Bismuth quadruple and concomitant regimens achieve >85% H. pylori eradication amid rising clarithromycin resistance
H. pylori treatments failing as resistance grows, review finds
This narrative review synthesizes current H. pylori eradication strategies, noting that clarithromycin resistance exceeds 15%-20% in most re…
Clarithromycin resistance now tops 15-20% in most regions, but bismuth quadruple and other combos still clear the bug over 85% of the time.
Antibiotic resistance mutations drive H. pylori treatment failure across Asia-Pacific region
Antibiotic resistance in H. pylori rising across Asia
This meta-analysis of H. pylori infections in the Asia-Pacific region finds that clarithromycin resistance (19-34%) is driven by A2142G/A214…
H. pylori bacteria in Asia are increasingly resistant to common antibiotics, driven by specific mutations.
6-month bedaquiline, linezolid, delamanid, and levofloxacin or clofazimine regimen is noninferior to 9-month standard care
Trial shows shorter treatment works for resistant tuberculosis
This Phase 3 randomized controlled noninferiority trial evaluated a 6-month treatment strategy for pulmonary rifampicin-resistant tuberculos…
A new six-month treatment plan for drug-resistant tuberculosis showed similar success rates to the standard nine-month course.
Susceptibility-guided sequential therapy shows no superiority over empirical therapy for H. pylori eradication
Susceptibility-guided therapy did not beat standard treatment for stomach bug infections
This randomised controlled trial in 500 treatment-naive adults with H. pylori infection compared susceptibility-guided sequential therapy to…
A new trial found that testing for drug resistance before treatment did not improve cure rates compared to standard care for stomach infecti…
Meta-analysis finds high fluoroquinolone resistance in E. coli causing UTIs globally
1 in 3 UTI E. coli cases now resist common antibiotics
This meta-analysis of 36 studies reports a pooled fluoroquinolone resistance prevalence of 31.09% in E. coli from UTIs. Resistance varied by…
A global review finds that nearly a third of E. coli from UTIs are resistant to key fluoroquinolone antibiotics, making infections harder to…
Meta-analysis finds fluoroquinolone prophylaxis reduces febrile neutropenia in pediatric ALL
Fluoroquinolone antibiotics lower febrile neutropenia risk in children with acute lymphoblastic leukemia during treatment start
This systematic review and meta-analysis of 991 children with acute lymphoblastic leukemia found that fluoroquinolone prophylaxis reduced fe…
A review of children with acute lymphoblastic leukemia shows fluoroquinolone antibiotics reduce febrile neutropenia risk. This finding sugge…
Molecular epidemiology study of rifampicin-resistant TB in Vietnam shows high resistance to other drugs
Vietnam’s TB Crisis Hides a Dangerous Pattern
This molecular epidemiology study analyzed 252 rifampicin-resistant TB isolates from Vietnam using whole genome sequencing.
A hidden pattern in Vietnam’s tuberculosis cases reveals most drug-resistant strains also resist other key medicines, changing how doctors m…
Review of ESBL-producing E. coli epidemiology and fluoroquinolone resistance in Mexican community isolates
UTIs Are Getting Harder to Treat — Here’s Why
This retrospective cross-sectional study reviews community-acquired E.
This could change how doctors choose antibiotics for UTIs.