Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
New trial to test azithromycin vs doxycycline for pneumonia
This is a protocol for a planned randomized clinical trial involving 1120 adult patients hospitalized with community-acquired pneumonia. No …
A large trial will compare two antibiotic combos for hospitalized pneumonia patients. Which works better?
Metagenomic sequencing identifies Rickettsia felis encephalitis in a child who fully recovered
Rare Cat Flea Bacteria Causes Encephalitis in Child
This case report and literature review describes a 9-year-old boy with R. felis encephalitis diagnosed via metagenomic next-generation seque…
A 9-year-old boy's severe brain infection was caused by a rare cat flea bacteria, not a virus. He recovered after targeted treatment.
Vonoprazan-amoxicillin dual therapy is a safe alternative to bismuth-containing quadruple therapy for H. pylori
New vonoprazan treatments show promise for clearing H. pylori infection
This multicenter randomized controlled trial of 579 H. pylori-positive patients found that vonoprazan-amoxicillin (VA) dual therapy demonstr…
Two new simplified drug combinations could offer a simpler way to clear H. pylori infections, especially for patients with certain allergies…
Doxycycline provides higher odds of microbiological cure compared to azithromycin in cis-men with chlamydia
Doxycycline Shows Higher Cure Rates for Chlamydia in Men
This systematic review and meta-analysis of 1172 patients found that doxycycline (OR = 2.525, 95% CI: 1.329-4.796, p = 0.005) provides a hig…
A review of clinical data suggests doxycycline may be more effective than azithromycin for treating chlamydia infections in men.
Case report on Brucella periprosthetic joint infection after knee replacement
Two rare knee infections treated with specific antibiotics and surgery
This is a case report of two patients with Brucella-induced periprosthetic joint infection after total knee arthroplasty. The authors descri…
Two patients with rare Brucella knee infections saw normal markers and restored motion after targeted antibiotic therapy and surgery.
Systematic review and meta-analysis compares oral azithromycin and doxycycline for moderate to severe acne
Azithromycin may work better than doxycycline for some acne cases
This systematic review and meta-analysis synthesized evidence on oral azithromycin pulse therapy versus doxycycline for moderate to severe a…
A new review finds azithromycin pulse therapy may improve acne more than doxycycline, with fewer side effects for some patients.
Narrative review suggests phytochemicals and phages may augment conventional antibiotics for brucellosis
New plant-based and phage options might help treat stubborn brucellosis infections in people and animals
This narrative review discusses novel strategies for treating brucellosis in humans and animals. The authors note that conventional antibiot…
Standard antibiotics sometimes fail to cure brucellosis, and bacteria are becoming resistant. New methods using plant chemicals and viruses …
Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
Testing for resistance genes may guide antibiotic choices
This retrospective cohort study of 150 children with Mycoplasma pneumoniae pneumonia evaluated resistance gene expression and antibiotic man…
New evidence suggests that checking for resistance genes in children with pneumonia could help doctors decide when to switch antibiotics.
Meta-analysis finds doxycycline prophylaxis reduces STI risk in MSM and transgender women
A Common Pill Could Slash Your Risk of Common STIs
A systematic review and meta-analysis of 14 studies in men who have sex with men and transgender women found doxycycline prophylaxis reduced…
A major review of the latest science confirms that a simple antibiotic, taken strategically, offers powerful new protection against chlamydi…
Doxycycline-Quinolone Sequential Therapy Shows Lower Failure, Recurrence vs Azithromycin for MG
A New Strategy Cures a Stubborn STD Faster and Prevents Its Return
A retrospective cohort study of 1,192 NAAT-confirmed MG patients at a Chinese tertiary hospital found doxycycline-quinolone sequential thera…
Doctors now have clearer evidence for a better treatment plan to defeat a common, often-missed sexually transmitted infection.
Guidelines outline antimicrobial treatment and prophylaxis recommendations for human plague
Health experts issue updated treatment guidelines for plague infections
A guideline document provides recommended best practices for antimicrobial treatment and prophylaxis of human plague in naturally acquired i…
Updated guidelines now tell doctors how to treat and prevent plague infections from natural outbreaks or bioterrorism attacks.
CDC recommends doxycycline postexposure prophylaxis for high-risk populations to prevent syphilis, chlamydia, and gonorrhea
CDC now recommends a pill after sex to help prevent common STIs
The CDC has issued clinical guidelines recommending doxycycline postexposure prophylaxis (doxy PEP) for populations at high risk for syphili…
CDC now recommends a single antibiotic pill after sex to help prevent syphilis, chlamydia, and gonorrhea in high-risk groups.