3HP with SMS reminders increases treatment completion to 84.9% compared to 65.4% for 4RIF
SMS reminders help more people finish tuberculosis treatment
This randomized controlled trial of 210 individuals with tuberculosis infection found that 3HP with SMS reminders resulted in a higher treat…
A new trial shows that a shorter treatment plan paired with text message reminders helps more people finish their tuberculosis medication.
Short course regimens 3HP, 4HR, and 4R show higher adherence and lower active cases than 9H
Short Treatment Courses May Reduce Tuberculosis Cases in Children
This network meta-analysis evaluates treatment regimens for children and adolescents with TB infection. The study finds that 4HR reduces act…
New analysis suggests shorter drug regimens for children with tuberculosis may improve treatment completion and reduce the number of active …
Dasatinib therapy in pediatric ALL may cause chylothorax and Bartonella henselae infection
Dasatinib May Cause Chylothorax and Cat-Scratch Disease in Leukemia
This case report and systematic review describes a 14-year-old boy with Ph+ acute lymphoblastic leukemia treated with dasatinib who develope…
A 14-year-old on dasatinib for leukemia developed chylothorax and cat-scratch disease, a rare double complication.
Sensititre MYCOTB shows high diagnostic accuracy for rifampicin and isoniazid in tuberculosis isolates
New test shows high accuracy for detecting drug resistant tuberculosis
This meta-analysis of 1,728 isolates evaluates the diagnostic performance of Sensititre MYCOTB against reference drug susceptibility testing…
A new testing method shows high accuracy in identifying which drugs can successfully treat drug-resistant tuberculosis infections.
WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection
New tools help doctors identify drug resistant tuberculosis strains
This meta-analysis of 144,623 M. tuberculosis genomes evaluates six open-access WGS-based drug susceptibility testing prediction tools. The …
New computer tools can accurately predict if common drugs will work against tuberculosis, helping doctors choose the right treatment faster.
Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen
Trial Shows Rifapentine Dosage Impacts Tuberculosis Treatment Outcomes
This Phase 2/3 Stage 1 randomized controlled trial of 400 adults with pulmonary drug-susceptible tuberculosis compared three 4-month rifapen…
A new clinical trial explores how different doses of rifapentine affect treatment success and safety for patients with drug-susceptible tube…
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
Identifying key risks for drug resistant tuberculosis infections in Cameroon
This meta-analysis of 28 studies involving 9,931 patients identifies a 5.2% pooled prevalence of multidrug-resistant tuberculosis (MDR-TB) i…
New data shows that past infections and lifestyle factors like alcohol use can increase the risk of developing hard-to-treat tuberculosis.
High-dose rifampicin pharmacokinetics differ across sites in tuberculosis infection randomized trial
High-dose rifampicin shows different drug levels in adults across three countries
This randomized controlled trial evaluated adults and adolescents aged ≥ 10 years with tuberculosis infection.
Drug levels of high-dose rifampicin varied by country, with lower bioavailability seen in Canada and Vietnam compared to Indonesia in this t…