N/A N=57 Insulin-sensitive Obesity: Lessons From Longitudinal Data
Insulin Sensitivity/Resistance · Obesity
Primary: Insulin Sensitivity — 0.0105; -0.0076; 0.0041 micro mol/min/Kg/mU/L/year
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=47 Healthy Bodies, Healthy Kids
Child Mental Disorders · Obesity · Metabolic Syndrome
Primary: DEXA-measured Adiposity — 0.76; -0.43; -2.79 kilograms — p=0.01
N/A N=80 Effects of Obesity Treatments on Food Preferences and Metabolism
Obesity · Type 2 Diabetes Mellitus
Primary: Change in Energy Intake From Baseline — 500; 310; 482; 5 kcal
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
N/A N=314 Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Obesity · PreDiabetes · Aging
Primary: Change in Bodyweight — -7.4; -6.1 percentage of bodyweight change — p=0.196
N/A N=51 Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
Obesity
Primary: Total Myocardial Oxygen Consumption (MVO2) — 1064; 1202; 947; 835 µmol/min
N/A N=50 Bariatric Surgery for Morbid Obesity
Obesity · Morbid Obesity
Primary: Size of Adipocytes — 73.4; 99.0; 103.0 µm
N/A N=12 Metabolic Syndrome and Fall Risk
Metabolic Syndrome · Autonomic Neuropathy
Primary: Four Square Step Test (FSST) — 11.04; 14.29 seconds
N/A N=81 Effects of Different Surgical Methods to Treat Obesity
Obesity · Type 2 Diabetes · Insulin Sensitivity
Primary: Insulin Sensitivity at 2 Years — 6.7; 6.6 glucose/kg body weight/min
N/A N=28 Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity
Overweight and Obesity · Insulin Resistance
Primary: Percent Change in Serum Myostatin Levels From Pre- to 3 Hours Post-exercise — -6.9; 8.5 % change in serum myostatin — p=0.303
N/A N=53 Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
Obesity
Primary: Change in Fat Mass at 12 Weeks — -0.74; 0.42 kg
N/A N=32 The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes
Type 1 Diabetes
Primary: Energy Expenditure — 1978.3; 1969.8; 2414.8; 1497.7 Kilocalories — p=0.24
N/A N=38 Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)
Obesity · Weight Loss · CHD - Coronary Heart Disease
Primary: Feasibility - Number of Enrolled Participants — 38 Participants
N/A N=40 Effects of Obesity and Physical Inactivity on Pregnancy Outcomes
Obesity · Sedentary
Primary: Neonatal Adiposity — 11.2; 12.4 % fat
Phase 2 N=34 Biological Effects of Weight Loss In Older, Obese Women
Obesity · Sarcopenia
Primary: Performance on the 400 Meter Walk — 0.16; 0.02 meters per second — p=<0.05
N/A N=61 Healthy Weight for Teens
Obesity
Primary: Number of Participants With Successful Implemenmtation of BPE (Bundle of Program Enhancements) in Existing Multi-component PWM Programs — 20; 12 Participants
N/A N=30 Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome Pathologies
Metabolic Syndrome · Diabetes Mellitus, Type 2 · Pre Diabetes
Primary: Hemoglobin A1c — -.42; -0.37; 0.02 % of hemoglobin — p=0.001
N/A N=38 Mechanisms of Obesity and Its Metabolic Complications in Youth
Obesity, Childhood
Primary: Rate of Appearance of Acetate — 7.40; 7.69; 9.29; 14.7 umol/kg/min
Phase 4 N=70 Mechanisms Underlying Metabolic Syndrome in Obesity
Metabolic Syndrome · Insulin Resistance · Prediabetes
Primary: Change in Insulin Sensitivity Using FSIGT — 1.7; 2.4; 7.02 FSIGT units (x10^-4/min/uU/ml)
N/A N=213 Maintenance-Tailored Obesity Treatment
Obesity
Primary: Change in Body Weight — 9.3; 8.3 kg
N/A N=16 The Role of Altered Nutrient Partitioning in Food Reward
Overweight and Obesity
Primary: Change in Preference- Liking — 6.5; 4.5 units on a scale
N/A N=222 Maintenance After Initiation of Nutrition TrAINing
Obesity
Primary: Weight — 99.2; 105.7 kilograms — p=.04
Phase 2 N=125 PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction
Healthy · Obese
Primary: Resting Energy Expenditure After 12 Weeks of Drug Therapy (kcal/Day) — 1267; 1268 kcal/day
N/A N=28 Increased Monitoring of Physical Activity and Calories With Technology
Weight Change, Body · Behavior, Health · Obesity, Childhood
Primary: BMI Percentile — 98.46; 99.37 BMI percentile for age and sex
N/A N=33 Time Restricted Eating for Metabolic and Psychological Optimization
Mild Cognitive Impairment · Obesity
Primary: Change in Memory Composite Rank — 6.22 rank — p=<0.001
N/A N=20 Protection Against Insulin Resistance in Obesity
Obesity · Insulin Resistance
Primary: Insulin Sensitivity — 273; 817 nmol/kg FFM/min /(µU/mL Insulin)
N/A N=22 Regulation of Muscle Protein Phenotype in Humans With Obesity
Obesity
Primary: Whole-Muscle Protein Synthesis — 0.004; 0.015 %/hr
N/A N=79 Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
Weight Loss · Anovulation · Amenorrhea
Primary: Change From Baseline Ovulatory/Menstrual Function — 12; 18 Participants
N/A N=17 TRE With Physical Activity for Weight Management
Pre Diabetes · Overweight and Obesity
Primary: Body Weight Changes Between Week 1 to Week 10 — -2.1; -4.2; -1.3; .1 Percent body weight loss
N/A N=30 Obesity - Inflammation - Metabolic Disease: Effect of Lactobacillus Casei Shirota
Metabolic Syndrome
Primary: Change of Neutrophil Phagocytosis From Baseline to 3 Months — 0.06; 3.48 percentage of monocytes and granulocytes