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Home › Medications › oxycodone

oxycodone

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of oxycodone

41 trials tracked of oxycodone: 26 in phase 3 or 4 and 5 with published results. The most-cited published study has 36 citations.

41Trials tracked
26Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 16 Phase 3 10 Phase 2 11 Phase 1 2 Other / NA 2
  1. Phase 3 Study of MK-0663/Etoricoxib in Postorthopedic Knee Replacement Surgery Pain (MK-0663-098) Completed · 36 cited
  2. Phase 4 An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion. Completed · 19 cited
  3. Phase 3 A Comparison of Targinact vs. Oxycodone on Gut Function After Colorectal Surgery Completed · 19 cited
  4. Phase 4 A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery Completed · 6 cited
  5. Phase 3 Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion Completed · 4 cited
  6. Phase 4 Effects of Garlic Supplements on Opioids in Healthy Volunteers Completed
Show 35 more trials
  1. Phase 4 Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms Completed
  2. Phase 4 TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy Completed
  3. Phase 4 Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects Completed
  4. Phase 4 Toward Zero Prescribed Opioids for Outpatient General Surgery Completed
  5. Phase 4 Are Opioids Needed After ACL Reconstruction Completed
  6. Phase 4 Acetaminophen (APAP) +/- Oxycodone Completed
  7. Phase 4 Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty Completed
  8. Phase 4 Pre vs Post Block in Total Knee Arthroplasty (TKA) Completed
  9. Phase 4 Study of Ketorolac Versus Opioid for Pain After Endoscopy Completed
  10. Phase 4 Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures Completed
  11. Phase 4 OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty Completed
  12. Phase 4 Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans Completed
  13. Phase 4 RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder. Completed
  14. Phase 3 Immediate-Release Oxycodone Capsules Study in Cancer Pain Completed
  15. Phase 3 Determine the Safety and Efficacy of Oxy/Nal Tablets Compared to Oxy PR in Subjects With Cancer Pain Completed
  16. Phase 3 Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA Completed
  17. Phase 3 Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy Completed
  18. Phase 3 A Study of the Effectiveness and Safety of Sustained-release Hydromorphone (a Strong Opioid) in Patients With Chronic Noncancer Pain. Completed
  19. Phase 3 Tapentadol (CG5503) Completed
  20. Phase 3 A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy. Completed
  21. Phase 2 Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients Completed
  22. Phase 2 Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain Completed
  23. Phase 2 Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain Completed
  24. Phase 2 Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy Completed
  25. Phase 2 Non-intrusive Detection of Temporary Neurologic Impairment By Opioids Completed
  26. Phase 2 Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain Completed
  27. Phase 2 Celecoxib After Tonsillectomy Completed
  28. Phase 2 Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film Completed
  29. Phase 2 Study in Subjects Undergoing Complete Abdominoplasty Completed
  30. Phase 2 Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet) Completed
  31. Phase 2 Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription Completed
  32. Phase 1 A Study on Oral and Intranasal Forms of Oxycodone in Healthy Volunteers Using Pharmacokinetic Modeling Completed
  33. Phase 1 OxyNorm® Capsules (Immediate-Release) Pharmacokinetic (PK) Study Completed
  34. N/A Emergency Department (ED) Drug Interaction in Emergency Department Patients Completed
  35. N/A Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis Completed

Showing the 41 most-cited and recently-updated of 41 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Oxycodone PCIA reduces visceral pain vs. sufentanil after repeat cesarean section
Rheumatology RCT
Oxycodone PCIA reduces visceral pain vs. sufentanil after repeat cesarean section Better Pain Relief Found for Women After Repeat C-Section
This randomized controlled trial in 100 women undergoing elective repeat cesarean section compared patient-controlled intravenous analgesia …
A new study shows a specific painkiller might work better for women having repeat C-sections.
Frontiers Apr 23, 2026
Case report of semi-implantable IDDS for advanced cancer pain in three patients
Oncology Sys. Review
Case report of semi-implantable IDDS for advanced cancer pain in three patients Can a small pump stop severe cancer pain in just one day?
This case-based study describes three representative patients with advanced cancer pain treated with a semi-implantable intrathecal drug del…
A small pump delivered direct spinal medicine to three advanced cancer patients, dropping their worst pain from near maximum to zero within …
Frontiers Apr 16, 2026