in Metastatic Kidney Cancer Who Have Undergone Surgery Completed
  40. Phase 2 Celecoxib After Tonsillectomy Completed
  41. Phase 2 Open-Label CA-008 (Vocacapsaicin) in Bunionectomy Completed
  42. Phase 2 Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver Completed
  43. Phase 2 A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale Completed
  44. Phase 2 Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers Completed

Showing the 50 most-cited and recently-updated of 77 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Celecoxib ranks highest for analgesic efficacy in patients with knee osteoarthritis
Orthopedics & Sports Medicine Meta-analysis
Celecoxib ranks highest for analgesic efficacy in patients with knee osteoarthritis Comparing Different Medications and Supplements to Manage Knee Osteoarthritis Pain
This network meta-analysis compared several interventions, including celecoxib, metformin, and krill oil, for the management of knee osteoar…
Doctors are looking at several ways to treat knee pain. This review compares drugs like celecoxib with natural options like krill oil.
Frontiers Jul 22, 2026
AI plus celecoxib more than doubles odds of clinical response in ER-positive breast cancer
Oncology RCT
AI plus celecoxib more than doubles odds of clinical response in ER-positive breast cancer Adding celecoxib to hormone therapy improves early breast cancer response
This Phase III randomized trial of 269 postmenopausal women with ER-positive resectable breast cancer found that adding celecoxib to an arom…
A new trial shows that adding the drug celecoxib to standard hormone therapy can improve initial clinical responses in postmenopausal women …
medRxiv Jul 18, 2026
Acupuncture and Celecoxib for Chronic Knee Pain: Genetic Factors May Influence Response
Anesthesiology & Pain Medicine RCT
Acupuncture and Celecoxib for Chronic Knee Pain: Genetic Factors May Influence Response New Gene Test Predicts Who Gets Pain Relief From Acupuncture
This randomized trial compared verum acupuncture, sham acupuncture, celecoxib, placebo, and waiting list in 180 patients with chronic knee p…
A new gene test might help doctors know if acupuncture will actually stop your knee pain before you start treatment.
Apr 30, 2026
Network meta-analysis of pharmacological interventions for hand-foot syndrome in cancer patients undergoing chemotherapy
Oncology Meta-analysis
Network meta-analysis of pharmacological interventions for hand-foot syndrome in cancer patients undergoing chemotherapy Simple cream could stop painful hand and foot syndrome side effects
This network meta-analysis evaluated pharmacological interventions for hand-foot syndrome prevention in cancer patients undergoing chemother…
New research suggests a common pain cream could protect cancer patients from painful hand and foot syndrome during treatment.
Apr 29, 2026
Oral celecoxib plus flurbiprofen hydrogel patch improves lateral epicondylitis outcomes versus celecoxib alone in a retrospective cohort
Drug Pipeline Cohort
Oral celecoxib plus flurbiprofen hydrogel patch improves lateral epicondylitis outcomes versus celecoxib alone in a retrospective cohort Pain Relief for Tennis Elbow Gets a Boost
This retrospective cohort analysis included 64 patients with lateral epicondylitis comparing oral celecoxib combined with flurbiprofen hydro…
A new patch combined with pills reduces tennis elbow pain and inflammation faster than pills alone, offering quicker relief for stubborn elb…
Frontiers Apr 19, 2026