Higher admission WBC predicts favorable methylprednisolone effect after thrombectomy
Higher white blood cell counts linked to better methylprednisolone effects in stroke patients
This secondary analysis of a randomized, placebo-controlled trial evaluated 1201 patients with anterior-circulation large-vessel occlusion s…
A secondary analysis suggests higher white blood cell counts may predict better outcomes when adding methylprednisolone to stroke treatment …
Rituximab rechallenge caused severe hypersensitivity reaction in a patient with membranous nephropathy
A third Rituximab dose caused severe shock in a man with kidney disease
This case report describes a 52-year-old male with biopsy-proven primary membranous nephropathy who received a third 1 g infusion of rituxim…
A man with kidney disease developed life-threatening shock after a third Rituximab infusion, highlighting the need for careful monitoring an…
Review of ruxolitinib for systemic juvenile arthritis with macrophage activation syndrome
Two children with severe arthritis found relief using a new drug approach
This narrative review synthesizes a retrospective case series and literature search on ruxolitinib for systemic juvenile idiopathic arthriti…
Two children with severe arthritis complications found relief using a new drug approach, offering hope for those who struggle with standard …
Case report and review on autoimmune nodopathy with Sjogren's disease and nephrotic syndrome
A rare case report shows intravenous methylprednisolone therapy improved neurological symptoms in a woman with autoimmune nodopathy
This is a case report and literature review on a 45-year-old woman with autoimmune nodopathy, Sjogren's disease, and nephrotic syndrome. The…
A 45-year-old woman with autoimmune nodopathy saw her neurological symptoms improve significantly after receiving intravenous methylpredniso…
Songjiao Dihuang Tang for Immune Checkpoint Inhibitor-Associated Myocarditis: Trial Protocol
Chinese herbal formula tested for immunotherapy heart side effect
This protocol describes a multicenter, double-blind RCT of Songjiao Dihuang Tang plus standard care vs placebo in 200 patients with mild ICI…
A new trial will test if a traditional Chinese herbal formula can protect cancer patients from a rare but serious heart complication caused …
Case report and literature review of severe adverse reactions following pucotenlimab treatment
New drug treatment linked to severe neurological reactions
This case report and literature review describes severe adverse reactions following treatment with pucotenlimab in a patient with advanced b…
A single patient facing advanced breast cancer experienced life-threatening neurological symptoms after receiving the drug pucotenlimab.
Case report describes sintilimab-associated toxic epidermal necrolysis in gastric carcinoma patient
Rare Skin Reaction Follows Successful Stomach Cancer Therapy
This case report details a patient with gastric carcinoma developing delayed-onset toxic epidermal necrolysis during neoadjuvant sintilimab …
A new case shows a common stomach cancer drug can cause dangerous skin reactions even after surgery.
Retrospective review of methylprednisolone response in children with TBX4-associated pulmonary hypertension and interstitial lung disease
Pulsed steroids may help children with TBX4-linked lung disease and pulmonary hypertension
This review examines a retrospective cohort of 21 children with TBX4-associated pulmonary hypertension treated with methylprednisolone.
Pulsed steroids helped most children with TBX4-linked lung disease improve breathing and heart function without significant side effects.
Case Report Details Aumolertinib Rechallenge Following Osimertinib-Induced Interstitial Lung Disease in Lung Adenocarcinoma
Can lung cancer drugs be restarted after severe lung injury?
This case report describes a 73-year-old male with stage IV lung adenocarcinoma and EGFR exon 19 deletions who experienced interstitial lung…
Doctors successfully restarted a powerful lung cancer drug after a patient's lungs healed from a dangerous reaction to the first one.
Infliximab in IVIG-resistant Kawasaki disease with cholestatic hepatitis: case report
Can a new drug stop heart damage in Kawasaki disease when standard treatments fail?
A case report describes a 2-year-old Han Chinese male with IVIG-resistant Kawasaki disease and cholestatic hepatitis treated with infliximab…
In a two-year-old boy with Kawasaki disease, the drug infliximab quickly stopped his fever and liver trouble, yet his heart artery damage ke…
Hospitalized AE-RA-ILD patients receiving JAK inhibitors alongside glucocorticoids showed mixed respiratory outcomes over three months
A Rheumatoid Arthritis Drug May Help Save Lungs in Crisis
This retrospective observational case series examined six consecutive patients hospitalized for acute exacerbation of rheumatoid arthritis–a…
A small study suggests a familiar arthritis pill may help calm sudden, dangerous lung flare-ups in people with rheumatoid arthritis.
Subcutaneous etanercept rapidly alleviated pain and inflammation in 12 acute gout patients compared to methylprednisolone
Small study finds etanercept may help acute gout pain like steroids
This single-center, prospective, randomized, open-label study evaluated subcutaneous etanercept versus intravenous methylprednisolone in 12 …
A small study found etanercept provided rapid pain relief for acute gout flares that matched standard steroid treatment with no serious side…