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Home › Medications › levofloxacin

levofloxacin

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of levofloxacin

23 trials tracked of levofloxacin: 12 in phase 3 or 4 and 5 with published results. The most-cited published study has 402 citations.

23Trials tracked
12Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 4 Phase 3 8 Phase 2 10 Other / NA 1
  1. Phase 3 The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB Completed · 402 cited
  2. Phase 3 Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP Completed · 306 cited
  3. Phase 4 Quinolone Prophylaxis for the Prevention of BK Virus Infection in Kidney Transplantation: A Pilot Study Completed · 123 cited
  4. Phase 3 TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial Completed · 102 cited
  5. Phase 4 BK Treatment Study Completed · 94 cited
  6. Phase 4 Pharmacodynamic of Ceftaroline and Levofloxacin Against Pathogens Associated With Community Acquired Bacterial Pneumonia Completed
Show 17 more trials
  1. Phase 4 A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms Completed
  2. Phase 3 Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Completed
  3. Phase 3 Efficacy and Safety Study of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections Completed
  4. Phase 3 Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Participants With Complicated Urinary Tract Infections Completed
  5. Phase 3 Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis Completed
  6. Phase 3 An Effectiveness and Safety Study for Levofloxacin in Chronic Prostatitis Completed
  7. Phase 2 Treatment Shortening of MDR-TB Using Existing and New Drugs Completed
  8. Phase 2 Topical Antibiotics in Chronic Rhinosinusitis Completed
  9. Phase 2 Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis Completed
  10. Phase 2 Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis Completed
  11. Phase 2 Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB Completed
  12. Phase 2 Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With a Mild Infection of a Foot Ulcer Completed
  13. Phase 2 IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute Pyelonephritis Completed
  14. Phase 2 Ciprofloxacin Versus Levofloxacin in Stem Cell Transplant Completed
  15. Phase 2 Evaluation Of Aqueous Humor Of Levofloxacin-Dexamethasone Eye Drops And Of Its Components In Patients Undergoing Cataract Surgery Completed
  16. Phase 2 A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) Completed
  17. N/A Healthy Patients & Effect of Antibiotics Completed

Showing the 23 most-cited and recently-updated of 23 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Susceptibility-guided sequential therapy shows no superiority over empirical therapy for H. pylori eradication
Infectious Disease RCT
Susceptibility-guided sequential therapy shows no superiority over empirical therapy for H. pylori eradication Susceptibility-guided therapy did not beat standard treatment for stomach bug infections
This randomised controlled trial in 500 treatment-naive adults with H. pylori infection compared susceptibility-guided sequential therapy to…
A new trial found that testing for drug resistance before treatment did not improve cure rates compared to standard care for stomach infecti…
Jun 1, 2026
Meta-analysis finds high fluoroquinolone resistance in E. coli causing UTIs globally
Infectious Disease Meta-analysis
Meta-analysis finds high fluoroquinolone resistance in E. coli causing UTIs globally 1 in 3 UTI E. coli cases now resist common antibiotics
This meta-analysis of 36 studies reports a pooled fluoroquinolone resistance prevalence of 31.09% in E. coli from UTIs. Resistance varied by…
A global review finds that nearly a third of E. coli from UTIs are resistant to key fluoroquinolone antibiotics, making infections harder to…
Frontiers May 25, 2026
Meta-analysis finds fluoroquinolone prophylaxis reduces febrile neutropenia in pediatric ALL
Oncology Meta-analysis
Meta-analysis finds fluoroquinolone prophylaxis reduces febrile neutropenia in pediatric ALL Fluoroquinolone antibiotics lower febrile neutropenia risk in children with acute lymphoblastic leukemia during treatment start
This systematic review and meta-analysis of 991 children with acute lymphoblastic leukemia found that fluoroquinolone prophylaxis reduced fe…
A review of children with acute lymphoblastic leukemia shows fluoroquinolone antibiotics reduce febrile neutropenia risk. This finding sugge…
May 1, 2026
Molecular epidemiology study of rifampicin-resistant TB in Vietnam shows high resistance to other drugs
Infectious Disease
Molecular epidemiology study of rifampicin-resistant TB in Vietnam shows high resistance to other drugs Vietnam’s TB Crisis Hides a Dangerous Pattern
This molecular epidemiology study analyzed 252 rifampicin-resistant TB isolates from Vietnam using whole genome sequencing.
A hidden pattern in Vietnam’s tuberculosis cases reveals most drug-resistant strains also resist other key medicines, changing how doctors m…
medRxiv Apr 27, 2026
Review of ESBL-producing E. coli epidemiology and fluoroquinolone resistance in Mexican community isolates
Infectious Disease
Review of ESBL-producing E. coli epidemiology and fluoroquinolone resistance in Mexican community isolates UTIs Are Getting Harder to Treat — Here’s Why
This retrospective cross-sectional study reviews community-acquired E.
This could change how doctors choose antibiotics for UTIs.
medRxiv Apr 23, 2026