N/A N=39 Nitrous Oxide Versus Intravenous Sedation for Anesthesia
Pregnancy Termination in Second Trimester
Primary: Visual Analog Scale (VAS) Score for Maximum Procedural Pain — 54.1; 34.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=199 Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
Lumbar Spondylosis · Cervical Spondylosis · Hip Osteoarthritis
Primary: Change in Neurocognitive Performance (Z-score) — .09; -.20; -.42; .01 z score
Phase 4 N=72 Total Intravenous Anesthesia in Sinus Surgery
Advanced Chronic Rhinosinusitis
Primary: Intraoperative Visual Field Assessment — 3.3; 4.3; 3.3; 4.2 units on a scale
N/A N=30 Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients
Idiopathic Scoliosis
Primary: Amplitude Required to Elicit the MEP — 307; 417 milliamperes
N/A N=67 The Effect of Intravenous Anesthetics on Fear Learning and Memory
Phobias
Primary: GSR Trial 1 — .62; .55; .55; .67 units on a scale
N/A N=28 Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection
Macular Degeneration
Primary: Discomfort Associated With the Intravitreal Injection — 3; 2.3; 2.8; 3.1 units on a scale — p=0.28
Phase 2 N=49 Anesthetics to Prevent Lung Injury in Cardiac Surgery
Inflammatory Lung Injury · Ischemia-Reperfusion Lung Injury · Postoperative Pulmonary Complications
Primary: Bronchoalveolar Lavage (BAL) Concentration of TNF Alpha (pg/mL) — 0.53; 0.53; 22.06; 102.04 pg/mL
N/A N=116 Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Spine Surgery
Primary: Mean Pain Scores — 4.4; 5.3 verbal response scores — p=<0.001
Phase 4 N=50 Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
Shoulder Pain
Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants
N/A N=100 Anaesthesia for Laparoscopic Sleeve Gastrectomy
Obese
Primary: Analgesic Requirements. — 3.56; 1.67 mg
Phase 4 N=32 Angiotensin II in General Anesthesia
Hypertension
Primary: Median Dose Required to Increase the Systolic Blood Pressure (SBP) — 35; 43; 45 ng/kg/min
N/A N=139 Automatic Control of Total Intravenous Anesthesia (ACTIVA)
Anesthesia
Primary: Depth of Hypnosis Adequacy — 79.4; 16.2 percentage of maintenance duration
N/A N=51 Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Hypotension · Anesthesia
Primary: Number of Participants Who Had Hypotensive Events — 8; 21 Participants — p=0.01
N/A N=102 ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
Acute Pain
Primary: The Incidence of Severe Postoperative Pain — 49; 53 Participants
N/A N=57 Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival
Age-related Macular Degeneration · Central Retinal Vein Occlusion · Diabetic Macular Edema
Primary: Number of Participants Who Preferred Subconjunctival Anesthetic at the Third Follow-up Visit — 50 participants
N/A N=309 A Comparison of Inhalation vs. Intravenous Induction
Hypothermia
Primary: Measurement of Core Temperature — 36.42; 36.44; 35.96; 36.35 degree C
N/A N=1,122 Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice
Anesthesia, General
Primary: Time to Loss of Consciousness of Patients Administered Anesthesia — 2.7 Minutes
Phase 3 N=94 Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
Sedation
Primary: Percentage of Time of Adequately Maintained Sedation Depth up to 48 Hours (± 6 Hours) — 62.37; 68.94 Percentage of time
N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
N/A N=33 Intraoperative Bleeding During Endoscopic Sinus Surgery
Blood Loss
Primary: Estimated Blood Loss — 78.5; 80.3 mL/h — p=0.937
Phase 4 N=23 Anesthesia and Postoperative Pain
Postoperative Pain
Primary: Score on a Pain Rating Scale (Numerical Analog Score) — 1.5; 4.9 scores on a scale
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
Phase 3 N=509 Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery
Coronary Artery Disease · General Anesthetic Drug Allergy · Coronary Artery Bypass Graft Surgery
Primary: Blood Level of Troponin I — 2.16; 2.57 ng/mL — p=0.02
Phase 3 N=159 IVPCA in the Management of Pain Following Major Intracranial Surgery
Intracranial Surgery
Primary: Hourly Pain Scores — 2.5; 3.6; 3.7; 5.2 units on a scale
Phase 2 N=12 EEG Studies of Sevoflurane-Induced General Anesthesia
Anesthesia
Primary: Frequencies At Which Changes in Alpha, Theta, and Slow-Delta Wave Power Were Observed From Baseline During Sevoflurane-induced General Anesthesia — 10; 5; 1 Hz
Phase 4 N=150 Local Anesthetics for Pain Reduction Prior to IV Line Placement
Pain · Local Anesthesia for Peripheral Intravenous Catheterization
Primary: Pain Score Following Anesthetic Administration — 2.81; 1.64; 2.05 units on a scale
N/A N=105 Anesthesia and Lymphocytes Apoptosis
Anesthesia
Primary: Lymphocyte Count — 0.55; 0.73; 0.73 cells/nanoliter
N/A N=67 Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol
Liver Dysfunction
Primary: Changes in the M30 and M65 Markers Related to the Anesthesia Type — 237.27; 279.97; 427.33; 470.30 U/L
N/A N=63 Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia
Cardiovascular Abnormalities
Primary: Change in Plasma Total Homocysteine Concentration (tHcy) — 1.9; 2.7; 0.5 mcmol/L — p=<0.05
Phase 4 N=98 An Evaluation of the Effectiveness of Local Anesthetics Used During Intravenous Catheter Insertion
IV Insertion Pain
Primary: Differences in Patients' Perceptions of Pain Between Treatment Methods — 0.015; 0; 0; 1.909 units on a scale