N/A N=67 The Effect of Intravenous Anesthetics on Fear Learning and Memory
Phobias
Primary: GSR Trial 1 — .62; .55; .55; .67 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=309 A Comparison of Inhalation vs. Intravenous Induction
Hypothermia
Primary: Measurement of Core Temperature — 36.42; 36.44; 35.96; 36.35 degree C
N/A N=51 Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Hypotension · Anesthesia
Primary: Number of Participants Who Had Hypotensive Events — 8; 21 Participants — p=0.01
Phase 4 N=32 Angiotensin II in General Anesthesia
Hypertension
Primary: Median Dose Required to Increase the Systolic Blood Pressure (SBP) — 35; 43; 45 ng/kg/min
Phase 2 N=49 Anesthetics to Prevent Lung Injury in Cardiac Surgery
Inflammatory Lung Injury · Ischemia-Reperfusion Lung Injury · Postoperative Pulmonary Complications
Primary: Bronchoalveolar Lavage (BAL) Concentration of TNF Alpha (pg/mL) — 0.53; 0.53; 22.06; 102.04 pg/mL
N/A N=199 Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
Lumbar Spondylosis · Cervical Spondylosis · Hip Osteoarthritis
Primary: Change in Neurocognitive Performance (Z-score) — .09; -.20; -.42; .01 z score
N/A N=105 Anesthesia and Lymphocytes Apoptosis
Anesthesia
Primary: Lymphocyte Count — 0.55; 0.73; 0.73 cells/nanoliter
Phase 2 N=12 EEG Studies of Sevoflurane-Induced General Anesthesia
Anesthesia
Primary: Frequencies At Which Changes in Alpha, Theta, and Slow-Delta Wave Power Were Observed From Baseline During Sevoflurane-induced General Anesthesia — 10; 5; 1 Hz
Phase 4 N=2,367 Randomized Trial of Sedative Choice for Intubation
Acute Respiratory Failure
Primary: All-cause, 28-day, In-hospital Mortality — 330; 345 Participants
Phase 4 N=50 Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
Shoulder Pain
Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants
N/A N=1,122 Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice
Anesthesia, General
Primary: Time to Loss of Consciousness of Patients Administered Anesthesia — 2.7 Minutes
N/A N=68 Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Postoperative Pain
Primary: EC50 for Successful Intubation in Each Groups — 3.00; 2.00; 1.29 vol%
N/A N=54 Ketamine Infusion and Hypoventilation
Hypoventilation
Primary: Intraoperative Hypoventilation — 1.2; 65 % time
Phase 3 N=509 Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery
Coronary Artery Disease · General Anesthetic Drug Allergy · Coronary Artery Bypass Graft Surgery
Primary: Blood Level of Troponin I — 2.16; 2.57 ng/mL — p=0.02
N/A N=67 Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol
Liver Dysfunction
Primary: Changes in the M30 and M65 Markers Related to the Anesthesia Type — 237.27; 279.97; 427.33; 470.30 U/L
N/A N=39 Nitrous Oxide Versus Intravenous Sedation for Anesthesia
Pregnancy Termination in Second Trimester
Primary: Visual Analog Scale (VAS) Score for Maximum Procedural Pain — 54.1; 34.0 units on a scale
Phase 4 N=160 Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures
Blood Loss · Anesthesia
Primary: Number of Participants Needing Intervention to Treat Blood Loss (a Composite of Use of Uterotonics, Re-aspiration, and Bimanual Massage) — 20; 13 Participants
N/A N=28 Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection
Macular Degeneration
Primary: Discomfort Associated With the Intravitreal Injection — 3; 2.3; 2.8; 3.1 units on a scale — p=0.28
Phase 4 N=72 Total Intravenous Anesthesia in Sinus Surgery
Advanced Chronic Rhinosinusitis
Primary: Intraoperative Visual Field Assessment — 3.3; 4.3; 3.3; 4.2 units on a scale
N/A N=121 Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence Delirium
Primary: Emergence Agitation — 3.9; 2.5 Score on a scale — p=0.001
Phase 3 N=94 Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
Sedation
Primary: Percentage of Time of Adequately Maintained Sedation Depth up to 48 Hours (± 6 Hours) — 62.37; 68.94 Percentage of time
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
Phase 4 N=56 Ketamine and Propofol for Upper Endoscopy
Anesthesia
Primary: Dose of Propofol Required to Prevent Movement (Response) to Insertion of Endoscope Into the Patient's Esophagus — 6.1; 4.5; 4.7; 1.1 mg/kg
N/A N=142 A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain
Adult Intracranial Tumor · Adult Solid Tumor
Primary: Hemodynamics — 98; 88 mmHg — p=< 0.001
Phase 4 N=41 Cognitive Functions After TIVA With Dexmedetomidine
Postoperative Confusion
Primary: Mini Mental State Examination (MMSE) Score at the Second Hour After Surgery — 27.40; 26.45 scores on a scale
N/A N=31 Characterizing the Electroencephalogram Signature of Fentanyl During Induction of General Anesthesia
Anesthesia
Primary: Slope of EEG Theta Band Power Over Fentanyl Effect Site Concentration (dB/ng/mL) — 0.55 dB / nano gram / mL
N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
N/A N=1,365 Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Requiring General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on the Cardiovascular System in Common Clinical Practice
Anesthesia, General
Primary: Time to Loss of Consciousness of Patients Administered Anesthesia — 3.0 minutes
Phase 4 N=99 Propofol in Emergence Agitation
Emergence Agitation
Primary: Number of Participants With Emergent Agitation — 16; 24 Participants
Phase 4 N=124 Effect of Intraoperative Anesthetic Management on Postoperative Nausea and Vomiting in Bariatric Surgery
Postoperative Nausea and Vomiting
Primary: PONV During the First 24 Hours After Bariatric Surgery — 22; 12 participants — p=0.04