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Allergy & Immunology
Sys. Review
Review of case report discusses anti-PL-12 antisynthetase syndrome and NK/T-cell non-Hodgkin lymphoma
Patient with anti-PL-12 syndrome and lymphoma: a rare case report
This review of a case report describes a patient with anti-PL-12 antisynthetase syndrome and NK/T-cell non-Hodgkin lymphoma. The authors not…
A single patient with anti-PL-12 antisynthetase syndrome and NK/T-cell lymphoma highlights the need for caution when interpreting rare cance…
Frontiers
Apr 24, 2026
Drug Pipeline
Cohort
Rituximab use in interstitial pneumonia with autoimmune features shows similar outcomes to control group
Rituximab shows similar outcomes for IPAF patients in small study
This retrospective case-control study of 14 rituximab-treated and 19 control patients with interstitial pneumonia with autoimmune features f…
A small study found that patients with a rare lung condition had similar outcomes whether they received rituximab or not, suggesting limited…
Frontiers
Apr 24, 2026
Pulmonology & Critical Care
Retrospective review of methylprednisolone response in children with TBX4-associated pulmonary hypertension and interstitial lung disease.
Pulsed steroids may help children with TBX4-linked lung disease and pulmonary hypertension
This review examines a retrospective cohort of 21 children with TBX4-associated pulmonary hypertension treated with methylprednisolone. Auth…
Pulsed steroids helped most children with TBX4-linked lung disease improve breathing and heart function without significant side effects.
medRxiv
Apr 20, 2026
Drug Pipeline
Guideline
Case Report Details Aumolertinib Rechallenge Following Osimertinib-Induced Interstitial Lung Disease in Lung Adenocarcinoma
Can lung cancer drugs be restarted after severe lung injury?
This case report describes a 73-year-old male with stage IV lung adenocarcinoma and EGFR exon 19 deletions who experienced interstitial lung…
Doctors successfully restarted a powerful lung cancer drug after a patient's lungs healed from a dangerous reaction to the first one.
Frontiers
Apr 19, 2026
Rheumatology
Cohort
Relaxation training and early benzodiazepines linked to respiratory recovery in adults with COPD, pneumonia, asthma, bronchiectasis, or interstitial lung disease.
Could early sedatives be slowing down lung recovery for adults with breathing problems?
This retrospective observational study examined 389 consecutive adults (≥ 18 years) admitted with chronic obstructive pulmonary disease, pne…
Early sedatives given to adults with breathing problems may slow lung recovery, making it harder for patients to improve before leaving the …
Frontiers
Apr 18, 2026
Allergy & Immunology
Meta-analysis
Male sex and advanced age associated with higher risk of RP-ILD in anti-MDA5 dermatomyositis patients.
Some Patients With This Rare Lung-Muscle Disease Face Faster Decline
This systematic review and meta-analysis of 15 studies evaluated factors associated with rapidly progressive interstitial lung disease (RP-I…
Men and older adults with a rare autoimmune lung disease are at higher risk of rapid, life-threatening lung damage, a new review finds.
Frontiers
Apr 16, 2026
Rheumatology
Cohort
Inflammatory and metabolic markers differ across systemic sclerosis lung phenotypes in retrospective study
Scleroderma Lung Damage May Leave Hidden Clues in Blood
A retrospective cross-sectional study of 314 SSc inpatients found higher inflammatory markers (ESR, hs-CRP, CRP/albumin ratio, SII) and anti…
Routine blood tests may soon reveal hidden lung damage patterns in scleroderma patients, helping doctors spot dangerous complications before…
Frontiers
Apr 16, 2026
Gastroenterology
RCT
Narrative review outlines clinical framework for managing primary Sjögren's disease with interstitial lung disease
New Hope for Sjögren's Patients with Lung Scarring
A narrative review synthesizes evidence on managing primary Sjögren's disease with interstitial lung disease, highlighting a pragmatic clini…
Lung scarring in Sjögren's disease can be deadly, but new strategies targeting specific disease patterns offer a path forward for patients.
Frontiers
Apr 15, 2026
Primary Care & Family Medicine
Sys. Review
Narrative review links rare earth element exposure to respiratory symptoms and lung disease in industrial settings.
Tiny Dust, Big Lungs: The Hidden Air Threat
This narrative review synthesizes evidence regarding environmental exposure to rare earth elements (REEs) in mining and industrial regions. …
The dust inside your favorite gadgets and phones might be quietly damaging your lungs without you even knowing it.
Frontiers
Apr 15, 2026
Pulmonology & Critical Care
Spirometry restriction linked to higher interstitial lung disease and mortality risk in a large cohort.
Does normal breathing test results hide serious lung disease that leads to higher death rates?
This retrospective cohort study of 47,597 patients with normal spirometry from four pulmonary diagnostic labs found that spirometry restrict…
A normal breathing test might hide a serious lung problem that makes you three times more likely to develop scarring and 45% more likely to …
medRxiv
Apr 14, 2026
Oncology
Cohort
Interstitial lung disease reduces achievement of rheumatoid arthritis treatment goals over 24 months
Why Interstitial Lung Disease Blocks Rheumatoid Arthritis Goals
This retrospective cohort study examined 254 patients with newly diagnosed rheumatoid arthritis who underwent chest CT within one year of on…
Rheumatoid arthritis treatments often fail to reach pain-free goals when the disease also attacks the lungs, making standard care harder for…
Frontiers
Apr 11, 2026
Rheumatology
Cohort
Higher systemic immune-inflammation index associated with increased mortality in interstitial lung disease
Could a simple blood test help predict survival in serious lung disease?
A retrospective cohort study of 366 patients with interstitial lung disease found that a higher systemic immune-inflammation index (SII) was…
A simple blood test number linked to higher death risk could help doctors predict survival for patients with serious lung scarring.
Frontiers
Apr 8, 2026