N/A N=198 Discharge Medication Counseling in Hospitalized Children
Medication Management
Primary: Observed Dosing Accuracy — 3.3; 1.0 percent difference — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=149 Medication Education for Dosing Safety
Pain · Fever
Primary: Number of Participants Reporting Safe Dosing at 48-72 Hours — 28; 25 Participants
N/A N=306 Pharmacists and Pharmacy Technicians to Improve Admission Medication History Accuracy
Adverse Drug Events
Primary: Mean Severity-weighted Admission Medication History (AMH) Error Score — 23; 4.1; 4.1 Mean Severity-weighted AMH Error Score
N/A N=150 Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
Cardiopulmonary Arrest · Resuscitation · Pediatrics
Primary: Medication Dosage Errors — 5.7; 62.8 percentage of medication errors
N/A N=396 Achieving Medication Safety During Acute Kidney Injury
Kidney Failure, Acute
Primary: Adverse Drug Events or Potential Adverse Drug Events — 99; 104 Patient-Medication Pairs
N/A N=156 Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care
Adverse Drug Events
Primary: Health Services Utilization 3 Months Following Hospital Discharge — 3.33; 3.40 Health Services Utilizations — p=.87
N/A N=862 Pharmacist Intervention to Decrease Medication Errors in Heart Disease Patients (The PILL-CVD Study)
Acute Coronary Syndrome · Heart Failure
Primary: Number of Serious Medication Errors as Determined by Interview and Medical Chart Review — 0.95; 0.87 serious medication errors
N/A N=494 PictureRx: Improving Medication Safety in Health Disparity Populations
Medication Reconciliation
Primary: Number of Participants With Changes/Updates in Medication List — 101; 43 Participants — p=<0.0001
N/A N=66 Mobile Application to Enhance Medication Management
Medication Adherence · Mobile Application
Primary: Usability of the SAM App — 1.14; 1.32; 1.35; 1.81 score on a scale
N/A N=68 Preventing Medication Dispensing Errors in Pharmacy Practice With Interpretable Machine Intelligence
Machine Intelligence in the Pharmacy
Primary: Reaction Time — 3668; 4727; 4510 millisecond (ms)
N/A N=402 Regional Data Exchange to Improve Medication Safety
Drug Toxicity
Primary: Transition Drug Risk — 6.4; 5.8 units: risk-weighted discrepancies — p=0.175
N/A N=3,356 Risk of Wrong-Patient Errors With Multiple Records Open
Medical Errors · Medical Order Entry Systems
Primary: Wrong-patient Order Sessions, Defined as Order Sessions That Include at Least One Wrong-Patient Retract-and-Reorder (RAR) Event, As-randomized Analysis — 3015; 3058…
N/A N=19 The Adverse Drug Reaction (ADRe) Profile for Polypharmacy
Polypharmacy
Primary: Number of Participants With Changes in Signs and Symptoms Related to Adverse Effects of Prescribed Medicines. Clinical Gains and Benefits to Residents — 17 Participants
N/A N=52 The Medication Metronome Project - Study to Facilitate Follow-up Testing Resulting From Prescribed Medications to Improve Patient Safety and Care
Diabetes Mellitus, Type 2 · Hypertension · Hyperlipidemia
Primary: Primary Effectiveness Outcome - LDL — 57.9; 54.8 percentage of time spent at goal
N/A N=23 Detecting Errors In Using Metered Dose Inhalers (MDI) Among Asthma And Chronic Obstructive Pulmonary Disease (COPD) Patients
Asthma · Chronic Obstructive Pulmonary Disease
Primary: Inhaler Use Correctness — 3.52 correct steps
N/A N=39 Minimizing Harm From ADEs by Improving Nurse-Physician Communication
Interdisciplinary Communication · Management, Medication Therapy
Primary: Incident Rate for Communication Events — 47.6; 34.74; 34.07 mean events per observation — p=0.01
N/A N=10,426 Evaluating the Impact of Patient Photographs for Preventing Wrong-Patient Errors
Medical Errors · Electronic Medical Records
Primary: Number of Order Sessions With at Least One Retract-and-Reorder (RAR) Event as Identified by the Wrong-Patient Retract-and-Reorder (RAR) Measure. — 5587; 5836; 5598; 6279…
N/A N=14,442 A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease
Alzheimer Disease
Primary: Time to Dispensing of Inappropriate Medication Prescription — 76.7; 77.9; 77.5 Percentage of Cumulative Incidence — p=0.76
N/A N=1,005 Testing a Medication Risk Communication and Surveillance Strategy: The EMC2 Trial
High-risk Medications
Primary: Medication Knowledge (0-100) — 71.2; 71.9; 73.2; 74.9 score on a scale
N/A N=2,196 Improving Transplant Medication Safety Through A Technology and Pharmacist Intervention
Transplant
Primary: Any Hospitalization or Any Emergency Room Visits — 497; 574; 380; 391 Participants — p=<.001
N/A N=440 Family Activation and Communication About Errors and Safety (FACES)
Family Reported Errors and Adverse Events
Primary: Family Safety Reporting Rates — 61; 60 Participants
N/A N=40 Assessing the Effectiveness and Safety of the ID-Cap System for Medication Monitoring and Adherence
Medication Adherence
Primary: Medication Adherence — 94.8; 82.8 percentage of doses taken
N/A N=99 Loading Vancomycin Doses in the Emergency Department
Infectious Disease
Primary: Percentage of Participants First Achieving Therapeutic Levels at 36 Hours — 20; 18 percentage of participants
N/A N=1,146 NUDGE-EHR Replication Trial at Mass General Brigham
Aging · Benzodiazepine Sedative Adverse Reaction · Anticholinergic Adverse Reaction
Primary: Change in Inappropriate Prescribing — 106; 145; 122 Participants — p=0.002
N/A N=301 Development and Evaluation of an Electronic Health Record-based Medication Complete Communication (EMC2) Strategy
Medication Adherence
Primary: Medication Specific Knowledge — 63.82; 62.80 score (0-100)
N/A N=24 RxConnect User Testing Study
Behavior
Primary: Number of Prescribing Errors by Study Arm — 8; 34; 8; 31 Medication orders
N/A N=60 Smart Capsule for Automatic Adherence Monitoring
Medication Adherence
Primary: Medication Adherence — 88.1; 96.6; 94.4 percentage of doses taken (pill count)
Phase 4 N=111 Study to Evaluate Handling Errors in Usage of SERETIDE® Metered Dose Inhaler (MDI) (EVOHALER®) by Adult Subjects Currently Using the SERETIDE DISKUS® Inhaler
Asthma
Primary: Percentage of Participants Making at Least One Critical Error After the First Assessment of Metered Dose Inhaler (MDI) Technique on Day 14 — 14 Percentage of Participants
Phase 2 N=99 Volumes of Administration for Intranasal Midazolam
Children Requiring Sedation to Facilitate Laceration Repair
Primary: Median Time (Minutes) After Administration of Intranasal Midazolam Until Patient Achieves Minimal Sedation — 4.7; 4.3; 5.2 minutes
N/A N=63 Takepron Intravenous 30 mg Specified Drug-use Survey [Acute Stress Ulcer and Acute Gastric Mucosal Lesions]
Acute Stress Ulcer and Acute Gastric Mucosal Lesions
Primary: Number of Participants Reporting One or More Adverse Drug Reactions — 0 participants