Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
Testing for resistance genes may guide antibiotic choices
This retrospective cohort study of 150 children with Mycoplasma pneumoniae pneumonia evaluated resistance gene expression and antibiotic man…
New evidence suggests that checking for resistance genes in children with pneumonia could help doctors decide when to switch antibiotics.
Machine Learning Algorithms Predict Plastic Bronchitis in Pediatric Mycoplasma Pneumonia Patients
Can a computer spot a deadly lung condition before it starts?
This retrospective cohort study of 307 pediatric patients with Mycoplasma pneumoniae pneumonia evaluated machine learning algorithms for pre…
A new computer program can spot a rare, life-threatening lung condition in children much earlier than current methods allow.
Clinical indicators predict refractory Mycoplasma pneumoniae pneumonia in children
New Tool Predicts Which Kids Need Stronger Pneumonia Treatment
This retrospective case–control analysis evaluated 522 children with Mycoplasma pneumoniae pneumonia (MPP) to identify predictors of refract…
This new model gives doctors a simple way to identify children with pneumonia who might need stronger treatment right away.
Higher CRP and D-dimer levels associated with cerebral infarction in children with Mycoplasma pneumoniae pneumonia
High Fever Warning: Two Blood Tests Spot Stroke Risk in Kids
This retrospective cohort study included 2,947 children diagnosed with Mycoplasma pneumoniae pneumonia.
Two simple blood tests can spot stroke risk in kids with pneumonia before brain damage happens, helping doctors catch rare cases early.
Review of a case report on necrotizing laryngotracheobronchitis after Mycoplasma pneumoniae pneumonia
Could a common infection trigger a rare, severe throat condition in a young boy?
This review summarizes a case report of a 7-year-old boy with necrotizing laryngotracheobronchitis following Mycoplasma pneumoniae pneumonia…
A common respiratory bug turned a seven-year-old boy's throat infection into a rare, severe condition requiring multiple airway washes to re…
PBMC gene expression profiles differentiate refractory Mycoplasma pneumoniae pneumonia in children
New Blood Test Distinguishes Severe Lung Infection Early
This cohort study of 349 children identified peripheral blood mononuclear cell gene expression profiles as potential biomarkers for refracto…
A new four-gene blood test helps doctors spot severe, hard-to-treat pneumonia in children before symptoms get too bad to fix easily.
Atopic constitution associated with severe Mycoplasma pneumoniae pneumonia in children
Why Allergy-Prone Kids Get Sicker From This Common Lung Infection
This retrospective cohort study examined 377 children with Mycoplasma pneumoniae pneumonia at Wuhan Children's Hospital.
Allergy-prone children face a higher risk of severe pneumonia from Mycoplasma, and two simple blood tests could flag who needs closer watchi…
Retrospective study links IVIG plus azithromycin to higher response rate in pediatric Mycoplasma pneumoniae pneumonia
When a Child's Pneumonia Won't Clear, This Add-On May Help
A single-center retrospective cohort of 140 children with Mycoplasma pneumoniae pneumonia found that adding intravenous immunoglobulin (IVIG…
Adding donor antibodies to standard antibiotics helped 97% of children with stubborn pneumonia recover, compared to 84% on antibiotics alone…
Retrospective study identifies CRP, pleural effusion, and LDH as risk factors for plastic bronchitis in children with refractory M. pneumoniae pneumonia
Study identifies three risk factors for plastic bronchitis in children with severe pneumonia
A retrospective cohort study of 205 hospitalized children with refractory Mycoplasma pneumoniae pneumonia found that 25.4% (52 patients) dev…
Doctors found three warning signs in children with severe pneumonia that predict a dangerous airway complication called plastic bronchitis.
U.S. pediatric hospitals report increase in Mycoplasma pneumoniae pneumonia discharges in children
Report notes increase in childhood pneumonia hospitalizations linked to Mycoplasma bacteria
An observational report from U.S. pediatric hospitals indicates an increase in hospital discharges of children with Mycoplasma pneumoniae-as…
U.S. pediatric hospitals saw more children hospitalized for Mycoplasma pneumonia in 2024, signaling a pattern health officials are watching.
Research across Pneumonia
Related studies from across the Pneumonia family.
Autoantibody positivity and false-negative cytology can mask invasive mucinous adenocarcinoma in patients with IPAF
Lung cancer can mimic autoimmune lung disease in some patients
This case report describes a 78-year-old female with invasive mucinous adenocarcinoma and interstitial pneumonia with autoimmune features. T…
A new case shows how a rare lung cancer can look like an autoimmune disease, making it hard for doctors to tell them apart.
MRSA nares PCR does not cut vancomycin duration in ICU CAP
MRSA Testing Does Not Reduce Vancomycin Use in Pneumonia Patients
In a single-center randomized trial of 277 adult ICU patients with suspected community-acquired pneumonia, MRSA nares PCR testing did not si…
A trial of 277 ICU patients found that MRSA nasal swab testing did not reduce the amount of vancomycin used for pneumonia.
Physical frailty tops risk factors for pneumonia after esophagectomy, meta-analysis finds
Physical frailty and muscle loss increase pneumonia risk after surgery
This meta-analysis of 60 cohort studies in esophageal cancer patients undergoing esophagectomy identified physical frailty as the highest-ra…
Patients with esophageal cancer face a higher risk of pneumonia after surgery if they show signs of physical frailty or muscle loss.
Short-course ceftriaxone reduces hospital stay and adverse events in children with pneumonia
Shorter antibiotic courses may help children with pneumonia stay home
This randomized controlled trial of 200 children aged 1 to 14 years found that short-course ceftriaxone (5 to 7 days) resulted in shorter ho…
A new trial shows that a shorter course of ceftriaxone can reduce hospital stays and side effects for children with pneumonia.
Aerosolized liposomal amphotericin B provides strongest evidence for invasive pulmonary aspergillosis prophylaxis in high-risk patients
Aerosolized Amphotericin B Shows Promise for Lung Fungal Infections
This mini review synthesizes clinical experience regarding aerosolized antifungal therapies for various pulmonary fungal infections. It conc…
Aerosolized liposomal amphotericin B shows promise for preventing specific lung fungal infections in high-risk and immunocompromised patient…
mNGS achieves 85.83% pathogen detection rate in children with severe pneumonia compared to 49.97% for conventional methods
New Genetic Test Finds More Pneumonia Germs in Kids
This systematic review evaluates metagenomic next-generation sequencing (mNGS) for identifying pathogens in children with severe pneumonia. …
A new genetic test detects pneumonia-causing germs in kids more often than standard methods, which could lead to better treatment.
Inhaled antibiotics may improve lung function and microbiological eradication in cystic fibrosis and bronchiectasis
Inhaled Antibiotics May Improve Lung Health in Chronic Lung Conditions
This meta-analysis evaluated the efficacy of inhaled antibiotics for patients with cystic fibrosis, non-cystic fibrosis bronchiectasis, and …
Inhaled antibiotics may improve lung function and clear infections for people with cystic fibrosis and other chronic lung conditions.
Antibiotic exposure disrupts gut microbiota in 58% to 94% of critically ill children
Antibiotics and gut health in critically ill children
This narrative review examines antibiotic exposure in critically ill children in the PICU, reporting that 58% to 94% receive antibiotics, wh…
Common antibiotics used in intensive care can disrupt a child's gut health, increasing the risk of serious infections like pneumonia.
iNKT cell activators show promise in preclinical models for stroke-associated pneumonia immunomodulation
New immune treatments show promise for stroke and pneumonia
This systematic review of 38 preclinical studies examines the immunopathology of stroke-associated pneumonia (SAP) and the role of immunomod…
Researchers identify how stroke triggers immune failure and find a promising new way to protect the lungs from pneumonia infections.
IL-6 overexpression linked to alveolar damage in severe pneumonia on ventilation
IL-6 Levels Linked to Lung Damage in Severe Pneumonia
This narrative review synthesizes basic and clinical evidence on IL-6 in mechanically ventilated patients with severe pneumonia. It finds th…
High levels of a protein called IL-6 may be linked to increased lung damage and inflammation in patients with severe pneumonia.
Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia
Low dose steroids may lower death rates in severe lung infections
This meta-analysis of 4,622 patients found that low-dose corticosteroids (≤400 mg hydrocortisone-equivalent daily) significantly reduced sho…
A review of clinical trials suggests that low-dose corticosteroids can reduce 90-day mortality for adults with severe lung infections like p…
Oral amoxicillin or amoxicillin-clavulanate is non-inferior to intravenous treatment for severe CAP in children
Trial shows oral antibiotics work for children with severe pneumonia
This randomized controlled trial of 1,101 children with severe community-acquired pneumonia in sub-Saharan Africa found that step-down oral …
A large trial in Africa found that switching children from IV to oral antibiotics for pneumonia is as safe and effective as staying on IV tr…
Questions about Mycoplasma pneumoniae pneumonia
Does having pleural effusion increase the risk of refractory Mycoplasma pneumoniae pneumonia?
Yes, multiple studies and meta-analyses consistently identify pleural effusion as an independent risk factor for refractory Mycoplasma pneumoniae pneumonia in children.
Full answer →What clinical indicators predict refractory Mycoplasma pneumoniae pneumonia in children?
Doctors can predict refractory Mycoplasma pneumoniae pneumonia in children using specific signs like long fever duration, lung complications like pleural effusion, and high levels of inflammatory markers like CRP and LDH.
Full answer →Is an atopic constitution linked to severe Mycoplasma pneumoniae pneumonia in children?
Yes, atopic constitution is linked to severe Mycoplasma pneumoniae pneumonia in children, with 74.8% of affected children having atopy and 7.1% progressing to severe disease.
Full answer →Can a case report explain necrotizing laryngotracheobronchitis after Mycoplasma pneumoniae pneumonia?
Yes, a case report can describe necrotizing laryngotracheobronchitis after Mycoplasma pneumoniae pneumonia, as shown in a detailed case of a 7-year-old boy.
Full answer →What clinical indicators predict refractory Mycoplasma pneumoniae pneumonia in children?
Key predictors of refractory Mycoplasma pneumoniae pneumonia in children include prolonged fever, high CRP, high neutrophil-to-lymphocyte ratio, pleural effusion, atelectasis, and extrapulmonary complications.
Full answer →Can switching from azithromycin to doxycycline help children with Mycoplasma pneumoniae pneumonia?
Yes, switching from azithromycin to doxycycline can help children with Mycoplasma pneumoniae pneumonia, especially when macrolide resistance is suspected or the child does not improve after 72 hours of azithromycin.
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