Predictive nomogram identifies suboptimal valproate concentrations in pediatric epilepsy patients using daily dose, organ injury, and meropenem.
New tool predicts dangerous valproate levels in children with epilepsy
This retrospective cohort study of 121 pediatric patients with epilepsy aged 2–18 years developed a predictive nomogram to identify suboptim…
A new calculator can flag children with epilepsy who are likely to get unsafe valproate levels, helping doctors adjust doses before problems…
Brief research report on toxicity-guided TMP-SMX dose reduction in disseminated nocardiosis.
Gold miner's rare infection treated with adjusted antibiotic dose
This brief research report describes a single case of disseminated nocardiosis with CNS involvement in a patient with pneumoconiosis. The ma…
A gold miner with a rare brain infection improved after doctors lowered his antibiotic dose due to severe side effects.
Meta-analysis of antimicrobial resistance prevalence in Tanzanian hospital pathogens
Common Antibiotics Are Failing in Tanzania, New Data Reveals
This systematic review and meta-analysis synthesizes data from 28 studies on antimicrobial resistance in clinically relevant pathogens withi…
This research shows that common antibiotics are losing their power in Tanzania, urging a critical update to how infections are treated.
Retrospective cohort study assesses Acinetobacter baumannii prevalence and resistance in ventilator-associated infections.
ICU Infection Risk Skyrockets Without Local Drug Data
This retrospective observational cohort analyzed 3,540 non-duplicate clinical isolates from a tertiary-care ICU in South India. The study ev…
ICU patients with breathing tubes face higher infection risks when doctors lack fresh local data on which antibiotics actually work against …