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Infectious Disease
Meta-analysis
Sensititre MYCOTB shows high diagnostic accuracy for rifampicin and isoniazid in tuberculosis isolates
New test shows high accuracy for detecting drug resistant tuberculosis
This meta-analysis of 1,728 isolates evaluates the diagnostic performance of Sensititre MYCOTB against reference drug susceptibility testing…
A new testing method shows high accuracy in identifying which drugs can successfully treat drug-resistant tuberculosis infections.
Sep 11, 2026
Infectious Disease
Meta-analysis
WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection
New tools help doctors identify drug resistant tuberculosis strains
This meta-analysis of 144,623 M. tuberculosis genomes evaluates six open-access WGS-based drug susceptibility testing prediction tools. The …
New computer tools can accurately predict if common drugs will work against tuberculosis, helping doctors choose the right treatment faster.
Aug 12, 2026
Infectious Disease
RCT
Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen
Trial Shows Rifapentine Dosage Impacts Tuberculosis Treatment Outcomes
This Phase 2/3 Stage 1 randomized controlled trial of 400 adults with pulmonary drug-susceptible tuberculosis compared three 4-month rifapen…
A new clinical trial explores how different doses of rifapentine affect treatment success and safety for patients with drug-susceptible tube…
Aug 3, 2026
Infectious Disease
Meta-analysis
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
Identifying key risks for drug resistant tuberculosis infections in Cameroon
This meta-analysis of 28 studies involving 9,931 patients identifies a 5.2% pooled prevalence of multidrug-resistant tuberculosis (MDR-TB) i…
New data shows that past infections and lifestyle factors like alcohol use can increase the risk of developing hard-to-treat tuberculosis.
medRxiv
Jul 18, 2026
Pediatrics
RCT
High-dose rifampicin pharmacokinetics differ across sites in tuberculosis infection randomized trial
High-dose rifampicin shows different drug levels in adults across three countries
This randomized controlled trial evaluated adults and adolescents aged ≥ 10 years with tuberculosis infection.
Drug levels of high-dose rifampicin varied by country, with lower bioavailability seen in Canada and Vietnam compared to Indonesia in this t…
Apr 30, 2026