Research across Rheumatoid Arthritis
Related studies from across the Rheumatoid Arthritis family.
Risk-optimized use of Janus kinase inhibitors in Japanese patients with rheumatoid arthritis depends on comorbidities
New evidence helps doctors choose safer arthritis treatments for seniors
This narrative review examines the safety and risk profile of Janus kinase inhibitors (JAKi) for rheumatoid arthritis specifically within th…
Doctors are moving toward personalized plans for rheumatoid arthritis, focusing on a patient's specific health risks rather than just their …
Stress-induced IL-6 upregulation impairs skeletal growth and bone health in children with inflammatory diseases
Stress hormones may harm bone growth in children with inflammatory conditions
This narrative review synthesizes evidence from animal models and pediatric inflammatory disorders showing that stress-induced IL-6 upregula…
A review suggests stress-induced IL-6 upregulation impairs skeletal growth and bone health in kids with inflammatory disorders, highlighting…
Short-term prednisolone bridging enables 95% discontinuation in new rheumatoid arthritis patients after 24 months
Most patients stop steroid use after a short bridge to methotrexate treatment
This randomized controlled trial enrolled 230 patients with newly diagnosed rheumatoid arthritis naive to disease-modifying antirheumatic dr…
A trial of 230 patients with new rheumatoid arthritis found that most could stop using prednisolone after just seven weeks of short-term bri…
Biologic and targeted synthetic DMARDs show reassuring malignancy safety in inflammatory arthritides, but non-melanoma skin cancer risk rises with TNF inhibitors
Biologics for arthritis: Cancer risk appears low overall
This narrative review of biologic and targeted synthetic DMARDs in immune-mediated inflammatory arthritides finds most therapies have reassu…
Most biologic arthritis drugs don't raise overall cancer risk, but skin cancer risk may be higher with some.
Meta-analysis finds rheumatoid arthritis associated with increased thyroid cancer risk in pooled cohort data
People with rheumatoid arthritis might have a higher chance of developing thyroid cancer in some groups
This meta-analysis of cohort studies involving 1,970,165 participants found a higher risk of thyroid cancer in rheumatoid arthritis patients…
A large review of nearly two million people found that those with rheumatoid arthritis could have a higher risk of thyroid cancer. This risk…
Sleep problems affect 61% of adults with rheumatoid arthritis in WHO EMRO countries
Sleep troubles hit 60.9% of adults with rheumatoid arthritis in the Eastern Mediterranean
This systematic review and meta-analysis of 2,315 adults with rheumatoid arthritis in WHO EMRO countries found sleep-related problems are hi…
Sleep problems affect more than six out of ten adults with rheumatoid arthritis in the Eastern Mediterranean. Depression and pain are the st…
Microbiota-targeted interventions for elderly-onset rheumatoid arthritis remain an area requiring further investigation
New review looks at gut health fixes for older adults with rheumatoid arthritis
This narrative review examines microbiota-targeted interventions, including dietary modifications, nutraceuticals, and fecal microbiota tran…
A new narrative review explores how changing gut bacteria might help older adults manage rheumatoid arthritis symptoms.
CD38+ NK cells may link disrupted immune tolerance in rheumatoid arthritis and colorectal cancer
Immune cells linked to cancer and arthritis show unusual activity in early review
A narrative review synthesizes evidence on CD38+ NK cells in rheumatoid arthritis and colorectal cancer, finding increased proportions in pe…
A new look at immune cells shows they behave differently in people with rheumatoid arthritis and colorectal cancer. This early review highli…
Living systematic review finds low-certainty evidence that stopping csDMARDs before surgery may increase flare risk in inflammatory arthritis
Stopping arthritis drugs before surgery may raise flare risk
This living systematic review evaluates perioperative management of conventional synthetic DMARDs in adults with rheumatoid arthritis, psori…
Low-certainty evidence suggests stopping certain arthritis drugs before surgery might increase the chance of a disease flare, but infection …
Meta-analysis of upadacitinib for rheumatoid arthritis finds similar efficacy for 15 mg and 30 mg doses
Upadacitinib improves rheumatoid arthritis symptoms in meta-analysis
This systematic review and meta-analysis of 5,237 participants with rheumatoid arthritis found that upadacitinib 15 mg and 30 mg significant…
A new analysis finds upadacitinib helps rheumatoid arthritis symptoms, but higher dose raises infection risk.
Narrative review discusses CD40/CD40L signaling regulation in rheumatoid arthritis and other autoimmune conditions
Safer CD40/CD40L targeting needs selectivity for autoimmune diseases
This narrative review examines CD40/CD40L signaling regulation in rheumatoid arthritis, systemic lupus erythematosus, and Sjogren's syndrome…
A narrative review suggests that safer therapeutic targeting of CD40/CD40L signaling will require greater selectivity to treat rheumatoid ar…
Narrative review on PAD4-mediated citrullination and PAD4-directed therapies for multiple inflammatory conditions
A new enzyme target could treat many serious diseases at once
This narrative review synthesizes evidence on PAD4-mediated citrullination and PAD4-directed therapies for conditions including rheumatoid a…
A single enzyme called PAD4 helps cause many different diseases, and new medicines targeting it might finally help people with multiple cond…